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18 条记录 (耗时 0.019 秒)

    Anti-Inflammatory Analgesic External Preparation
    1.
    发明申请
    Anti-Inflammatory Analgesic External Preparation 审中-公开
    抗炎镇痛外用药

    公开(公告)号：US20110160194A1

    公开(公告)日：2011-06-30

    申请号：US12999164

    申请日：2009-06-12

    申请人： Katsuyuki Inoo ,  Mitsuhiro Kawada

    发明人： Katsuyuki Inoo ,  Mitsuhiro Kawada

    IPC分类号： A61K31/5415 ,  A61K31/405 ,  A61K31/192 ,  A61K31/196 ,  A61K31/24 ,  A61K31/381 ,  A61P25/00

    CPC分类号： A61K9/7038 ,  A61K9/7023 ,  A61K31/165 ,  A61K31/192 ,  A61K31/245 ,  A61K31/381 ,  A61K31/405 ,  A61K31/5415 ,  A61K45/06 ,  A61K2300/00

    摘要： An external preparation that effectively produces the anti-inflammatory analgesic effect of a non-steroidal anti-inflammatory analgesic agent, and reduces skin irritation on the application site of the preparation and has an excellent effect on pain associated with inflammation such as chronic rheumatoid arthritis, osteoarthritis, and also lumbago is provided. The external preparation includes a non-steroidal anti-inflammatory analgesic agent and oxybuprocaine or a pharmaceutically acceptable salt thereof. The external preparation includes the non-steroidal anti-inflammatory analgesic agent at a content of 0.1 to 10 wt % based on the total weight of the formulation and oxybuprocaine or a pharmaceutically acceptable salt thereof at a content of 0.01 to 60 wt % based on the total weight of the formulation. The external preparation has a dosage form as an external preparation wherein the dosage form is an ointment, a solution, a suspension, an emulsion, a lotion, a cataplasm, a tape, an aerosol, or a powder for external use.

    摘要翻译： 一种外用制剂，其有效地产生非甾体抗炎止痛剂的消炎镇痛作用，并减少制剂施用部位的皮肤刺激，并且对与炎症有关的疼痛具有优异的作用，例如慢性类风湿性关节炎， 骨关节炎，还有腰痛。 外用制剂包括非类固醇消炎止痛剂和羟普鲁卡因或其药学上可接受的盐。 外用制剂包括非甾体抗炎止痛剂，其含量为0.1至10重量％，基于制剂的总重量和基于以下物质的0.01-60重量％的奥布对卡因或其药学上可接受的盐 制剂的总重量。 外用制剂具有作为外用制剂的剂型，其中剂型为软膏剂，溶液剂，悬浮液剂，乳剂剂，洗剂剂，粘膜剂，胶带剂，气雾剂或外用粉剂。

    Oxybuprocaine-Containing Analgesic/Antipruritic External Preparation
    2.
    发明申请
    Oxybuprocaine-Containing Analgesic/Antipruritic External Preparation 审中-公开
    含有奥泊普卡因的镇痛/止痒剂外用制剂

    公开(公告)号：US20110124727A1

    公开(公告)日：2011-05-26

    申请号：US12999195

    申请日：2009-06-12

    申请人： Katsuyuki Inoo ,  Mitsuhiro Kawada ,  Kenjiro Mori

    发明人： Katsuyuki Inoo ,  Mitsuhiro Kawada ,  Kenjiro Mori

    IPC分类号： A61K31/245 ,  C07C229/64 ,  A61P29/00 ,  A61P17/00 ,  A61P17/04

    CPC分类号： A61K9/7053 ,  A61K9/7076 ,  A61K31/13 ,  A61K31/245

    摘要： An analgesic/antipruritic external preparation that includes a local anesthetic, has fewer side effects, and has an excellent therapeutic effect on pain and itching of the skin is provided. The analgesic/antipruritic external preparation includes oxybuprocaine or a pharmaceutically acceptable salt thereof as an active ingredient, and the oxybuprocaine or a pharmaceutically acceptable salt thereof is contained in an amount of 0.1 to 60 wt %, more preferably 1 to 40 wt %, and most preferably 5 to 30 wt %. The analgesic/antipruritic external preparation has a dosage form as an external preparation wherein the dosage form is an ointment, a solution, a suspension, an emulsion, a lotion, a cataplasm, a tape, an aerosol, or a powder for external use.

