公开(公告)号：US07110816B2

公开(公告)日：2006-09-19

申请号：US10878953

申请日：2004-06-28

申请人： Kenneth L. Baker ,  David L. Perschbacher ,  Andrew P. Kramer ,  Jeffrey E. Stahmann

发明人： Kenneth L. Baker ,  David L. Perschbacher ,  Andrew P. Kramer ,  Jeffrey E. Stahmann

IPC分类号： A61N1/365

CPC分类号： A61N1/3627 ,  A61N1/3684

摘要： A device and method for improving tachyarrhythmia detection when the ventricles are resynchronized by delivering paces to both ventricles separated by a specified offset interval. Timing of escape intervals and tachyarrhythmia detection is based upon senses from one of the ventricles designated as a rate ventricle. A reversion pacing mode is provided in order to prevent tachyarrhythmia detection from being compromised when the rate ventricle is paced after the other ventricle.

公开(公告)号：US06757562B2

公开(公告)日：2004-06-29

申请号：US10037444

申请日：2001-10-25

申请人： Kenneth L. Baker ,  David L. Perschbacher ,  Andrew P. Kramer ,  Jeffrey E. Stahmann

发明人： Kenneth L. Baker ,  David L. Perschbacher ,  Andrew P. Kramer ,  Jeffrey E. Stahmann

IPC分类号： A61N1362

CPC分类号： A61N1/3627 ,  A61N1/3684

摘要： A device and method for improving tachyarrhythmia detection when the ventricles are resynchronized by delivering paces to both ventricles separated by a specified offset interval. Timing of escape intervals and tachyarrhythmia detection is based upon senses from one of the ventricles designated as a rate ventricle. A reversion pacing mode is provided in order to prevent tachyarrhythmia detection from being compromised when the rate ventricle is paced after the other ventricle.

摘要翻译： 通过向两个心室分配指定的偏移间隔来逐步重新同步心室，从而改善快速性心律失常检测的装置和方法。 逃避间隔和快速性心律失常检测的时间是基于指定为速率心室的心室之一的感觉。 提供回波起搏模式，以便当速率心室在另一脑室之后起搏时，防止快速性心律失常检测受到损害。

公开(公告)号：US07801609B2

公开(公告)日：2010-09-21

申请号：US11522691

申请日：2006-09-18

申请人： Kenneth L. Baker ,  David L. Perschbacher ,  Andrew P. Kramer ,  Jeffrey E. Stahmann

发明人： Kenneth L. Baker ,  David L. Perschbacher ,  Andrew P. Kramer ,  Jeffrey E. Stahmann

IPC分类号： A61N1/00

CPC分类号： A61N1/3627 ,  A61N1/3684

摘要： A device and method for improving tachyarrhythmia detection when the ventricles are resynchronized by delivering paces to both ventricles separated by a specified offset interval. Timing of escape intervals and tachyarrhythmia detection is based upon senses from one of the ventricles designated as a rate ventricle. A reversion pacing mode is provided in order to prevent tachyarrhythmia detection from being compromised when the rate ventricle is paced after the other ventricle.

摘要翻译： 通过向两个心室分配指定的偏移间隔来逐步重新同步心室，从而改善快速性心律失常检测的装置和方法。 逃避间隔和快速性心律失常检测的时间是基于指定为速率心室的心室之一的感觉。 提供回波起搏模式，以便当速率心室在另一脑室之后起搏时，防止快速性心律失常检测受到损害。

公开(公告)号：US06427084B2

公开(公告)日：2002-07-30

申请号：US09514813

申请日：2000-02-28

申请人： Kenneth L. Baker ,  Doug M. Birkholz ,  David L. Perschbacher ,  Andrew P. Kramer ,  Gary T. Seim

发明人： Kenneth L. Baker ,  Doug M. Birkholz ,  David L. Perschbacher ,  Andrew P. Kramer ,  Gary T. Seim

IPC分类号： A61N1362

CPC分类号： A61N1/368 ,  A61N1/3622 ,  A61N1/3684

摘要： A hybrid cardiac pacemaker in which the operation of the device is controlled by hardware-based controller as supervised by a microprocessor-based controller. The hardware-based controller comprises a plurality of timers that expire when they reach timer limit values stored in registers updatable by the microprocessor, and a combinational logic array for causing the device to generate pace outputs in accordance with timer expirations and sense signals. The combinational logic array may operate the pacemaker in a number of programmed modes in accordance with a mode value stored in a mode control register by the microprocessor.

