公开(公告)号：US10647685B2

公开(公告)日：2020-05-12

申请号：US16015596

申请日：2018-06-22

Applicant: Korea Institute of Science and Technology

Inventor： Eun Joo Roh ,  Karam Mohamed Hasan Fara Ahmed ,  So Ra Paik ,  Woo Young Hur ,  Elkamhawy Ahmed

IPC: C07D239/48 ,  A61P1/00 ,  A61P19/02 ,  C07D413/12

Abstract: The present invention relates to a 6-phenoxypyrimidine derivative, a method for preparing the compound and a pharmaceutical composition containing the compound as an active ingredient. Because the 6-phenoxypyrimidine compound represented by Chemical Formula 1 according to the present invention has an activity of inhibiting the production of nitric oxide (NO) as an inflammation-related factor, it is useful in treating and preventing inflammatory diseases including immunological diseases.