公开(公告)号：US5468734A

公开(公告)日：1995-11-21

申请号：US368755

申请日：1995-01-04

申请人： Kenji Seri ,  Kazuko Sanai ,  Shigenori Negishi ,  Toshiro Akino

发明人： Kenji Seri ,  Kazuko Sanai ,  Shigenori Negishi ,  Toshiro Akino

IPC分类号： A23L1/307 ,  A23L1/09 ,  A61K31/70 ,  A61K31/7004 ,  A61K31/7016 ,  A61K31/715 ,  A61P3/04 ,  A61P3/08 ,  A61P3/10 ,  C07H3/02 ,  C07H3/04

CPC分类号： A61K31/7004 ,  Y10S514/824 ,  Y10S514/866 ,  Y10S514/909

摘要： A prophylactic and remedial preparation for a disease attendant on hyperglycemia, a preparation for depressing the rise in blood sugar, and a wholesome food separately include, as an active ingredient, at least one component selected from the group consisting of L-arabinose, L-fucose, 2-deoxy-D-galactose, D-xylose, L-xylose, D-ribose, D-tagatose, D-ribulose, D-lyxose and D-xylulose.

摘要翻译： 作为有效成分，含有高血糖的疾病的预防和补救制剂，分别抑制血糖升高的制剂和健康食品包括至少一种选自L-阿拉伯糖，L-赖氨酸， 岩藻糖，2-脱氧-D-半乳糖，D-木糖，L-木糖，D-核糖，D-塔格糖，D-核酮糖，D-赖索糖和D-木酮糖。

公开(公告)号：US20070293443A1

公开(公告)日：2007-12-20

申请号：US11659227

申请日：2005-08-04

申请人： Kazuko Sanai ,  Yuko Tanaka ,  Shigenori Negishi ,  Kenji Seri ,  Hironori Sasaki

发明人： Kazuko Sanai ,  Yuko Tanaka ,  Shigenori Negishi ,  Kenji Seri ,  Hironori Sasaki

IPC分类号： A61K31/7012 ,  A23C9/152 ,  C07H17/04 ,  C12P17/06 ,  A23L1/30

CPC分类号： A61K31/191 ,  A23L33/10 ,  A23L33/16 ,  A61K31/365

摘要： The present invention relates to a composition for accelerating calcium absorption containing a poorly absorbable L-form aldonic acid, a salt thereof, or a poorly absorbable L-form aldonolactone. The invention also relates to a food or beverage containing L-arabonic acid, a salt thereof, or L-arabonolactone. The invention also relates to a process for preparing L-arabono-γ-lactone crystals, characterized by dissolving L-arabonic acid in an organic solvent and crystallizing L-arabono-γ-lactone from the solution. According to the invention, a food or pharmaceutical product effective in the prevention or treatment of osteoporosis can be provided.

摘要翻译： 本发明涉及一种加速钙吸收的组合物，其中含有吸收不良的L型醛糖酸，其盐或吸收不良的L型醛糖内酯。 本发明还涉及含有L-阿拉伯糖，其盐或L-阿拉糖内酯的食品或饮料。 本发明还涉及制备L-阿拉伯糖-γ-内酯晶体的方法，其特征在于将L-阿拉伯糖溶解在有机溶剂中并从该溶液中结晶L-阿拉伯糖-γ-内酯。 根据本发明，可以提供有效预防或治疗骨质疏松症的食品或药物产品。

公开(公告)号：US4971985A

公开(公告)日：1990-11-20

申请号：US424129

申请日：1989-10-19

申请人： Katsuyuki Otsuka ,  Nobuo Ishiyama ,  Makoto Watanabe ,  Kenji Seri ,  Kazuko Sanai ,  Kanji Muraoka

发明人： Katsuyuki Otsuka ,  Nobuo Ishiyama ,  Makoto Watanabe ,  Kenji Seri ,  Kazuko Sanai ,  Kanji Muraoka

IPC分类号： A61K31/44 ,  A61K31/4402 ,  A61K31/4406 ,  A61K31/4409 ,  A61K31/4418 ,  A61K31/443 ,  A61K31/4433 ,  A61P9/08 ,  A61P9/10 ,  C07D213/53 ,  C07D405/06 ,  C07D409/06 ,  C07D409/12

