公开(公告)号：US20110100913A1

公开(公告)日：2011-05-05

申请号：US12915973

申请日：2010-10-29

申请人： Koichi MINAMI ,  Morihito IKEDA ,  Hiroshi ARAKATSU

发明人： Koichi MINAMI ,  Morihito IKEDA ,  Hiroshi ARAKATSU

IPC分类号： C02F1/44 ,  B01D61/00 ,  B01D11/04

CPC分类号： C02F1/44 ,  B01D61/00 ,  B01D61/002 ,  B01D61/145 ,  B01D61/243 ,  B01D61/364 ,  B01D61/422 ,  B01D61/58 ,  B01D2311/2626 ,  C02F1/444 ,  C02F1/445 ,  C02F1/4693 ,  C02F2301/08 ,  C02F2303/16

摘要： To provide a water purifier, containing: a diluting unit configured to bring targeted water for purification into contact with an aqueous solution containing a volatile solute and a polymer via a semi-permeable membrane so as to separate water from the targeted water by the semi-permeable membrane, and configured to dilute the aqueous solution with the separated water; a separating unit configured to separate the volatile solute and the polymer from the diluted aqueous solution obtained by the diluting unit so as to obtain purified water; and a dissolving unit configured to return the separated volatile solute by the separating unit to the aqueous solution containing the polymer, and to allow the separated volatile solute to dissolve in the aqueous solution containing the polymer.

摘要翻译： 本发明提供一种净水器，其特征在于，含有：稀释单元，其配置为使净化物与含有挥发性溶质的水溶液和聚合物通过半透膜接触，以通过半透过膜将水与目标水分离， 并且被配置为用分离的水稀释水溶液; 分离单元，被配置为从由稀释单元获得的稀释水溶液中分离挥发性溶质和聚合物以获得纯化水; 以及溶解单元，其被配置为将分离单元中分离的挥发性溶质返回到含有聚合物的水溶液中，并且使分离的挥发性溶质溶解在含有聚合物的水溶液中。

公开(公告)号：US20100317032A1

公开(公告)日：2010-12-16

申请号：US12796676

申请日：2010-06-09

申请人： Koichi MINAMI ,  Hirohiko TSUZUKI ,  Hiroshi UEDA ,  Masaki IHARA

发明人： Koichi MINAMI ,  Hirohiko TSUZUKI ,  Hiroshi UEDA ,  Masaki IHARA

IPC分类号： G01N33/53

CPC分类号： G01N33/5306

摘要： Provided is a method for detecting an antigen in a sample, the method including: bringing an unlabeled polypeptide and a labeled polypeptide into contact with an antigen in a sample, the unlabeled polypeptide being one of a pair including a VH-region polypeptide and a VL-region polypeptide which are separate and capable of cooperatively recognizing the antigen, and the labeled polypeptide being the other of the pair including the separate VH-region polypeptide and the VL-region polypeptide and being labeled with an environmentally-responsive substance at a site where the environmentally-responsive substance does not inhibit binding of the antigen, and detecting a change in the environmentally-responsive substance caused by a change in the environment around the labeled polypeptide after the contact. Also provided is an antibody fragment polypeptide set including the unlabeled polypeptide and the labeled polypeptide.

摘要翻译： 提供了一种用于检测样品中的抗原的方法，所述方法包括：使未标记的多肽和标记的多肽与样品中的抗原接触，所述未标记的多肽是包含VH区多肽和VL的一对之一 - 区域多肽，其是分离的并且能够协同识别抗原，并且标记的多肽是一对中的另一个，包括单独的VH区多肽和VL区多肽，并且在环境响应物质的标记位置处 环境响应物质不抑制抗原的结合，并且检测由接触后标记的多肽周围的环境变化引起的环境响应物质的变化。 还提供了包含未标记的多肽和标记的多肽的抗体片段多肽组。

公开(公告)号：US20100173326A1

公开(公告)日：2010-07-08

申请号：US12651689

申请日：2010-01-04

申请人： Koichi MINAMI

发明人： Koichi MINAMI

IPC分类号： G01N33/53 ,  B05D1/36 ,  B01J19/00

CPC分类号： G01N33/54373

摘要： A self assembling monolayer formed by the self assembling molecules is caused to bond onto the surface of a base material, and chelators are caused to bond onto the self assembling monolayer, to produce a substrate, in which the chelators are bound to the self assembling monolayer at a density within a range from 0.4/nm2 to 4/nm2. The bonding of the chelators onto the self assembling monolayer being performed within an organic solvent.

摘要翻译： 使由自组装分子形成的自组装单层结合到基材的表面上，并使螯合剂结合到自组装单层上以产生底物，其中螯合剂与自组装单层结合 在0.4 / nm 2至4 / nm 2的范围内的密度。 螯合剂在自组装单层上的键合在有机溶剂中进行。

公开(公告)号：US20090140209A1

公开(公告)日：2009-06-04

申请号：US12276004

申请日：2008-11-21

申请人： Koichi MINAMI ,  Hirohiko TSUZUKI

发明人： Koichi MINAMI ,  Hirohiko TSUZUKI

IPC分类号： C09K3/00

CPC分类号： C07K17/00 ,  G01N21/553

摘要： A complex, which has been formed by at least two pieces of a ligand and a first metal ion, is bound with a carrier. A second metal ion is then added onto the carrier, a new complex being thereby formed. A substance that contains a Group-15 or Group-16 atom, which has metal coordinating capability, is then fixed to the first metal ion and the second metal ion.

