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    ULTRASOUND FOCUSING USING A CROSS-POINT SWITCH MATRIX
    4.
    发明申请
    ULTRASOUND FOCUSING USING A CROSS-POINT SWITCH MATRIX 审中-公开

    公开(公告)号：US20180360420A1

    公开(公告)日：2018-12-20

    申请号：US15627922

    申请日：2017-06-20

    申请人： Kobi VORTMAN ,  Shuki VITEK ,  Yoav LEVY

    发明人： Kobi VORTMAN ,  Shuki VITEK ,  Yoav LEVY

    IPC分类号： A61B8/00 ,  A61B5/01 ,  A61B5/055 ,  A61N7/02 ,  G01S7/52

    摘要： A system for delivering ultrasound energy to an internal anatomical target includes an ultrasound transducer having multiple transducer elements collectively operable as a phased array; multiple driver circuits, each being connected to at least one of the transducer elements; multiple phase circuits; a switch matrix selectably coupling the driver circuits to the phase circuits; and a controller configured for (i) receiving as input a target average intensity level and/or an energy level energy to be applied to the target and/or a temperature level in target, (ii) identifying multiple sets of the transducer elements, each of the sets corresponding to multiple transducer elements for shaping and/or focusing, as a phased array, ultrasound energy at the target across tissue intervening between the target and the ultrasound transducer, and (iii) sequentially operating the transducer-element sets to apply and maintain the target average energy level at the target. In various embodiments, the controller operates each of the transducer element sets in accordance with a pulse-width modulation pattern having a duty cycle selected to achieve the target average intensity level, energy level, and/or temperature level at the target in accordance with a time constant of the target tissue.

    ULTRASOUND FOCUSING IN DYNAMICALLY CHANGING MEDIA
    5.
    发明申请
    ULTRASOUND FOCUSING IN DYNAMICALLY CHANGING MEDIA 审中-公开

    公开(公告)号：US20190175954A1

    公开(公告)日：2019-06-13

    申请号：US15837365

    申请日：2017-12-11

    申请人： Yoav LEVY ,  Eyal ZADICARIO ,  Shuki VITEK ,  Javier GRINFELD ,  Ohad SILBIGER

    发明人： Yoav LEVY ,  Eyal ZADICARIO ,  Shuki VITEK ,  Javier GRINFELD ,  Ohad SILBIGER

    IPC分类号： A61N7/02

    摘要： Various approaches to generating and maintaining an ultrasound focus at a target region include configuring a controller to cause transmission of treatment ultrasound pulses from a transducer having multiple transducer elements; cause the transducer to transmit focusing ultrasound pulses to the target region and generate an acoustic reflector therein; measure reflections of the focusing ultrasound pulses from the acoustic reflector; based at least in part on the measured reflections, adjust a parameter value associated with one or more transducer elements so as to maintain and/or improve the ultrasound focus at the target region.

    MULTI-FREQUENCY ULTRASOUND TRANSDUCERS
    6.
    发明申请
    MULTI-FREQUENCY ULTRASOUND TRANSDUCERS 有权

    公开(公告)号：US20210077834A1

    公开(公告)日：2021-03-18

    申请号：US16959914

    申请日：2019-01-04

    申请人： Kobi VORTMAN ,  Shuki VITEK

    发明人： Kobi VORTMAN ,  Shuki VITEK

    IPC分类号： A61N7/00 ,  A61B5/055 ,  A61B5/107 ,  A61B5/00

    摘要： Treatment of target tissue in a target volume having multiple target regions includes causing an ultrasound transducer to transmit a first series of ultrasound waves having a first frequency to a first one of target regions; and causing the ultrasound transducer to transmit a second series of ultrasound waves having a second frequency, different from the first frequency, to a second one of the target regions, different from the first one of the target regions, based on one or more different anatomical characteristics (such as focal lengths) between the first and second ones of the target regions.

    ULTRASOUND-MEDIATED NEUROSTIMULATION
    7.
    发明申请
    ULTRASOUND-MEDIATED NEUROSTIMULATION 有权

    公开(公告)号：US20210170205A1

    公开(公告)日：2021-06-10

    申请号：US17267858

    申请日：2019-08-23

    申请人： Kobi VORTMAN ,  Shuki VITEK

    发明人： Kobi VORTMAN ,  Shuki VITEK

    IPC分类号： A61N7/02

    摘要： Various approaches to stimulating neural activity in one or more target regions associated with one or more brain diseases or disorders include transmitting the first sequence of ultrasound pulses to the target region(s); measuring a physiological parameter indicative of the neural activity at the target region(s) resulting from the ultrasound pulses; and based at least in part on the measurement, adjusting a parameter value associated with one or more transducer elements so as to achieve a target objective of the neural activity.

    FOCAL CAVITATION SIGNAL MEASUREMENT
    8.
    发明申请
    FOCAL CAVITATION SIGNAL MEASUREMENT 审中-公开

    公开(公告)号：US20190083065A1

    公开(公告)日：2019-03-21

    申请号：US15708214

    申请日：2017-09-19

    申请人： Shuki VITEK ,  Yoav LEVY

    发明人： Shuki VITEK ,  Yoav LEVY

    IPC分类号： A61B8/00 ,  A61B8/08

    摘要： Various approaches for detecting cavitation signals from a target region of a patient during a focused ultrasound procedure include an ultrasound transducer; an imaging device for acquiring physiological characteristics of multiple anatomical regions through which the cavitation signals from the target region travel; a controller configured to select one or more of the anatomical regions based at least in part on the physiological characteristics thereof and map the selected anatomical region(s) to one or more corresponding skin regions; and one or more cavitation detection devices attached to the corresponding skin region(s).