摘要:
The invention provides a universal linker capable of synthesizing nucleic acid having a phosphate group at the 3′ terminal, a universal support carrying the linker, and a synthesis method of nucleic acid using the universal support. The linker for solid phase synthesis of nucleic acid contains a compound represented by at least one of the following formulae wherein each symbol is as defined in the specification.
摘要:
The present invention provides porous resin beads containing an aromatic monovinyl compound-divinyl compound-(meth)acrylamide derivative copolymer. Preferably, the copolymer further contains as a structural unit a second aromatic monovinyl compound having a functional group capable of binding to a carboxyl group by a dehydrating condensation reaction.
摘要:
The present invention relates to a method for producing a porous resin particle containing an aromatic vinyl compound-aromatic divinyl compound copolymer having a hydroxyl group, the method including: dissolving a monomer mixture containing an aromatic vinyl compound, an aromatic divinyl compound and a (meth)acrylic acid ester having one hydroxyl group within the molecule thereof, and a polymerization initiator in an organic solvent to obtain a solution containing the monomer mixture and the polymerization initiator; suspending the solution in water in the presence of a dispersion stabilizer; and performing a suspension copolymerization. The method of the invention is capable of easily producing a porous resin particle containing an aromatic vinyl compound-aromatic divinyl compound copolymer having a hydroxyl group, that is used as a support for solid phase synthesis and enables efficient nucleic acid synthesis.
摘要:
The present invention provides a method for producing a porous resin bead containing an aromatic vinyl compound-hydroxystyrene-di(meth)acrylate copolymer, the method including: dissolving a monomer mixture containing an aromatic vinyl compound, an acyloxystyrene and a di(meth)acrylate compound, and a polymerization initiator in an organic solvent to obtain a solution containing the monomer mixture and the polymerization initiator; suspending the solution in water in the presence of a dispersion stabilizer; performing a suspension copolymerization to thereby obtain an aromatic vinyl compound-acyloxystyrene-di(meth)acrylate compound copolymer; and hydrolyzing an acyloxy group of the acyloxystyrene monomer component in the copolymer. The porous resin bead produced by the method of the present invention can be suitably used, for example, as a support for solid phase synthesis.
摘要:
The invention provides a universal linker capable of synthesizing nucleic acid having a phosphate group at the 3′ terminal, a universal support carrying the linker, and a synthesis method of nucleic acid using the universal support. The linker for solid phase synthesis of nucleic acid contains a compound represented by at least one of the following formulae wherein each symbol is as defined in the specification.
摘要:
The present invention provides a method for producing a porous resin bead containing an aromatic vinyl compound-hydroxystyrene-di(meth)acrylate copolymer, the method including: dissolving a monomer mixture containing an aromatic vinyl compound, an acyloxystyrene and a di(meth)acrylate compound, and a polymerization initiator in an organic solvent to obtain a solution containing the monomer mixture and the polymerization initiator; suspending the solution in water in the presence of a dispersion stabilizer; performing a suspension copolymerization to thereby obtain an aromatic vinyl compound-acyloxystyrene-di(meth)acrylate compound copolymer; and hydrolyzing an acyloxy group of the acyloxystyrene monomer component in the copolymer. The porous resin bead produced by the method of the present invention can be suitably used, for example, as a support for solid phase synthesis.
摘要:
The present invention provides, as a resin bead which can be developed for use completely different from the use of conventional polystyrene resin beads, a porous resin bead made from a styrene-hydroxystyrene-divinylbenzene copolymer, which contain a hydroxyl group in an amount of 10-1000 μmol/g, and further, a production method of a porous resin bead made from a styrene-hydroxystyrene-divinylbenzene copolymer, which contains suspension copolymerization of a styrene monomer, an acyloxystyrene monomer and a divinylbenzene monomer using an organic solvent (containing at least hydrocarbon and alcohol) and water, followed by hydrolysis reaction.
摘要:
The present invention relates to an immunological detection method capable of performing detection of an analyte in a test sample, and a kit used therefor. There is provided an immunological detection method for detecting an analyte by using a water-absorbent substrate in which a capture region is positioned in a given region on a surface thereof, the capture region being immobilized with a first immunochemical component capable of specifically binding to the analyte, wherein the detection signal is amplified and a kit used therefor.
摘要:
The present invention relates to a racing swimsuit and provides a racing swimsuit capable of reducing surface friction resistance and frictional resistance of turbulence in water. The present invention can reduce the surface frictional resistance in water by the provision of a water repellent region on the surface of a swimsuit as well as makes it possible to reduce the frictional resistance of turbulence occurred on the surface of the swimsuit of a racer by the formation of a plurality of fine grooves parallel to a body lengthwise direction.
摘要:
In a conferencing system comprising telephones and workstations to assist a cooperative work, a conference display control method for a visual user interface is provided. A conference window is displayed on a workstation display during execution of a teleconference. The conference window includes a meeting table area as a shared space and a local area which cannot be seen by the other participants. Document objects corresponding to a document application program which is used in the conference are arranged on those areas. The distribution of the documents, reference of information, and execution of the application program can be executed by direct manipulation of objects using a mouse. In the conference window, the document object can be operated at both the cooperative work place and the local work place. The operations during the conference can be simplified. Further, the conference window is displayed on the workstation display during the teleconference execution, the conference documents are sharingly executed by an OHP object on the conference window, and the documents during the shared execution are displayed in an OHP area, so that the kind of document which is being executed can be grasped.