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公开(公告)号：US20100317762A1
公开(公告)日：2010-12-16
申请号：US12526070
申请日：2007-11-08
申请人： Koji Matsushige , Takeshi Suzuki , Shizuka Shimizu , Ayumi Dodomi
发明人： Koji Matsushige , Takeshi Suzuki , Shizuka Shimizu , Ayumi Dodomi
IPC分类号： A61K6/087
CPC分类号： A61K6/0023 , A61K6/0073 , C08L43/02
摘要： An adhesive composition for dental use exhibiting acidic property, including a mixture of a polymerizable monomer component (A) containing a phosphoric acid-type polymerizable monomer having an acidic group derived from phosphoric acid, and a multivalent metal ion-releasing component (B), wherein the multivalent metal ion-releasing component (B) is capable of releasing at least earth metal ions, and in the composition, earth metal ions stemming from the component (B) are present together with the phosphoric acid-type polymerizable monomer in such an amount that a total valency ratio (RE) defined by the following formula (1) is in a range of 0.2 to 3.0. The adhesive composition is capable of strongly adhering and fixing a composite resin or a prosthetic material to a tooth for extended periods of time maintaining stability. RE=TVE/TVA (1) wherein TVE is a total valency of the earth metal ions contained in said composition, and TVA is a total valency of the acidic groups of the phosphoric acid-type polymerizable monomer contained in said composition.
摘要翻译： 具有酸性的牙科用粘合剂组合物，包含含有磷酸酸性基团的磷酸型聚合性单体的聚合性单体成分（A）和多价金属离子释放成分（B）的混合物， 其中所述多价金属离子释放组分（B）能够至少释放地球金属离子，并且在组合物中，源自组分（B）的土金属离子与磷酸型可聚合单体一起存在于 由下式（1）定义的总化合价（RE）的范围在0.2〜3.0的范围内。 粘合剂组合物能够将复合树脂或修复材料牢固地粘附并固定在牙齿上，从而延长时间保持稳定性。 RE = TVE / TVA（1）其中TVE是所述组合物中所含的地球金属离子的总价，TVA是包含在所述组合物中的磷酸型可聚合单体的酸性基团的总价。
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公开(公告)号：US08513327B2
公开(公告)日：2013-08-20
申请号：US12526070
申请日：2007-11-08
申请人： Koji Matsushige , Takeshi Suzuki , Shizuka Shimizu , Ayumi Dodomi
发明人： Koji Matsushige , Takeshi Suzuki , Shizuka Shimizu , Ayumi Dodomi
CPC分类号： A61K6/0023 , A61K6/0073 , C08L43/02
摘要： An adhesive composition for dental use exhibiting acidic property, including a mixture of a polymerizable monomer component (A) containing a phosphoric acid-type polymerizable monomer having an acidic group derived from phosphoric acid, and a multivalent metal ion-releasing component (B), wherein the multivalent metal ion-releasing component (B) is capable of releasing at least earth metal ions, and in the composition, earth metal ions stemming from the component (B) are present together with the phosphoric acid-type polymerizable monomer in such an amount that a total valency ratio (RE) defined by the following formula (1) is in a range of 0.2 to 3.0. The adhesive composition is capable of strongly adhering and fixing a composite resin or a prosthetic material to a tooth for extended periods of time maintaining stability. RE=TVE/TVA (1) wherein TVE is a total valency of the earth metal ions contained in said composition, and TVA is a total valency of the acidic groups of the phosphoric acid-type polymerizable monomer contained in said composition.
