Method of ophthalmic testing
    3.
    发明授权
    Method of ophthalmic testing 失效
    眼科检测方法

    公开(公告)号:US5192665A

    公开(公告)日:1993-03-09

    申请号:US336249

    申请日:1989-04-11

    IPC分类号: A61K38/57 C12Q1/37

    CPC分类号: C12Q1/37 A61K38/57

    摘要: A method of determining the presence of epithelial lesions is provided wherein a sample of a body of fluid taken from an epithelial region suspected to have said lesions is tested for the presence of a proteolytic activity. The lesion is then treated by applying a therapeutically effective amount of a proteinase inhibitor in the form of a physiologically acceptable preparation, a pharmaceutical preparation of aprotinin being particularly preferred. A method for detecting allergic sensitivity is also disclosed.

    摘要翻译: 提供了确定上皮损伤存在的方法,其中测试从怀疑具有所述损伤的上皮区域获取的流体体的样品中存在蛋白水解活性。 然后通过以生理学上可接受的制剂的形式施用治疗有效量的蛋白酶抑制剂来治疗病变,特别优选抑肽酶的药物制剂。 还公开了一种用于检测过敏敏感性的方法。

    Diagnostic method, test kit, drug and therapeutic treatment for
autoimmune diseases
    4.
    发明授权
    Diagnostic method, test kit, drug and therapeutic treatment for autoimmune diseases 失效
    诊断方法,检测试剂盒,药物和治疗自身免疫性疾病

    公开(公告)号:US5700641A

    公开(公告)日:1997-12-23

    申请号:US396238

    申请日:1995-03-01

    IPC分类号: C12Q1/68 G01N33/564 G01N33/68

    摘要: Synthesized telomeric sequences bind to and can be used for detecting anti-DNA antibodies in serum. Autoimmune diseases such as Lupus Erythematosus, Rheumatoid Arthritis, and Scleroderma, can be detected by detecting an elevated level of anti-DNA antibodies using telomeric sequences. Test kits for such detection are provided including immobilized telomeric sequences capable of binding anti-DNA antibodies. Pharmaceutical compositions for inhibiting or reducing the activity of anti-DNA antibodies contain an effective amount of telomeric sequences effective in inhibiting the antibodies specific to the patient treated.

    摘要翻译: 合成的端粒序列结合并可用于检测血清中的抗DNA抗体。 可以通过使用端粒序列检测升高的抗DNA抗体水平来检测自身免疫疾病如狼疮红斑狼疮,类风湿关节炎和硬皮病。 提供了用于这种检测的测试试剂盒,包括能够结合抗DNA抗体的固定化端粒序列。 用于抑制或降低抗DNA抗体活性的药物组合物含有有效量的有效抑制被治疗患者特异性抗体的端粒序列。

    Pharmaceutical preparation for promoting epithelial healing and
prevention of epithelial destruction
    5.
    发明授权
    Pharmaceutical preparation for promoting epithelial healing and prevention of epithelial destruction 失效
    促进上皮愈合和预防上皮破坏的药物制剂

    公开(公告)号:US5112805A

    公开(公告)日:1992-05-12

    申请号:US336231

    申请日:1989-04-11

    IPC分类号: A61K38/57 C12Q1/37

    摘要: A method of determining the presence of epithelial lesions is provided wherein a sample of a body fluid taken from an epithelial region suspected to have said lesions is tested for the presence of a proteolytic activity. The lesion is then treated by applying a therapeutically effective amount of a proteinase inhibitor in the form of a physiologically acceptable preparation, a pharmaceutical preparation of aprotinin being particularly preferred.

    摘要翻译: 提供了确定上皮病变存在的方法,其中测试从怀疑具有所述损伤的上皮区域取得的体液样品的蛋白水解活性的存在。 然后通过以生理学上可接受的制剂的形式施用治疗有效量的蛋白酶抑制剂来治疗病变,特别优选抑肽酶的药物制剂。

    Method for promoting epithelial healing and prevention of epitheliam
destruction
    6.
    发明授权
    Method for promoting epithelial healing and prevention of epitheliam destruction 失效
    促进上皮愈合和预防上皮破坏的方法

    公开(公告)号:US4849406A

    公开(公告)日:1989-07-18

    申请号:US838339

    申请日:1986-03-11

    摘要: A method of determining the presence of epithelial lesions is provided wherein a sample of a body fluid taken from an epithelial region suspected to have said lesions is tested for the presence of a proteolytic activity. The lesion is then treated by applying a therapeutically effective amount of a proteinase inhibitor in the form of a physiologically acceptable preparation, a pharmaceutical preparation of aprotinin being particularly preferred.

    摘要翻译: 提供了确定上皮病变存在的方法,其中测试从怀疑具有所述损伤的上皮区域取得的体液样品的蛋白水解活性的存在。 然后通过以生理学上可接受的制剂的形式施用治疗有效量的蛋白酶抑制剂来治疗病变,特别优选抑肽酶的药物制剂。