公开(公告)号：US20120065741A1

公开(公告)日：2012-03-15

申请号：US12880502

申请日：2010-09-13

申请人： Chao-Fu Chang ,  Kent Kuohua Chang

发明人： Chao-Fu Chang ,  Kent Kuohua Chang

IPC分类号： A61F2/02

CPC分类号： A61C8/0006 ,  A61L31/005 ,  A61L31/146

摘要： A guided tissue regeneration membrane has a top surface, a bottom surface and a plurality of through holes formed through the top and bottom surfaces. Each of the plurality of through holes has a base opening on the top surface and a tip opening on the bottom surface. The diameter of the base opening is larger than that of the tip opening. The guided tissue regeneration membrane is placed between a hard tissue and a soft tissue of gums with the top surface thereof facing the hard tissue so as to hinder the soft tissue from rapidly growing. The tip openings are available for the soft tissue to supply nutrient to the hard tissue therethrough. The hard tissue can grow from the base openings, through the corresponding through holes and to the soft tissue to repair periodontal tissue.

摘要翻译： 引导组织再生膜具有顶表面，底表面和穿过顶表面和底表面形成的多个通孔。 多个通孔中的每一个在顶表面上具有基部开口，在底面上具有顶端开口。 基座开口的直径大于顶端开口的直径。 引导组织再生膜置于硬组织和牙龈软组织之间，其顶表面面向硬组织，以阻止软组织迅速生长。 尖端开口可用于软组织，以通过其中的硬组织提供营养。 硬组织可以从基底开口，通过相应的通孔和软组织生长，以修复牙周组织。

公开(公告)号：US20120065604A1

公开(公告)日：2012-03-15

申请号：US12880424

申请日：2010-09-13

申请人： Chao-Fu Chang ,  Kent Kuohua Chang

发明人： Chao-Fu Chang ,  Kent Kuohua Chang

IPC分类号： A61L15/64 ,  B29C44/00 ,  A61F13/36 ,  B29C44/04

CPC分类号： B29C44/348 ,  A61F13/36 ,  A61F2013/00221 ,  A61F2013/00463 ,  A61L24/0042 ,  A61L24/0084 ,  A61L24/043 ,  A61L2400/04 ,  C08L67/04

摘要： A degradable hemostatic sponge that can be self-degraded and absorbed by a human body has poly lactic acid as its main material and mixed with a moisture-absorbent material, such as collagen, chitosan, starch and the like, at a specific ratio. Given grinding, mixing and melting steps, the materials using a supercritical fluid as a foaming agent can be used to manufacture the degradable hemostatic sponge having an open-cell microcellular form by a continuous extrusion foaming process. In addition, the present invention also includes a system and a method for manufacturing the degradable hemostatic sponge.

摘要翻译： 可以自身降解并被人体吸收的可降解止血海绵以聚乳酸为主要原料，并以特定的比例与胶原，壳聚糖，淀粉等吸湿材料混合。 考虑到研磨，混合和熔融步骤，使用超临界流体作为发泡剂的材料可用于通过连续挤出发泡方法制造具有开孔细胞微孔形式的可降解止血海绵。 此外，本发明还包括用于制造可降解止血海绵的系统和方法。

公开(公告)号：US20140080096A1

公开(公告)日：2014-03-20

申请号：US14055718

申请日：2013-10-16

申请人： Kent Kuohua Chang

发明人： Chao-Fu Chang ,  Kent Kuohua Chang

IPC分类号： A61C8/02

CPC分类号： A61C8/0006 ,  A61L31/088 ,  A61L31/146 ,  A61L2400/12

摘要： A guided tissue regeneration membrane has a top surface, a bottom surface and the two surfaces are characterized by the plurality of through conical holes. Each of the plurality of through holes has a base opening on the top surface and a tip opening on the bottom surface. The diameter of the base opening is larger than that of the tip opening The guided tissue regeneration membrane is placed between a hard tissue and a soft tissue of gums with the top surface thereof facing the hard tissue so as to hinder the soft tissue from rapidly growing. The tip openings are available for the soft tissue to supply nutrient to the hard tissue therethrough. The hard tissue can grow from the base openings, through the corresponding through holes and to the soft tissue to repair periodontal tissue. In order to achieve a better affinity for cell growth, the guided tissue membrane surface facing the bony surface is coated with a hydrophilic, bioactive and biocompatible nano scaled oxidation layer.

摘要翻译： 引导组织再生膜具有顶表面，底表面，两个表面的特征在于多个通孔。 多个通孔中的每一个在顶表面上具有基部开口，在底面上具有顶端开口。 基部开口的直径大于尖端开口的直径引导的组织再生膜被放置在硬组织和牙龈的软组织之间，其顶表面面向硬组织，从而阻碍软组织快速生长 。 尖端开口可用于软组织，以通过其中的硬组织提供营养。 硬组织可以从基底开口，通过相应的通孔和软组织生长，以修复牙周组织。 为了实现对细胞生长的更好的亲和力，面向骨表面的引导组织膜表面涂覆有亲水的，生物活性的和生物相容的纳米级氧化层。