摘要翻译： 具有酸性的牙科用粘合剂组合物，包含含有磷酸酸性基团的磷酸型聚合性单体的聚合性单体成分（A）和多价金属离子释放成分（B）的混合物， 其中所述多价金属离子释放组分（B）能够至少释放地球金属离子，并且在组合物中，源自组分（B）的土金属离子与磷酸型可聚合单体一起存在于 由下式（1）定义的总化合价（RE）的范围在0.2〜3.0的范围内。 粘合剂组合物能够将复合树脂或修复材料牢固地粘附并固定在牙齿上，从而延长时间保持稳定性。 RE = TVE / TVA（1）其中TVE是所述组合物中所含的地球金属离子的总价，TVA是包含在所述组合物中的磷酸型可聚合单体的酸性基团的总价。
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公开(公告)号：US20120006709A1
公开(公告)日：2012-01-12
申请号：US13236694
申请日：2011-09-20
CPC分类号： A61C5/66 , A61C2202/00 , A61C2202/01
摘要： A container which is not bulky at the time of shipping and can be stably stood on a suitable place. The container includes a lid member for closing a take-out opening (brittle portion) of the container body 2. On the lower outer side of the container body, there are formed slits for fitting the lid member to the container body after the container body and the lid member are separated apart, and auxiliary leg portions that protrude outward of the container body. The lid member is forming holding leg portions that protrude outward therefrom.Wing portions of the holding leg portions are inserted in the slits to fit the lid member to the container body, and the erected attitude of the container body is supported by the holding leg portions.
摘要翻译： 容器在运输时不笨重，可稳定地站在合适的地方。 容器包括用于封闭容器主体2的取出开口（脆性部分）的盖构件。在容器主体的下外侧形成有用于在容器主体之后将盖构件装配到容器主体的狭缝 并且盖构件被分开，并且辅助腿部突出到容器主体的外部。 盖构件形成从其向外突出的保持腿部。 保持腿部的翼部插入狭缝中以将盖构件装配到容器主体，并且容器主体的竖立姿态由保持腿部支撑。
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公开(公告)号：US08765837B2
公开(公告)日：2014-07-01
申请号：US12742524
申请日：2008-11-14
IPC分类号： A61K31/121 , C08J3/28
CPC分类号： A61K6/083 , A61K6/0073 , A61K6/0835 , C08F230/02 , C08L33/04 , C08L33/26 , C08F222/1006
摘要： [Problems] To provide a chemical polymerization type curable composition which can achieve a very large strength of adhesion even without irradiated with light, and is used in the field of dental therapy.[Means for Solution] A dental curable composition comprising (A) a polymerizable monomer component containing an acidic group-containing polymerizable monomer, (B) water, and (C) a chemical polymerization initiator component comprising a radical-generating species and a reactive species that generates radicals upon reacting with the radical-generating species; wherein, the dental curable composition is stored being divided into a plurality of packages, and is polymerized and cured by mixing together the components contained in the packages; and wherein one package (I) among the packages contains the component (A) and the component (B), and, further, contains polyvalent metal ions in an amount of 0.3 to 10 meq per gram of the polymerizable monomer component (A) contained in the package; and the chemical polymerization initiator (C) is stored being divided into at least two packages so that the radical-generating species and the reactive species do not come in contact with each other.
摘要翻译： [问题]提供一种化学聚合型固化性组合物，其即使不用光照射即可实现非常大的粘合强度，并且用于牙科治疗领域。 [解决方案]一种牙科用固化性组合物，其包含（A）含有含酸性基团的可聚合单体的可聚合单体组分，（B）水和（C）包含自由基产生物质和反应性物质的化学聚合引发剂组分 与自由基产生物质反应产生自由基; 其中，所述牙科用固化性组合物被分割成多个包装，通过将所述包装物中所含的成分混合在一起聚合固化; 并且其中所述包装中的一个包装（I）包含组分（A）和组分（B），并且还包含每克所述可聚合单体组分（A）含有0.3至10meq的量的多价金属离子 在包装中; 并且化学聚合引发剂（C）被储存为至少两个包装，使得自由基产生物质和反应性物质不彼此接触。
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公开(公告)号：US08104609B2
公开(公告)日：2012-01-31
申请号：US12073659
申请日：2008-03-07
CPC分类号： A61C5/66 , A61C2202/00 , A61C2202/01
摘要： A container which is not bulky at the time of shipping and can be stably stood on a suitable place. The container includes a lid member for closing a take-out opening (brittle portion) of the container body 2. On the lower outer side of the container body, there are formed slits for fitting the lid member to the container body after the container body and the lid member are separated apart, and auxiliary leg portions that protrude outward of the container body. The lid member is forming holding leg portions that protrude outward therefrom. Wing portions of the holding leg portions are inserted in the slits to fit the lid member to the container body, and the erected attitude of the container body is supported by the holding leg portions.