摘要翻译： 一种混合心脏起搏器，其中由基于微处理器的控制器监控的由基于硬件的控制器控制该设备的操作。 基于硬件的控制器包括多个定时器，当它们达到存储在可由微处理器更新的寄存器中的定时器限制值时，该定时器到期，以及组合逻辑阵列，用于使该设备根据定时器期满和感测信号产生步进输出。 组合逻辑阵列可以根据由微处理器存储在模式控制寄存器中的模式值，以多种编程模式操作起搏器。

公开(公告)号：US06920355B2

公开(公告)日：2005-07-19

申请号：US10150297

申请日：2002-05-17

申请人： Kenneth L. Baker ,  Doug M. Birkholz ,  David L. Perschbacher ,  Andrew P. Kramer ,  Gary T. Seim

发明人： Kenneth L. Baker ,  Doug M. Birkholz ,  David L. Perschbacher ,  Andrew P. Kramer ,  Gary T. Seim

IPC分类号： A61N1/362 ,  A61N1/368

CPC分类号： A61N1/368 ,  A61N1/3622 ,  A61N1/3684

摘要： A hybrid cardiac pacemaker in which the operation of the device is controlled by hardware-based controller as supervised by a microprocessor-based controller. The hardware-based controller comprises a plurality of timers that expire when they reach timer limit values stored in registers updatable by the microprocessor, and a combinational logic array for causing the device to generate pace outputs in accordance with timer expirations and sense signals. The combinational logic array may operate the pacemaker in a number of programmed modes in accordance with a mode value stored in a mode control register by the microprocessor.

摘要翻译： 一种混合心脏起搏器，其中由基于微处理器的控制器监控的由基于硬件的控制器控制该设备的操作。 基于硬件的控制器包括多个定时器，当它们达到存储在可由微处理器更新的寄存器中的定时器限制值时，该定时器到期，以及组合逻辑阵列，用于使该设备根据定时器期满和感测信号产生步进输出。 组合逻辑阵列可以根据由微处理器存储在模式控制寄存器中的模式值，以多种编程模式操作起搏器。

公开(公告)号：US06285907B1

公开(公告)日：2001-09-04

申请号：US09316588

申请日：1999-05-21

申请人： Andrew P. Kramer ,  Jeffrey E. Stahmann ,  Rene H. Wentkowski ,  Kenneth L. Baker ,  Jesse W. Hartley ,  David B. Krig

发明人： Andrew P. Kramer ,  Jeffrey E. Stahmann ,  Rene H. Wentkowski ,  Kenneth L. Baker ,  Jesse W. Hartley ,  David B. Krig

IPC分类号： A61N1365

CPC分类号： A61N1/3621 ,  A61N1/3627 ,  A61N1/3682 ,  A61N1/395 ,  A61N1/3962 ,  A61N1/3987

摘要： A cardiac rhythm management system includes techniques for computing an indicated pacing interval, AV delay, or other timing interval. In one embodiment, a variable indicated pacing interval is computed based at least in part on an underlying intrinsic heart rate. The indicated pacing interval is used to time the delivery of biventricular coordination therapy even when ventricular heart rates are irregular, such as in the presence of atrial fibrillation. In another embodiment, a variable filter indicated AV interval is computed based at least in part on an underlying intrinsic AV interval. The indicated AV interval is used to time the delivery of atrial tracking biventricular coordination therapy when atrial heart rhythms are not arrhythmic. Other indicated timing intervals may be similarly determined. The indicated pacing interval, AV delay, or other timing interval can also be used in combination with a sensor indicated rate indicator.

公开(公告)号：US06411848B1

公开(公告)日：2002-06-25

申请号：US09837019

申请日：2001-04-18

申请人： Andrew P. Kramer ,  Jeffrey E. Stahmann ,  Rene H. Wentkowski ,  Kenneth L. Baker ,  Jesse W. Hartley ,  David B. Krig

发明人： Andrew P. Kramer ,  Jeffrey E. Stahmann ,  Rene H. Wentkowski ,  Kenneth L. Baker ,  Jesse W. Hartley ,  David B. Krig

IPC分类号： A61N1365

摘要： A cardiac rhythm management system includes techniques for computing an indicated pacing interval, AV delay, or other timing interval. In one embodiment, a variable indicated pacing interval is computed based at least in part on an underlying intrinsic heart rate. The indicated pacing interval is used to time the delivery of biventricular coordination therapy even when ventricular heart rates are irregular, such as in the presence of atrial fibrillation. In another embodiment, a variable filter indicated AV interval is computed based at least in part on an underlying intrinsic AV interval. The indicated AV interval is used to time the delivery of atrial tracking biventricular coordination therapy when atrial heart rhythms are not arrhythmic. Other indicated timing intervals may be similarly determined. The indicated pacing interval, AV delay, or other timing interval can also be used in combination with a sensor indicated rate indicator.

