公开(公告)号：US10077297B2

公开(公告)日：2018-09-18

申请号：US15552065

申请日：2016-02-19

Applicant: Kissei Pharmaceutical Co., Ltd.

Inventor： Takashi Sakamoto ,  Yoichi Inada ,  Kazumasa Yokoyama

IPC: A61K39/00 ,  C07K14/735

CPC classification number: C07K14/70535 ,  A61K38/16 ,  C07K14/705 ,  C07K16/18 ,  C07K19/00 ,  C07K2319/30 ,  C12N15/09

Abstract: Provided is an Fc fusion high affinity IgE receptor α-chain having excellent stability at low pH.An Fc fusion protein comprising: (i) a high affinity IgE receptor α-chain; and (ii) an Fc region of IgG1, wherein a linker fragment region between the (i) and the (ii) is the amino acid sequence shown in SEQ ID NO: 2.

公开(公告)号：US10047139B2

公开(公告)日：2018-08-14

申请号：US15552065

申请日：2016-02-19

Applicant: Kissei Pharmaceutical Co., Ltd.

Inventor： Takashi Sakamoto ,  Yoichi Inada ,  Kazumasa Yokoyama

IPC: A61K39/00 ,  C07K14/735

Abstract: Provided is an Fc fusion high affinity IgE receptor α-chain having excellent stability at low pH.An Fc fusion protein comprising: (i) a high affinity IgE receptor α-chain; and (ii) an Fc region of IgG1, wherein a linker fragment region between the (i) and the (ii) is the amino acid sequence shown in SEQ ID NO: 2.

公开(公告)号：US20180312566A1

公开(公告)日：2018-11-01

申请号：US16034648

申请日：2018-07-13

Applicant: Kissei Pharmaceutical Co., Ltd.

Inventor： Takashi Sakamoto ,  Yoichi Inada ,  Kazumasa Yokoyama

IPC: C07K14/735 ,  C12N15/09 ,  A61K38/16 ,  C07K16/18 ,  C07K14/705 ,  C07K19/00

CPC classification number: C07K14/70535 ,  A61K38/16 ,  C07K14/705 ,  C07K16/18 ,  C07K19/00 ,  C07K2319/30 ,  C12N15/09

Abstract: Provided is an Fc fusion high affinity IgE receptor α-chain having excellent stability at low pH. An Fc fusion protein comprising: (i) a high affinity IgE receptor α-chain; and (ii) an Fc region of IgG1, wherein a linker fragment region between the (i) and the (ii) is the amino acid sequence shown in SEQ ID NO: 2.

公开(公告)号：US20180044402A1

公开(公告)日：2018-02-15

申请号：US15552065

申请日：2016-02-19

Applicant: Kissei Pharmaceutical Co., Ltd.

Inventor： Takashi Sakamoto ,  Yoichi INADA ,  Kazumasa YOKOYAMA

IPC: C07K14/735

CPC classification number: C07K14/70535 ,  A61K38/16 ,  C07K14/705 ,  C07K16/18 ,  C07K19/00 ,  C07K2319/30 ,  C12N15/09

Abstract: Provided is an Fc fusion high affinity IgE receptor α-chain having excellent stability at low pH.An Fc fusion protein comprising: (i) a high affinity IgE receptor α-chain; and (ii) an Fc region of IgG1, wherein a linker fragment region between the (i) and the (ii) is the amino acid sequence shown in SEQ ID NO: 2.