摘要翻译： 容器在运输时不笨重，可稳定地站在合适的地方。 容器包括用于封闭容器主体2的取出开口（脆性部分）的盖构件。在容器主体的下外侧形成有用于在容器主体之后将盖构件装配到容器主体的狭缝 并且盖构件被分开，并且辅助腿部突出到容器主体的外部。 盖构件形成从其向外突出的保持腿部。 保持腿部的翼部插入狭缝中以将盖构件装配到容器主体，并且容器主体的竖立姿态由保持腿部支撑。
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公开(公告)号：US20080217190A1
公开(公告)日：2008-09-11
申请号：US12073659
申请日：2008-03-07
CPC分类号： A61C5/66 , A61C2202/00 , A61C2202/01
摘要： A container which is not bulky at the time of shipping and can be stably stood on a suitable place. The container includes a lid member for closing a take-out opening (brittle portion) of the container body 2. On the lower outer side of the container body, there are formed slits for fitting the lid member to the container body after the container body and the lid member are separated apart, and auxiliary leg portions that protrude outward of the container body. The lid member is forming holding leg portions that protrude outward therefrom. Wing portions of the holding leg portions are inserted in the slits to fit the lid member to the container body, and the erected attitude of the container body is supported by the holding leg portions.
摘要翻译： 容器在运输时不笨重，可稳定地站在合适的地方。 容器包括用于封闭容器主体2的取出开口（脆性部分）的盖构件。在容器主体的下外侧形成有用于在容器主体之后将盖构件装配到容器主体的狭缝 并且盖构件被分开，并且辅助腿部突出到容器主体的外部。 盖构件形成从其向外突出的保持腿部。 保持腿部的翼部插入狭缝中以将盖构件装配到容器主体，并且容器主体的竖立姿态由保持腿部支撑。
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公开(公告)号：US20120238658A1
公开(公告)日：2012-09-20
申请号：US13511952
申请日：2010-12-02
申请人： Koji Matsushige , Qian Cui , Ayumi Dodomi
发明人： Koji Matsushige , Qian Cui , Ayumi Dodomi
IPC分类号： A61K6/00
CPC分类号： A61K6/0023 , C08L33/10
摘要： [Problems] To provide a liquid dental adhesive composition which contains a phosphoric acid-type compound having a hydrogenphosphoric diester group as an acidic group-containing polymerizable monomer and, further, contains polyvalent metal ions, effectively preventing not only the gelation but also the formation of precipitates (cloudiness) during the storage.[Means for Solution] A dental adhesive composition which is acidic and contains an acidic group-containing polymerizable monomer (A), polyvalent metal ions (B), water (C), a water-soluble organic solvent (D) and fluoride ions (E), wherein at least 35% by mole of the acidic group-containing polymerizable monomer (A) is a phosphoric acid-type compound having a hydrogenphosphoric diester group, and the contents of the fluoride ions (E) and the polyvalent metal ions (B) are so set that a valence number ratio (RF) defined by the following formula (1): RF=VF/TVP (1) wherein VF is a valence number of the fluoride ions (E) contained in the composition, and TVP is a total valence number of the polyvalent metal ions (B) contained in the composition, satisfies a range of 0.2 to 2.0.
摘要翻译： [问题]提供一种液态牙科用粘合剂组合物，其含有具有磷酸二酯基的磷酸型化合物作为含酸性基团的可聚合单体，并且还含有多价金属离子，不仅有效地防止凝胶化，而且有效地防止形成 的沉淀物（云量）。 [解决方案]一种酸性并含有含酸性基团的可聚合单体（A），多价金属离子（B），水（C），水溶性有机溶剂（D）和氟离子（D）的牙科粘合剂组合物 E），其中，含酸性基团的可聚合单体（A）的至少35摩尔％为具有氢磷酸二酯基团的磷酸型化合物，并且氟离子（E）和多价金属离子（E） B）被定义为由以下公式（1）定义的价数比（RF）：RF = VF / TVP（1）其中VF是组合物中包含的氟离子（E）的价数，TVP 是组合物中所含的多价金属离子（B）的总价数，满足0.2〜2.0的范围。
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公开(公告)号：US20100261144A1
公开(公告)日：2010-10-14
申请号：US12742524
申请日：2008-11-14
CPC分类号： A61K6/083 , A61K6/0073 , A61K6/0835 , C08F230/02 , C08L33/04 , C08L33/26 , C08F222/1006
摘要： [Problems] To provide a chemical polymerization type curable composition which can achieve a very large strength of adhesion even without irradiated with light, and is used in the field of dental therapy.[Means for Solution] A dental curable composition comprising (A) a polymerizable monomer component containing an acidic group-containing polymerizable monomer, (B) water, and (C) a chemical polymerization initiator component comprising a radical-generating species and a reactive species that generates radicals upon reacting with the radical-generating species; wherein, the dental curable composition is stored being divided into a plurality of packages, and is polymerized and cured by mixing together the components contained in the packages; and wherein one package (I) among the packages contains the component (A) and the component (B), and, further, contains polyvalent metal ions in an amount of 0.3 to 10 meq per gram of the polymerizable monomer component (A) contained in the package; and the chemical polymerization initiator (C) is stored being divided into at least two packages so that the radical-generating species and the reactive species do not come in contact with each other.
