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    Culture observation apparatus, sample tray heat-insulating device and lid
    1.
    发明申请
    Culture observation apparatus, sample tray heat-insulating device and lid 有权
    文化观察装置，样品托盘隔热装置和盖子

    公开(公告)号：US20060141609A1

    公开(公告)日：2006-06-29

    申请号：US11312114

    申请日：2005-12-20

    申请人： Akitsugu Kagayama ,  Ryuichi Hirano ,  Atsuhiro Tsuchiya ,  Kenichi Koyama ,  Kazuhiro Hasegawa ,  Katsuyoshi Yamaguchi ,  Hideaki Endo

    发明人： Akitsugu Kagayama ,  Ryuichi Hirano ,  Atsuhiro Tsuchiya ,  Kenichi Koyama ,  Kazuhiro Hasegawa ,  Katsuyoshi Yamaguchi ,  Hideaki Endo

    IPC分类号： C12M1/34

    CPC分类号： C12M23/48 ,  C12M23/50 ,  C12M41/12

    摘要： A culture observation apparatus, which is used for observing a cultured cell while culturing the cell, includes a culture device that forms a culture space which is controlled to be an environment suitable for culturing the cultured cell; a sample tray that holds a container housing the cultured cell and a culture medium; a microscope that serves for observing the cultured cell; a tray holding mechanism that holds the sample tray in the culture space in a detachable manner with good reproducibility; and a shifting mechanism that relatively shifts the sample tray held by the tray holding mechanism and a light axis of the microscope along a plane that is orthogonal to the light axis, wherein the sample tray has a heater used for heating the sample tray, and is electrically connectable to an energy supplying unit that supplies energy to the sample tray.

    摘要翻译： 用于在培养细胞时观察培养细胞的培养观察装置包括形成培养空间的培养装置，该培养装置被控制为适于培养培养细胞的环境; 容纳容纳培养细胞的容器和培养基的样品盘; 用于观察培养细胞的显微镜; 托盘保持机构，以可拆卸的方式将样品盘保持在培养空间中，具有良好的再现性; 以及移动机构，其使由所述托盘保持机构保持的所述检体托盘和所述显微镜的光轴沿着与所述光轴正交的平面相对移动，所述检体托盘具有用于加热所述检体托盘的加热器， 电连接到向样品托盘供应能量的能量供应单元。

    Culture observation apparatus, sample tray heat-insulating device and lid
    2.
    发明授权
    Culture observation apparatus, sample tray heat-insulating device and lid 有权
    文化观察装置，样品托盘隔热装置和盖子

    公开(公告)号：US07816126B2

    公开(公告)日：2010-10-19

    申请号：US11312114

    申请日：2005-12-20

    申请人： Akitsugu Kagayama ,  Ryuichi Hirano ,  Atsuhiro Tsuchiya ,  Kenichi Koyama ,  Kazuhiro Hasegawa ,  Katsuyoshi Yamaguchi ,  Hideaki Endo

    发明人： Akitsugu Kagayama ,  Ryuichi Hirano ,  Atsuhiro Tsuchiya ,  Kenichi Koyama ,  Kazuhiro Hasegawa ,  Katsuyoshi Yamaguchi ,  Hideaki Endo

    IPC分类号： C12M3/00 ,  C12M1/34

    CPC分类号： C12M23/48 ,  C12M23/50 ,  C12M41/12

    摘要： A culture observation apparatus, which is used for observing a cultured cell while culturing the cell, includes a culture device that forms a culture space which is controlled to be an environment suitable for culturing the cultured cell; a sample tray that holds a container housing the cultured cell and a culture medium; a microscope that serves for observing the cultured cell; a tray holding mechanism that holds the sample tray in the culture space in a detachable manner with good reproducibility; and a shifting mechanism that relatively shifts the sample tray held by the tray holding mechanism and a light axis of the microscope along a plane that is orthogonal to the light axis, wherein the sample tray has a heater used for heating the sample tray, and is electrically connectable to an energy supplying unit that supplies energy to the sample tray.

