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公开(公告)号:US6096864A
公开(公告)日:2000-08-01
申请号:US7555
申请日:1998-01-15
IPC分类号: A61L15/44 , A61K38/00 , A61K38/07 , A61K38/08 , A61P43/00 , C07K5/103 , C07K14/78 , A61K38/04 , C07K5/00
CPC分类号: A61K38/07 , A61K38/08 , C07K14/78 , C07K5/1008
摘要: The invention provides wound treatment compositions comprising from 10.sup.-6 % to 1.0% w/w of one or more peptides, wherein the peptides are from 3 to 30 amino acid residues long and comprise the sequence Gly-Pro-Ala. Preferably, the peptides comprise the sequence Gly-Pro-Ala-Gly, more preferably at the N-terminus. The peptides exhibit a chemotactic effect towards fibroblasts.
摘要翻译: 本发明提供包含10-6%至1.0%w / w的一种或多种肽的伤口治疗组合物,其中肽长度为3至30个氨基酸残基并且包含Gly-Pro-Ala序列。 优选地,肽包含Gly-Pro-Ala-Gly序列,更优选在N-末端。 肽对成纤维细胞表现出趋化作用。