    摘要翻译： 提供了包含局部麻醉剂的镇痛/止痒剂外用剂，副作用较少，对疼痛和皮肤瘙痒具有优异的治疗作用。 止痛/止痒剂外用制剂包括活性成分的布比卡因或其药学上可接受的盐，并且含有布比卡因或其药学上可接受的盐的含量为0.1〜60重量％，更优选为1〜40重量％ 优选为5〜30重量％。 止痛/止痒外用制剂具有作为外用制剂的剂型，其中剂型为软膏剂，溶液剂，悬浮液剂，乳剂剂，洗剂剂，粘膜剂，胶带剂，气雾剂或外用粉剂。

    Methods of transdermally administering an indole serotonin receptor agonist and transdermal compositions for use in the same
    4.
    发明授权
    Methods of transdermally administering an indole serotonin receptor agonist and transdermal compositions for use in the same 失效
    透皮给药吲哚类5-羟色胺受体激动剂的方法和用于其中的透皮组合物

    公开(公告)号：US08609134B2

    公开(公告)日：2013-12-17

    申请号：US12877848

    申请日：2010-09-08

    申请人： Kunio Yoneto ,  Katsuyuki Inoo

    发明人： Kunio Yoneto ,  Katsuyuki Inoo

    IPC分类号： A61K9/70 ,  A61F13/00

    CPC分类号： A61K31/405 ,  A61K9/7053 ,  A61K9/7061

    摘要： Methods of transdermally delivering a therapeutic amount of an indole serotonin receptor agonist to an individual in need thereof, e.g., to provide a therapeutic level of an indole serotonin receptor agonist to an individual in need thereof, are provided. Also provided are transdermal formulations of indole serotonin receptor agonists that find use in practicing the subject methods.

    摘要翻译： 提供了将治疗量的吲哚5-羟色胺受体激动剂透皮递送给有需要的个体的方法，例如向有需要的个体提供治疗水平的吲哚5-羟色胺受体激动剂。 还提供了可用于实践本发明方法的吲哚5-羟色胺受体激动剂的透皮制剂。

    METHODS OF TRANSDERMALLY ADMINISTERING AN INDOLE SEROTONIN RECEPTOR AGONIST AND TRANSDERMAL COMPOSITIONS FOR USE IN THE SAME
    6.
    发明申请
    METHODS OF TRANSDERMALLY ADMINISTERING AN INDOLE SEROTONIN RECEPTOR AGONIST AND TRANSDERMAL COMPOSITIONS FOR USE IN THE SAME 失效
    一种用于使用内含子糖蛋白受体激动剂和变态组合物进行转导的方法

    公开(公告)号：US20070140977A1

    公开(公告)日：2007-06-21

    申请号：US11561235

    申请日：2006-11-17

    申请人： Kunio Yoneto ,  Katsuyuki Inoo

    发明人： Kunio Yoneto ,  Katsuyuki Inoo

    IPC分类号： A61K31/405 ,  A61K9/12

    CPC分类号： A61K31/405 ,  A61K9/7053 ,  A61K9/7061

    摘要： Methods of transdermally delivering a therapeutic amount of an indole serotonin receptor agonist to an individual in need thereof, e.g., to provide a therapeutic level of an indole serotonin receptor agonist to an individual in need thereof, are provided. Also provided are transdermal formulations of indole serotonin receptor agonists that find use in practicing the subject methods.