    摘要翻译： 用于在培养细胞时观察培养细胞的培养观察装置包括形成培养空间的培养装置，该培养装置被控制为适于培养培养细胞的环境; 容纳容纳培养细胞的容器和培养基的样品盘; 用于观察培养细胞的显微镜; 托盘保持机构，以可拆卸的方式将样品盘保持在培养空间中，具有良好的再现性; 以及移动机构，其使由所述托盘保持机构保持的所述检体托盘和所述显微镜的光轴沿着与所述光轴正交的平面相对移动，所述检体托盘具有用于加热所述检体托盘的加热器， 电连接到向样品托盘供应能量的能量供应单元。

    Observation apparatus
    3.
    发明授权
    Observation apparatus 有权
    观察装置

    公开(公告)号：US07595188B2

    公开(公告)日：2009-09-29

    申请号：US11302591

    申请日：2005-12-12

    申请人： Kazuhiro Hasegawa ,  Akitsugu Kagayama ,  Hideaki Endo ,  Ryuichi Hirano ,  Atsuhiro Tsuchiya ,  Kenichi Koyama ,  Katsuyoshi Yamaguchi

    发明人： Kazuhiro Hasegawa ,  Akitsugu Kagayama ,  Hideaki Endo ,  Ryuichi Hirano ,  Atsuhiro Tsuchiya ,  Kenichi Koyama ,  Katsuyoshi Yamaguchi

    IPC分类号： C12M3/00

    CPC分类号： C12M23/50 ,  C12M23/10 ,  C12M23/48 ,  C12M41/36

    摘要： An observation apparatus includes a sample tray that holds a container housing a cultured cell and a culture medium and covered with a lid; an observation unit that serves for observation of the cultured cell; and a shifting unit that relatively shifts the sample tray and a light axis of the observation unit along a plane that is orthogonal to the light axis of the observation unit, wherein the sample tray includes a container holding unit that holds the container by utilizing an elastic force, and at least one of the lid and one portion of the lid is made detachable, with the container being held in the sample tray by the container holding unit.

    摘要翻译： 观察装置包括：样本托盘，其容纳容纳培养细胞和培养基并容纳盖子的容器; 用于观察培养细胞的观察单元; 以及移动单元，其沿着与所述观察单元的光轴正交的平面相对地移动所述样本托盘和所述观察单元的光轴，其中，所述样本托盘包括容器保持单元，所述容器保持单元通过利用弹性 并且盖子和盖子的一部分中的至少一个是可拆卸的，容器通过容器保持单元保持在样品盘中。

    Culture observation apparatus
    4.
    发明授权
    Culture observation apparatus 有权
    文化观察仪器

    公开(公告)号：US07910355B2

    公开(公告)日：2011-03-22

    申请号：US11318416

    申请日：2005-12-22

    申请人： Atsuhiro Tsuchiya ,  Ryuichi Hirano ,  Hideaki Endo ,  Kenichi Koyama ,  Kazuhiro Hasegawa ,  Akitsugu Kagayama ,  Katsuyoshi Yamaguchi

    发明人： Atsuhiro Tsuchiya ,  Ryuichi Hirano ,  Hideaki Endo ,  Kenichi Koyama ,  Kazuhiro Hasegawa ,  Akitsugu Kagayama ,  Katsuyoshi Yamaguchi

    IPC分类号： C12M1/34 ,  C12M3/00 ,  G02B21/26 ,  G02B21/34 ,  G01N21/01

    CPC分类号： C12M41/36 ,  C12M41/14 ,  G02B7/22 ,  G02B21/0088 ,  G02B21/02

    摘要： A culture observation apparatus, which is used for observing a cultured cell while culturing the cell, includes a culture device that cultures the cultured cell, and a microscope used for observing the cultured cell. The culture device includes a first space that is controlled to an environment suitable for culture of the cell, and a second space that is controlled to a lower humidity condition in comparison with the first space. The microscope includes an objective optical unit including an objective lens; the objective optical unit having at least one portion located in the second space, and another portion extending into the first space through an opening formed in a partition wall that separates the first space and the second space, with a gap between the objective optical unit and the partition wall being sealed by a sealing member, and the objective lens includes a plurality of lens groups, with mutual spaces among the lens groups vented to the second space.

