公开(公告)号：US20220177851A1

公开(公告)日：2022-06-09

申请号：US17602170

申请日：2020-04-09

Applicant: Korea University Research and Business Foundation

Inventor： Seung Kwon YOU ,  In Yong KIM ,  Wei Wei GAO ,  Phil Jun KANG ,  Won-Jin YUN ,  Gyuman PARK

IPC: C12N5/071 ,  C12N15/86 ,  A61K35/22 ,  C07K14/47

Abstract: Disclosed is a method for inducing direct reprogramming of urine cells into renal progenitor cells and a pharmaceutical composition including the renal progenitor cells reprogrammed by the method for preventing or treating renal cell injury disease. The method can make the mass production of customized reprogrammed renal progenitor cells by using urine cells, which are somatic cells easily and repeatedly obtainable without inconvenience and pain and as such, can be applied to incurable disease fields expandable to the renal injury therapy and kidney regeneration fields and to the production of cell therapy products.