摘要翻译： [问题]提供一种化学聚合型固化性组合物，其即使不用光照射即可实现非常大的粘合强度，并且用于牙科治疗领域。 [解决方案]一种牙科用固化性组合物，其包含（A）含有含酸性基团的可聚合单体的可聚合单体组分，（B）水和（C）包含自由基产生物质和反应性物质的化学聚合引发剂组分 与自由基产生物质反应产生自由基; 其中，所述牙科用固化性组合物被分割成多个包装，通过将所述包装物中所含的成分混合在一起聚合固化; 并且其中所述包装中的一个包装（I）包含组分（A）和组分（B），并且还包含每克所述可聚合单体组分（A）含有0.3至10meq的量的多价金属离子 在包装中; 并且化学聚合引发剂（C）被储存为至少两个包装，使得自由基产生物质和反应性物质不彼此接触。
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公开(公告)号：US08815974B2
公开(公告)日：2014-08-26
申请号：US13511952
申请日：2010-12-02
申请人： Koji Matsushige , Qian Cui , Ayumi Dodomi
发明人： Koji Matsushige , Qian Cui , Ayumi Dodomi
CPC分类号： A61K6/0023 , C08L33/10
摘要： [Problems] To provide a liquid dental adhesive composition which contains a phosphoric acid-type compound having a hydrogenphosphoric diester group as an acidic group-containing polymerizable monomer and, further, contains polyvalent metal ions, effectively preventing not only the gelation but also the formation of precipitates (cloudiness) during the storage.[Means for Solution] A dental adhesive composition which is acidic and contains an acidic group-containing polymerizable monomer (A), polyvalent metal ions (B), water (C), a water-soluble organic solvent (D) and fluoride ions (E), wherein at least 35% by mole of the acidic group-containing polymerizable monomer (A) is a phosphoric acid-type compound having a hydrogenphosphoric diester group, and the contents of the fluoride ions (E) and the polyvalent metal ions (B) are so set that a valence number ratio (RF) defined by the following formula (1): RF=VF/TVP (1) wherein VF is a valence number of the fluoride ions (E) contained in the composition, and TVP is a total valence number of the polyvalent metal ions (B) contained in the composition, satisfies a range of 0.2 to 2.0.
摘要翻译： [问题]提供一种液态牙科用粘合剂组合物，其含有具有磷酸二酯基的磷酸型化合物作为含酸性基团的可聚合单体，并且还含有多价金属离子，不仅有效地防止凝胶化，而且有效地防止形成 的沉淀物（云量）。 [解决方案]一种酸性并含有含酸性基团的可聚合单体（A），多价金属离子（B），水（C），水溶性有机溶剂（D）和氟离子（D）的牙科粘合剂组合物 E），其中，含酸性基团的可聚合单体（A）的至少35摩尔％为具有氢磷酸二酯基团的磷酸型化合物，并且氟离子（E）和多价金属离子（E） B）被定义为由以下公式（1）定义的价数比（RF）：RF = VF / TVP（1）其中VF是组合物中包含的氟离子（E）的价数，TVP 是组合物中所含的多价金属离子（B）的总价数，满足0.2〜2.0的范围。
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公开(公告)号：USD588906S1
公开(公告)日：2009-03-24
申请号：US29287669
申请日：2007-09-06
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