公开(公告)号：US20120150250A1

公开(公告)日：2012-06-14

申请号：US13397115

申请日：2012-02-15

申请人： Imad Libbus ,  Andrew P. Kramer ,  William J. Linder ,  Jeffrey E. Stahmann

发明人： Imad Libbus ,  Andrew P. Kramer ,  William J. Linder ,  Jeffrey E. Stahmann

IPC分类号： A61N1/362 ,  A61N1/39

CPC分类号： A61N1/37 ,  A61N1/36114 ,  A61N1/36125 ,  A61N1/362 ,  A61N1/36514 ,  A61N1/36564 ,  A61N1/36592 ,  A61N1/3987

摘要： Various aspects relate to a method. In various embodiments, a therapy of a first therapy type is delivered, and it is identified whether a therapy of a second therapy type is present to affect the therapy of the first therapy type. Delivery of the therapy is controlled based on the presence of the therapy of the second therapy type. Some embodiments deliver the therapy of the first type using one set of parameters in the presence of a therapy of a second type, and deliver the therapy of the first type using another set of parameters when the therapy of the second type is not present. In various embodiments, one of the therapy types includes a cardiac rhythm management therapy, and the other includes a neural stimulation therapy. Other aspects and embodiments are provided herein.

摘要翻译： 各方面涉及一种方法。 在各种实施方案中，递送第一疗法类型的治疗，并且确定是否存在第二疗法类型的治疗以影响第一疗法类型的治疗。 基于第二疗法类型的治疗的存在来控制治疗的递送。 一些实施例在存在第二类型的治疗的情况下使用一组参数递送第一类型的治疗，并且当不存在第二类型的治疗时，使用另一组参数递送第一类型的治疗。 在各种实施例中，治疗类型中的一种包括心律管理疗法，另一种包括神经刺激疗法。 本文提供了其它方面和实施例。

公开(公告)号：US08131359B2

公开(公告)日：2012-03-06

申请号：US12148843

申请日：2008-04-23

申请人： Imad Libbus ,  Andrew P. Kramer ,  William J. Linder ,  Jeffrey E. Stahmann

发明人： Imad Libbus ,  Andrew P. Kramer ,  William J. Linder ,  Jeffrey E. Stahmann

IPC分类号： A61N1/05

CPC分类号： A61N1/37 ,  A61N1/36114 ,  A61N1/36125 ,  A61N1/362 ,  A61N1/36514 ,  A61N1/36564 ,  A61N1/36592 ,  A61N1/3987

摘要： Various aspects relate to a method. In various embodiments, a therapy of a first therapy type is delivered, and it is identified whether a therapy of a second therapy type is present to affect the therapy of the first therapy type. Delivery of the therapy is controlled based on the presence of the therapy of the second therapy type. Some embodiments deliver the therapy of the first type using one set of parameters in the presence of a therapy of a second type, and deliver the therapy of the first type using another set of parameters when the therapy of the second type is not present. In various embodiments, one of the therapy types includes a cardiac rhythm management therapy, and the other includes a neural stimulation therapy. Other aspects and embodiments are provided herein.

摘要翻译： 各方面涉及一种方法。 在各种实施方案中，递送第一疗法类型的治疗，并且确定是否存在第二疗法类型的治疗以影响第一疗法类型的治疗。 基于第二疗法类型的治疗的存在来控制治疗的递送。 一些实施例在存在第二类型的治疗的情况下使用一组参数递送第一类型的治疗，并且当不存在第二类型的治疗时，使用另一组参数递送第一类型的治疗。 在各种实施例中，治疗类型中的一种包括心律管理疗法，另一种包括神经刺激疗法。 本文提供了其它方面和实施例。

公开(公告)号：US20120029588A1

公开(公告)日：2012-02-02

申请号：US13273108

申请日：2011-10-13

申请人： Andrew P. Kramer ,  Joseph M. Pastore ,  Jeffrey E. Stahmann ,  Rodney W. Salo ,  Jesse W. Hartley

发明人： Andrew P. Kramer ,  Joseph M. Pastore ,  Jeffrey E. Stahmann ,  Rodney W. Salo ,  Jesse W. Hartley

IPC分类号： A61N1/365

CPC分类号： A61N1/36557 ,  A61B5/6816 ,  A61B5/6826 ,  A61B5/6829 ,  A61B5/6838 ,  A61N1/36114 ,  A61N1/36564

摘要： A cardiac rhythm management (CRM) system includes a non-invasive hemodynamic sensing device and an implantable medical device to sense a hemodynamic signal and derive one or more cardiac performance parameters from the hemodynamic signal. The non-invasive hemodynamic sensing device includes at least a portion configured for external attachment to a body in which the implantable medical device is implanted. The one or more cardiac performance parameters are used for various diagnostic, monitoring, and therapy control purposes.

摘要翻译： 心律管理（CRM）系统包括非侵入性血液动力学感测装置和可植入医疗装置，用于感测血液动力学信号并从血流动力学信号导出一个或多个心脏性能参数。 非侵入式血流动力学检测装置包括至少一部分，其构造成用于外部附接到其中植入可植入医疗装置的主体。 一个或多个心脏性能参数用于各种诊断，监测和治疗控制目的。