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公开(公告)号：US06767742B1
公开(公告)日：2004-07-27
申请号：US09358321
申请日：1999-07-21
IPC分类号： C12N1582
CPC分类号： C12N9/0083 , C07K16/40 , C07K2317/13 , C07K2317/622 , C12N15/8258 , C12N2799/026
摘要： Monoclonal antibodies expressed in plant cells bind targeted transit peptides to decrease steady state levels of passenger proteins in plant organelles.
摘要翻译： 在植物细胞中表达的单克隆抗体结合靶向转运肽，以降低植物细胞器中游离蛋白的稳态水平。
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公开(公告)号：US06717035B2
公开(公告)日：2004-04-06
申请号：US10435835
申请日：2003-05-12
申请人： James K. Petell , Donald J. Merlo , Rod A. Herman , Jean L. Roberts , Lining Guo , Barry W. Schafer , Kitisri Sukhapinda , Ann Owens Merlo
发明人： James K. Petell , Donald J. Merlo , Rod A. Herman , Jean L. Roberts , Lining Guo , Barry W. Schafer , Kitisri Sukhapinda , Ann Owens Merlo
IPC分类号： A01H500
CPC分类号： C07K14/24 , C12N15/8286 , Y02A40/162
摘要： Novel polynucleotide sequences that encode insect toxins TcdA and TcbA have base compositions that differ substantially from the native genes, making them more similar to plant genes. The new sequences are suitable for use for high expression in both monocots and dicots. Transgenic plants with a genome comprising the nucleic acid of SEQ ID NO:4 are insect resistant.
摘要翻译： 编码昆虫毒素TcdA和TcbA的新型多核苷酸序列具有与天然基因显着不同的基本组成，使得它们与植物基因更相似。 新的序列适用于单子叶植物和双子叶植物中的高表达。 具有包含SEQ ID NO：4的核酸的基因组的转基因植物具有抗虫性。
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公开(公告)号：US06590142B1
公开(公告)日：2003-07-08
申请号：US09637048
申请日：2000-08-11
申请人： James K. Petell , Donald J. Merlo , Rod A. Herman , Jean L. Roberts , Lining Guo , Barry W. Schafer , Kitisri Sukhapinda , Ann Owens Merlo
发明人： James K. Petell , Donald J. Merlo , Rod A. Herman , Jean L. Roberts , Lining Guo , Barry W. Schafer , Kitisri Sukhapinda , Ann Owens Merlo
IPC分类号： A01H500
CPC分类号： C07K14/24 , C12N15/8286 , Y02A40/162
摘要： Novel polynucleotide sequences that encode insect toxins TcdA and TcbA have base compositions that differ substantially from the native genes, making them more similar to plant genes. The new sequences are suitable for use for high expression in both monocots and dicots. Transgenic plants with a genome comprising a nucleic acid of SEQ ID NO: 3 or SEQ ID NO:4 are insect resistant.
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公开(公告)号：US06528484B1
公开(公告)日：2003-03-04
申请号：US08851567
申请日：1997-05-05
申请人： Jerald C. Ensign , David J. Bowen , James Petell , Raymond Fatig , Sue Schoonover , Richard H. ffrench-Constant , Thomas A. Rocheleau , Michael B. Blackburn , Timothy D. Hey , Donald J. Merlo , Gregory L. Orr , Jean L. Roberts , James A. Strickland , Lining Guo , Todd A. Ciche , Kitisri Sukhapinda
发明人： Jerald C. Ensign , David J. Bowen , James Petell , Raymond Fatig , Sue Schoonover , Richard H. ffrench-Constant , Thomas A. Rocheleau , Michael B. Blackburn , Timothy D. Hey , Donald J. Merlo , Gregory L. Orr , Jean L. Roberts , James A. Strickland , Lining Guo , Todd A. Ciche , Kitisri Sukhapinda
IPC分类号： A01N3718
CPC分类号： C07K14/24 , A01N63/02 , C07K14/195 , C12N9/52 , C12N15/8286 , Y02A40/162
摘要： Proteins from the genus Photorhabdus are toxic to insects upon exposure. Photorhabdus luminescens (formerly Xenorhabdus luminescens) have been found in mammalian clinical samples and as a bacterial symbiont of entomopathogenic nematodes of genus Heterorhabditis. These protein toxins can be applied to, or genetically engineered into, insect larvae food and plants for insect control.
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公开(公告)号：US07569748B2
公开(公告)日：2009-08-04
申请号：US10262794
申请日：2002-10-02
申请人： Jerald C. Ensign , David J. Bowen , James Petell , Raymond Fatig , Sue Schoonover , Richard H. Ffrench-Constant , Thomas A. Rocheleau , Michael B. Blackburn , Timothy D. Hey , Donald J. Merlo , Gregory L Orr , Jean L. Roberts , James A. Strickland , Lining Guo , Todd A. Ciche , Kitisri Sukhapinda
发明人： Jerald C. Ensign , David J. Bowen , James Petell , Raymond Fatig , Sue Schoonover , Richard H. Ffrench-Constant , Thomas A. Rocheleau , Michael B. Blackburn , Timothy D. Hey , Donald J. Merlo , Gregory L Orr , Jean L. Roberts , James A. Strickland , Lining Guo , Todd A. Ciche , Kitisri Sukhapinda
CPC分类号： A01N63/02 , C07K14/195 , C07K14/24 , C12N9/52 , C12N15/8286 , Y02A40/162
摘要： Proteins from the genus Photorhabdus are toxic to insects upon exposure. Photorhabdus luminescens (formerly Xenorhabdus luminescens) have been found in mammalian clinical samples and as a bacterial symbiont of entomopathogenic nematodes of genus Heterohabditis. These protein toxins can be applied to, or genetically engineered into, insect larvae food and plants for insect control.
摘要翻译： 来自火炬属的蛋白质在接触时对昆虫有毒。 已经在哺乳动物临床样品中和作为异源真菌属的昆虫病原性线虫的细菌共生体中发现了Photorhabdus luminescens（以前的Xenorhabdus luminescens）。 这些蛋白质毒素可以应用于昆虫幼虫食品和植物进行昆虫控制或遗传工程化。
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