摘要翻译： 由至少两个配体和第一金属离子形成的络合物与载体结合。 然后将第二金属离子加入到载体上，从而形成新的络合物。 含有具有金属配位能力的第15族或第16族原子的物质然后固定在第一金属离子和第二金属离子上。

公开(公告)号：US20090016933A1

公开(公告)日：2009-01-15

申请号：US12171751

申请日：2008-07-11

申请人： Koichi MINAMI ,  Yohsuke Takeuchi

发明人： Koichi MINAMI ,  Yohsuke Takeuchi

IPC分类号： G01N21/01 ,  G01N33/543 ,  B01J19/00

CPC分类号： G01N33/54353 ,  C07K1/22 ,  C07K2319/21 ,  G01N33/54386 ,  G01N33/54393

摘要： A carrier comprises a base plate, a polymeric film, which has been bound on a surface of the base plate, and a ligand, which has been bound with the polymeric film. The ligand has been bound with the polymeric film at a density falling within the range of 1.0×1016 pieces/mm3 to 3.3×1018 pieces/mm3. The carrier is produced with a process, comprising the steps of: causing the polymeric film to bind on the base plate, and causing the ligand to bind with the polymeric film, the step of causing the ligand to bind with the polymeric film being performed in an organic solvent.

摘要翻译： 载体包括已经结合在基板的表面上的基板，聚合物膜和已经与聚合物膜结合的配体。 该配体以1.0×10 16个/ mm 3至3.3×10 18个/ mm 3的范围内的密度与聚合物膜结合。 通过一种方法制备载体，其包括以下步骤：使聚合物膜结合在基板上，并使配体与聚合物膜结合，使配体与聚合物膜结合的步骤在 有机溶剂。

公开(公告)号：US20090042745A1

公开(公告)日：2009-02-12

申请号：US12188508

申请日：2008-08-08

申请人： Koichi MINAMI ,  Yohsuke Takeuchi ,  Hirohiko Tsuzuki

发明人： Koichi MINAMI ,  Yohsuke Takeuchi ,  Hirohiko Tsuzuki

IPC分类号： C40B60/12

CPC分类号： G01N33/54353 ,  G01N33/54393 ,  G01N33/553 ,  G01N2610/00

摘要： A biosensor chip is constituted by: a substrate; a metal film which is physically attached to the substrate; and a self assembled monolayer constituted by alkyl chains, which is physically attached to the metal film. Ligands and at least one functional group, selected from a group consisting of a hydroxyl group, a carboxyl group, an alkoxy group, a methyl group, and hydrogen atoms are physically attached to the self assembled monolayer. The ratio between the total number of alkyl chains physically attached to the metal film and the number of alkyl chains which are covalently bonded with the ligands is within a range of 0.40 to 0.99.

摘要翻译： 生物传感器芯片由以下部分构成：基板; 物理地附接到基底的金属膜; 以及由金属膜物理附着的烷基链构成的自组装单层。 配体和选自羟基，羧基，烷氧基，甲基和氢原子的至少一个官能团物理连接到自组装单层。 与金属膜物理连接的烷基链的总数与与配体共价键合的烷基链的数量之间的比例在0.40至0.99的范围内。

公开(公告)号：US20090008861A1

公开(公告)日：2009-01-08

申请号：US12106633

申请日：2008-04-21

申请人： Yuki KASAHARA ,  Koichi MINAMI ,  Nobuhisa YAMAZAKI ,  Masaya TAKAMORI

发明人： Yuki KASAHARA ,  Koichi MINAMI ,  Nobuhisa YAMAZAKI ,  Masaya TAKAMORI

IPC分类号： B65H7/00

CPC分类号： B65H7/06 ,  B65H2511/52 ,  B65H2511/528 ,  B65H2513/20 ,  B65H2553/62 ,  B65H2557/23 ,  B65H2557/24 ,  B65H2801/06 ,  B65H2220/03 ,  B65H2220/01

摘要： A sheet feeding device includes a feeding unit that feeds a sheet; a rolling member that rolls by having contact with the sheet being fed by the feeding unit; a supporting member that moves along with a behavior of the sheet with supporting the rolling member so that the rolling member rolls in a feeding direction of the sheet at a predetermined position on the sheet; an acceleration measuring unit that measures accelerations acting on the supporting member in three directions; and a detecting unit that detects a feed error of the sheet based on the accelerations measured by the acceleration measuring unit.

摘要翻译： 片材进给装置包括供给单元，其供给片材; 滚动构件，其通过与由所述进给单元供给的所述薄片接触而滚动; 支撑构件，其与支撑滚动构件的片材的行为一起移动，使得滚动构件沿片材的预定位置沿片材的进给方向滚动; 加速度测量单元，其在三个方向上测量作用在所述支撑构件上的加速度; 以及检测单元，其基于由加速度测量单元测量的加速度来检测纸张的进给误差。