    摘要翻译： 用于在培养细胞时观察培养细胞的培养观察装置包括培养培养细胞的培养装置和用于观察培养细胞的显微镜。 培养装置包括被控制到适于细胞培养的环境的第一空间和与第一空间相比被控制到较低湿度条件的第二空间。 显微镜包括物镜光学单元，包括物镜; 所述物镜光学单元具有位于所述第二空间中的至少一个部分，以及另一部分，其通过形成在分隔所述第一空间和所述第二空间的分隔壁中的开口延伸到所述第一空间中，所述间隔物在所述物镜光学单元和 所述分隔壁由密封构件密封，并且所述物镜包括多个透镜组，所述透镜组中的彼此间隔开放到所述第二空间。

    Culture observation apparatus
    5.
    发明申请
    Culture observation apparatus 有权
    文化观察仪器

    公开(公告)号：US20060141613A1

    公开(公告)日：2006-06-29

    申请号：US11318416

    申请日：2005-12-22

    申请人： Atsuhiro Tsuchiya ,  Ryuichi Hirano ,  Hideaki Endo ,  Kenichi Koyama ,  Kazuhiro Hasegawa ,  Akitsugu Kagayama ,  Katsuyoshi Yamaguchi

    发明人： Atsuhiro Tsuchiya ,  Ryuichi Hirano ,  Hideaki Endo ,  Kenichi Koyama ,  Kazuhiro Hasegawa ,  Akitsugu Kagayama ,  Katsuyoshi Yamaguchi

    IPC分类号： C12M1/34 ,  G02B21/26 ,  G02B21/34

    CPC分类号： C12M41/36 ,  C12M41/14 ,  G02B7/22 ,  G02B21/0088 ,  G02B21/02

    摘要： A culture observation apparatus, which is used for observing a cultured cell while culturing the cell, includes a culture device that cultures the cultured cell, and a microscope used for observing the cultured cell. The culture device includes a first space that is controlled to an environment suitable for culture of the cell, and a second space that is controlled to a lower humidity condition in comparison with the first space. The microscope includes an objective optical unit including an objective lens; the objective optical unit having at least one portion located in the second space, and another portion extending into the first space through an opening formed in a partition wall that separates the first space and the second space, with a gap between the objective optical unit and the partition wall being sealed by a sealing member, and the objective lens includes a plurality of lens groups, with mutual spaces among the lens groups vented to the second space.

    摘要翻译： 用于在培养细胞时观察培养细胞的培养观察装置包括培养培养细胞的培养装置和用于观察培养细胞的显微镜。 培养装置包括被控制到适于细胞培养的环境的第一空间和与第一空间相比被控制到较低湿度条件的第二空间。 显微镜包括物镜光学单元，包括物镜; 所述物镜光学单元具有位于所述第二空间中的至少一个部分，以及另一部分，其通过形成在分隔所述第一空间和所述第二空间的分隔壁中的开口延伸到所述第一空间中，所述间隔物在所述物镜光学单元和 所述分隔壁由密封构件密封，并且所述物镜包括多个透镜组，所述透镜组中的彼此间隔开放到所述第二空间。

    Microscope and method of preventing dew condensation on objective lens
    9.
    发明授权
    Microscope and method of preventing dew condensation on objective lens 有权
    显微镜及防止物镜结露的方法

    公开(公告)号：US07382531B2

    公开(公告)日：2008-06-03

    申请号：US11259392

    申请日：2005-10-26

    申请人： Atsuhiro Tsuchiya ,  Katsuyoshi Yamaguchi ,  Akitsugu Kagayama ,  Kazuhiro Hasegawa ,  Hideaki Endo ,  Kenichi Koyama

    发明人： Atsuhiro Tsuchiya ,  Katsuyoshi Yamaguchi ,  Akitsugu Kagayama ,  Kazuhiro Hasegawa ,  Hideaki Endo ,  Kenichi Koyama

    IPC分类号： G02B21/26

    CPC分类号： G02B27/0006 ,  C12M41/12 ,  C12M41/36 ,  G02B7/008 ,  G02B21/30

    摘要： The problem to be solved by the present invention is to provide a microscope that prevents a dew condensation on an objective lens and allows obtaining a good microscopic image, and a method of preventing a dew condensation on an objective lens.A microscope includes an objective lens having a heater 22 in a cell incubator 3 having a high humidity space. The high humidity space is maintained at 90% to 100% of relative humidity and controlled to be at a predetermined gas temperature. A cultured cell 12 in the cell incubator 3 is observed via the objective lens 1, and the heater 22 is controlled to make the temperature of the objective lens 1 higher than the gas temperature of the high humidity space.

    摘要翻译： 本发明要解决的问题是提供一种防止物镜上的结露并且可以获得良好的显微图像的显微镜，以及防止物镜上的结露的方法。 显微镜包括在具有高湿度空间的细胞培养器3中具有加热器22的物镜。 高湿度空间保持在相对湿度的90％至100％，并被控制在预定的气体温度。 通过物镜1观察细胞培养器3中的培养细胞12，控制加热器22使物镜1的温度高于高湿度空间的气体温度。