-
公开(公告)号:US20120027773A1
公开(公告)日:2012-02-02
申请号:US13177071
申请日:2011-07-06
申请人: Kerry Whalen , Steve Botega , Andrea Boudrow , Lyne Breault , Ting Chen , James Gifford , May Han , Jinwei Jiang , Lorena Lerner , Qing Liu , Kristan Meetze , Sylvie Vincent , Solly Weiler , William M. Winston, JR. , Jeno Gyuris
发明人: Kerry Whalen , Steve Botega , Andrea Boudrow , Lyne Breault , Ting Chen , James Gifford , May Han , Jinwei Jiang , Lorena Lerner , Qing Liu , Kristan Meetze , Sylvie Vincent , Solly Weiler , William M. Winston, JR. , Jeno Gyuris
IPC分类号: A61K39/395 , C12N15/13 , C12N15/63 , A61P35/00 , C12N1/21 , C12P21/00 , C12N5/09 , C07K16/40 , C12N5/10
CPC分类号: C07K16/30 , A61K2039/505 , C07K16/2896 , C07K2317/24 , C07K2317/73 , C07K2317/76 , C07K2317/77 , C07K2317/92
摘要: Monoclonal antibodies that bind and inhibit activation of human RON (Recepteur d' Origine Nantais) are disclosed. The antibodies can be used to treat certain forms of cancer that are associated with activation of RON.
摘要翻译: 公开了结合并抑制人RON(Recepteur d'Origine Nantais)活化的单克隆抗体。 抗体可用于治疗与RON活化相关的特定形式的癌症。
-
公开(公告)号:US08603478B2
公开(公告)日:2013-12-10
申请号:US13177071
申请日:2011-07-06
申请人: Kerry Whalen , Steve Bottega , Andrea Boudrow , Lyne Breault , Ting Chen , James Gifford , May Han , Jinwei Jiang , Lorena Lerner , Qing Liu , Kristan Meetze , Sylvie Vincent , Solly Weiler , William M. Winston, Jr. , Jeno Gyuris
发明人: Kerry Whalen , Steve Bottega , Andrea Boudrow , Lyne Breault , Ting Chen , James Gifford , May Han , Jinwei Jiang , Lorena Lerner , Qing Liu , Kristan Meetze , Sylvie Vincent , Solly Weiler , William M. Winston, Jr. , Jeno Gyuris
IPC分类号: A61K39/395
CPC分类号: C07K16/30 , A61K2039/505 , C07K16/2896 , C07K2317/24 , C07K2317/73 , C07K2317/76 , C07K2317/77 , C07K2317/92
摘要: Monoclonal antibodies that bind and inhibit activation of human RON (Recepteur d' Origine Nantais) are disclosed. The antibodies can be used to treat certain forms of cancer that are associated with activation of RON.
摘要翻译: 公开了结合并抑制人RON(Recepteur d'Origine Nantais)活化的单克隆抗体。 抗体可用于治疗与RON活化相关的特定形式的癌症。
-