    摘要翻译： 提供了将治疗量的吲哚5-羟色胺受体激动剂透皮递送给有需要的个体的方法，例如向有需要的个体提供治疗水平的吲哚5-羟色胺受体激动剂。 还提供了可用于实践本发明方法的吲哚5-羟色胺受体激动剂的透皮制剂。

    Felbinac-containing external patch
    7.
    发明授权
    Felbinac-containing external patch 有权

    公开(公告)号：US09833417B2

    公开(公告)日：2017-12-05

    申请号：US13882747

    申请日：2011-11-01

    申请人： Katsuyuki Inoo

    发明人： Katsuyuki Inoo

    IPC分类号： A61K9/70 ,  A61K31/192

    CPC分类号： A61K9/7007 ,  A61K9/7053 ,  A61K31/192

    摘要： Provided is a felbinac-containing external patch which can exhibit high drug release properties, low skin irritation, and high drug stability, wherein felbinac having an average particle diameter of 5 μm or more and less than 100 μm is dispersed and mixed in an adhesive base including a styrene-isoprene-styrene block copolymer, an alicyclic saturated hydrocarbon resin, a softener, and diethyl sebacate, and does not contain L-menthol. Specifically, in the felbinac-containing external patch, 0.1 to 10% by weight of felbinac having an average particle diameter of 5 μm or more and less than 100 μm is dispersed and mixed in an adhesive base including 10 to 30% by weight of a styrene-isoprene-styrene block copolymer, 10 to 50% by weight of an alicyclic saturated hydrocarbon resin, 10 to 75% by weight of a softener, and 0.1 to 10% by weight of diethyl sebacate.

    Piroxicam-containing transdermally absorbable preparation
    9.
    发明授权
    Piroxicam-containing transdermally absorbable preparation 有权
    含吡罗昔康的经皮吸收制剂

    公开(公告)号：US09119861B2

    公开(公告)日：2015-09-01

    申请号：US13516014

    申请日：2010-12-14

    申请人： Akiko Katayama ,  Katsuyuki Inoo

    发明人： Akiko Katayama ,  Katsuyuki Inoo

    IPC分类号： A61K31/5415 ,  A61P29/00 ,  A61K31/245 ,  A61K9/70

    CPC分类号： A61K31/5415 ,  A61K9/7053 ,  A61K31/245 ,  A61K2300/00

    摘要： An adhesive patch is provided in which piroxicam is formulated as a non-steroidal anti-inflammatory analgesic. In particular, provided is a piroxicam-containing transdermally absorbable adhesive patch in which an absorption promoter to piroxicam is formulated to achieve high anti-inflammatory and analgesic effects without inhibiting releasing of these drugs. The piroxicam-containing transdermally absorbable adhesive patch contains piroxicam as a medicinal component and oxybuprocaine or a pharmaceutically acceptable salt thereof as an absorption promoter. In the piroxicam-containing transdermally absorbable adhesive patch, the content of piroxicam is from 0.1% to 5% by weight to the total weight of a drug-containing plaster and the content of oxybuprocaine or the pharmaceutically acceptable salt thereof is from 1% to 30% by weight to the total weight of the drug-containing plaster.

    摘要翻译： 提供了一种胶粘贴剂，其中吡罗昔康被配制成非甾体抗炎止痛剂。 特别地，提供了含有喜树毒素的透皮吸收性粘合贴剂，其中将吡罗昔康的吸收促进剂配制成达到高抗炎和止痛作用而不抑制这些药物的释放。 含有喜树碱的透皮吸收性粘合剂贴剂含有作为药物成分的吡罗昔康和作为吸收促进剂的氧麻黄碱或其药学上可接受的盐。 在含有喜树毒素的透皮吸收性贴剂中，炎痛喜树碱的含量相对于含药膏体的总重量为0.1〜5重量％，并且奥布卡因或其药学上可接受的盐的含量为1〜30 相对于含药膏药的总重量的重量百分比。