CPC分类号： C07D213/53 ,  C07D409/12

摘要： A pyridylketoxime ether compound of the formula: ##STR1## wherein Ar is a phenyl, naphthyl, or heterocyclic group unsubstituted or substituted by a C.sub.1 -C.sub.8 alkyl group, a C.sub.1 -C.sub.8 alkylamino group, a C.sub.1 -C.sub.8 alkoxy group, a C.sub.1 -C.sub.8 alkoxycarbonyl group, a trifluoromethyl group, a nitro group or a halogen atom, X is a --(CH.sub.2).sub.m -- group wherein m is an integer of from 1 to 5, a --(CH.sub.2).sub.m --Y-- group wherein Y is an oxygen or sulfur atom and m is as defined above, or a --CH.sub.2 --(CH.dbd.CH).sub.n -- group wherein n is an integer of 1 or 2, and R is a phenyl, naphthyl, C.sub.3 -C.sub.8 cycloalkyl or heterocyclic group unsubstituted or substituted by a C.sub.1 -C.sub.8 alkyl group, a C.sub.1 -C.sub.8 alkylamino group, a C.sub.1 -C.sub.8 alkoxy group, a C.sub.1 -C.sub.8 akloxycarbonyl group, a trifluoromethyl group, a nitro group or a halogen atom, or a salt thereof.

公开(公告)号：US5095016A

公开(公告)日：1992-03-10

申请号：US562577

申请日：1990-08-03

申请人： Katuyuki Ohtuka ,  Nobuo Ishiyama ,  Yasuhito Iida ,  Kenji Seri ,  Takeshi Murai ,  Kazuko Sanai ,  Yoshihiro Ishizaka

发明人： Katuyuki Ohtuka ,  Nobuo Ishiyama ,  Yasuhito Iida ,  Kenji Seri ,  Takeshi Murai ,  Kazuko Sanai ,  Yoshihiro Ishizaka

IPC分类号： C07D311/58 ,  A61K31/35 ,  C07D311/68 ,  C07D311/70

CPC分类号： C07D311/70 ,  C07D311/68

摘要： A compound of the formula (I): ##STR1## or a pharmaceutically acceptable salt thereof, wherein: R.sup.1 is a hydrogen atom, a substituted or unsubstituted C.sub.1-6 alkyl group, a C.sub.2-6 alkenyl group, a C.sub.2-6 alkynyl group or a R.sup.7 --CO-- group (wherein R.sup.7 is a C.sub.1-6 alkyl group, a phenyl group, a C.sub.2-6 alkenyl group which may be substituted by a phenyl group, or a C.sub.1-6 alkoxy group);R.sup.2 is a hydrogen atom, a substituted or unsubstituted C.sub.1-8 alkyl group, or a phenyl group;R.sup.3 is a hydrogen atom, and R.sup.4 is a hydroxyl group, or R.sup.3 and R.sup.4 together form a bond;each of R.sup.5 and R.sup.6 is a C.sub.1-4 alkyl group; andY is a cyano group, a halogen atom, a nitro group, a C.sub.1-6 alkyl group, a C.sub.2-6 alkynyl group, a C.sub.1-6 alkylcarbonyl group, a C.sub.1-6 alkoxy group, a di-C.sub.1-6 alkylaminocarbonyl group, an aryl group, a C.sub.1-6 alkoxycarbonyl group, a carboxyl group or a morpholinocarbonyl group.

公开(公告)号：US20100227923A1

公开(公告)日：2010-09-09

申请号：US12161751

申请日：2007-01-30

申请人： Kazuko Sanai ,  Yuko Tanaka

发明人： Kazuko Sanai ,  Yuko Tanaka

IPC分类号： A61K31/19 ,  A61P13/02

CPC分类号： A61K31/365 ,  A23L33/10 ,  A61K31/191

摘要： The present invention relates to a prophylactic/therapeutic drug for urolithiasis containing as an active ingredient L-aldonic acid, a salt thereof, or a lactone form thereof.

摘要翻译： 本发明涉及含有L-阿糖醛酸，其盐或其内酯形式作为活性成分的尿石症的预防/治疗药物。