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公开(公告)号：US08377470B2
公开(公告)日：2013-02-19
申请号：US13543244
申请日：2012-07-06
IPC分类号： A61K9/48
CPC分类号： A61K9/4816
摘要： A non-gelatin encapsulation system for liquid filled soft capsules, by nature of the carrier, the cationic-ionic balance of the carrier and the active ingredients, or the concentration of the active ingredients and excipients, are difficult or impossible to commercially encapsulate in gelatin capsules. In particular, the system is adapted for the encapsulation of highly basic, or alkaline, fills. The system provides for a predominantly starch and gelling carrageenan based shell, which displays high resistance to both concentrated fills and to alkaline fills, in particular, to those fills which contain the salt or salts of weak acids and strong bases.
摘要翻译： 用于液体填充的软胶囊的非明胶包封系统，由载体的性质，载体的阳离子离子平衡和活性成分，或活性成分和赋形剂的浓度，难以或不可能商业地包封在明胶中 胶囊。 特别地，该系统适用于高度碱性或碱性填料的包封。 该系统主要提供淀粉和胶凝角叉菜胶基壳，其显示出对浓缩填充物和碱性填料的高抗性，特别是含有弱酸和强碱的盐或盐的填料。
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公开(公告)号：US20120269889A1
公开(公告)日：2012-10-25
申请号：US13543244
申请日：2012-07-06
IPC分类号： A61K9/48 , A61K31/192 , A61K31/167
CPC分类号： A61K9/4816
摘要： A non-gelatin encapsulation system for liquid filled soft capsules, by nature of the carrier, the cationic-ionic balance of the carrier and the active ingredients, or the concentration of the active ingredients and excipients, are difficult or impossible to commercially encapsulate in gelatin capsules. In particular, the system is adapted for the encapsulation of highly basic, or alkaline, fills. The system provides for a predominantly starch and gelling carrageenan based shell, which displays high resistance to both concentrated fills and to alkaline fills, in particular, to those fills which contain the salt or salts of weak acids and strong bases.
摘要翻译： 用于液体填充的软胶囊的非明胶包封系统，由载体的性质，载体的阳离子离子平衡和活性成分，或活性成分和赋形剂的浓度，难以或不可能商业地包封在明胶中 胶囊。 特别地，该系统适用于高度碱性或碱性填料的包封。 该系统主要提供淀粉和胶凝角叉菜胶基壳，其显示出对浓缩填充物和碱性填料的高抗性，特别是含有弱酸和强碱的盐或盐的填料。
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公开(公告)号：US08231896B2
公开(公告)日：2012-07-31
申请号：US10984205
申请日：2004-11-08
IPC分类号： A61K9/48
CPC分类号： A61K9/4816
摘要： A non-gelatin encapsulation system for liquid filled soft capsules, by nature of the carrier, the cationic-ionic balance of the carrier and the active ingredients, or the concentration of the active ingredients and excipients, are difficult or impossible to commercially encapsulate in gelatin capsules. In particular, the system is adapted for the encapsulation of highly basic, or alkaline, fills. The system provides for a predominantly starch and gelling carrageenan based shell, which displays high resistance to both concentrated fills and to alkaline fills, in particular, to those fills which contain the salt or salts of weak acids and strong bases.
摘要翻译： 用于液体填充的软胶囊的非明胶包封系统，由载体的性质，载体的阳离子离子平衡和活性成分，或活性成分和赋形剂的浓度，难以或不可能商业地包封在明胶中 胶囊。 特别地，该系统适用于高度碱性或碱性填料的包封。 该系统主要提供淀粉和胶凝角叉菜胶基壳，其显示出对浓缩填充物和碱性填料的高抗性，特别是含有弱酸和强碱的盐或盐的填料。
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公开(公告)号：US20060099246A1
公开(公告)日：2006-05-11
申请号：US10984205
申请日：2004-11-08
IPC分类号： A61K9/48
CPC分类号： A61K9/4816
摘要： A non-gelatin encapsulation system for liquid filled soft capsules, by nature of the carrier, the cationic-ionic balance of the carrier and the active ingredients, or the concentration of the active ingredients and excipients, are difficult or impossible to commercially encapsulate in gelatin capsules. In particular, the system is adapted for the encapsulation of highly basic, or alkaline, fills. The system provides for a predominantly starch and gelling carrageenan based shell, which displays high resistance to both concentrated fills and to alkaline fills, in particular, to those fills which contain the salt or salts of weak acids and strong bases.
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5.发明授权Film forming compositions comprising modified starches and iota-carrageenan and methods for manufacturing soft capsules using same 有权包含改性淀粉和ι-角叉菜胶的成膜组合物以及使用其制备软胶囊的方法公开(公告)号：US06582727B2
公开(公告)日：2003-06-24
申请号：US10008694
申请日：2001-11-08
申请人： Keith Edward Tanner , John J. Getz , Stephen W. Burnett , Elizabeth Youngblood , Peter Robert Draper
发明人： Keith Edward Tanner , John J. Getz , Stephen W. Burnett , Elizabeth Youngblood , Peter Robert Draper
IPC分类号： A61K948
CPC分类号： A61K9/4816
摘要： Disclosed herein are composition comprising a modified starch and a carrageenan, especially iota-carrageenan, where the compositions are suitable for use in manufacturing soft capsules.
摘要翻译： 本文公开了包含改性淀粉和角叉菜胶，特别是ι-角叉菜胶的组合物，其中所述组合物适合用于制造软胶囊。
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公开(公告)号：USRE39079E1
公开(公告)日：2006-04-25
申请号：US10764382
申请日：2004-01-22
申请人： Keith Edward Tanner , Peter Robert Draper , John J. Getz , Stephen W. Burnett , Elizabeth Youngblood
发明人： Keith Edward Tanner , Peter Robert Draper , John J. Getz , Stephen W. Burnett , Elizabeth Youngblood
IPC分类号： A61K9/48
CPC分类号： A61K9/4816
摘要： Disclosed herein are compositions comprising a modified starch and a carrageenan, especially iota-carrageenan, where the compositions are suitable for use in manufacturing soft capsules.
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7.发明授权Film forming compositions comprising modified starches and iota-carrageenan and methods for manufacturing soft capsules using same 有权包含改性淀粉和ι-角叉菜胶的成膜组合物以及使用其制备软胶囊的方法公开(公告)号：US06340473B1
公开(公告)日：2002-01-22
申请号：US09608853
申请日：2000-06-30
申请人： Keith Edward Tanner , Peter Robert Draper , John J. Getz , Stephen W. Burnett , Elizabeth Youngblood
发明人： Keith Edward Tanner , Peter Robert Draper , John J. Getz , Stephen W. Burnett , Elizabeth Youngblood
IPC分类号： A61K948
CPC分类号： A61K9/4816
摘要： Disclosed herein are compositions comprising a modified starch and a carrageenan, especially iota-carrageenan, where the compositions are suitable for use in manufacturing soft capsules.
摘要翻译： 本文公开了包含改性淀粉和角叉菜胶，特别是ι-角叉菜胶的组合物，其中所述组合物适合用于制造软胶囊。
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