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公开(公告)号:US20070203064A1
公开(公告)日:2007-08-30
申请号:US11554253
申请日:2006-10-30
申请人: Karen Duffy , Mark Cunningham , M. Mbow , Robert Sarisky
发明人: Karen Duffy , Mark Cunningham , M. Mbow , Robert Sarisky
IPC分类号: A61K38/17 , A61K48/00 , C07K14/705
CPC分类号: C07K14/705 , A61K38/00 , A61K48/00
摘要: TLR3 glycosylation site muteins, nucleic acids encoding the muteins, and methods of modulating TLR3 activity in a cell are disclosed.
摘要翻译: 公开了TLR3糖基化位点突变蛋白,编码突变蛋白的核酸和调节细胞中TLR3活性的方法。
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公开(公告)号:US20050244410A1
公开(公告)日:2005-11-03
申请号:US10835475
申请日:2004-04-29
申请人: Ashlyn Bassiri , Anuk Das , Susan Dillon , Karen Duffy , Jonathan Seideman , M. Mbow , Lars Karlsson , Siquan Sun , Jian Zhu , Mark Cunningham
发明人: Ashlyn Bassiri , Anuk Das , Susan Dillon , Karen Duffy , Jonathan Seideman , M. Mbow , Lars Karlsson , Siquan Sun , Jian Zhu , Mark Cunningham
IPC分类号: A61K39/395 , A61K48/00 , C07K16/28
CPC分类号: C07K16/2896 , C07K2317/34
摘要: Cell surface TLR9 and TLR9 ligand binding agents are disclosed. The binding agents include antibodies and other proteins. The binding agents are useful as therapeutics, diagnostics or research reagents.
摘要翻译: 公开了细胞表面TLR9和TLR9配体结合剂。 结合剂包括抗体和其它蛋白质。 结合剂可用作治疗剂,诊断或研究试剂。
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公开(公告)号:US20060194956A1
公开(公告)日:2006-08-31
申请号:US11414106
申请日:2006-04-28
申请人: Jill Giles-Komar , Roberta Lamb , M. Mbow
发明人: Jill Giles-Komar , Roberta Lamb , M. Mbow
摘要: Methods for generating antibodies in rodents are disclosed. The antibodies are useful as therapeutic agents, diagnostic agents or research reagents.
摘要翻译: 公开了在啮齿动物中产生抗体的方法。 抗体可用作治疗剂,诊断剂或研究试剂。
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