公开(公告)号：US4626500A

公开(公告)日：1986-12-02

申请号：US776177

申请日：1985-09-13

申请人： Kozo Sato ,  Hiroshi Kitaguchi ,  Hiroyuki Hirai

发明人： Kozo Sato ,  Hiroshi Kitaguchi ,  Hiroyuki Hirai

IPC分类号： G03C7/00 ,  G03C1/498 ,  G03C8/40 ,  G03C1/06 ,  G03C1/40 ,  G03C5/54

CPC分类号： G03C1/49845 ,  Y10S430/156

摘要： A heat-developable photographic light-sensitive material is described, comprising a support having thereon, at least one layer containing a compound represented by the general formula (I) or (II) below: ##STR1## wherein R and R' each represents a group selected from a hydrogen atom, an alkyl group, a cycloalkyl group, an alkenyl group, an alkynyl group, an aralkyl group, an aryl group, an amino group, an acylamino group, an alkoxy group, an alkylthio group, a sulfonylamino group, a heterocyclic ring group and a substituted group of them; X represents atoms forming a 5-membered or 6-membered ring; A represents a group causing a decarboxylation reaction.This heat-developable photographic light-sensitive material provides a high maximum density and low fog by heat-developing at a relatively low temperature and for a short time.

摘要翻译： 描述了一种可热显影的照相感光材料，其包括其上具有载体的至少一层，其含有由下列通式（I）或（II）表示的化合物：图像（I）图像（II） ）其中R和R'各自表示选自氢原子，烷基，环烷基，烯基，炔基，芳烷基，芳基，氨基，酰氨基，烷氧基 基团，烷硫基，磺酰氨基，杂环基和它们的取代基; X表示形成5元或6元环的原子; A表示引起脱羧反应的基团。 该热显影照相感光材料通过在相对较低的温度和短时间内的热显影提供高的最大密度和低的雾度。

公开(公告)号：US4675277A

公开(公告)日：1987-06-23

申请号：US780132

申请日：1985-09-25

申请人： Kozo Sato ,  Hiroshi Kitaguchi ,  Hiroyuki Hirai

发明人： Kozo Sato ,  Hiroshi Kitaguchi ,  Hiroyuki Hirai

IPC分类号： G03C8/40 ,  G03C1/34 ,  G03C1/498 ,  G03C7/00 ,  G03C1/06

CPC分类号： G03C1/49845 ,  Y10S430/156

摘要： A heat developable light-sensitive material comprising a support having provided thereon at least a light-sensitive silver halide, a binder, and a compound capable of ring-closure to produce a benzimidazole ring upon heat development can be developed to an increased maximum density with less fogging at a relatively low temperature in a short period of time.

摘要翻译： 包含其上提供有至少一种感光卤化银，粘合剂和能够闭合以在热显影时产生苯并咪唑环的化合物的支持体的可热显影的感光材料可以发展成具有增加的最大密度， 在较短的时间内在相对较低的温度下减少雾化。

公开(公告)号：US4729936A

公开(公告)日：1988-03-08

申请号：US867176

申请日：1986-05-27

申请人： Hiroshi Kitaguchi ,  Kozo Sato ,  Masatoshi Kato

发明人： Hiroshi Kitaguchi ,  Kozo Sato ,  Masatoshi Kato

IPC分类号： G03C7/00 ,  C07D231/12 ,  G03C7/305 ,  G03C8/40 ,  G03C8/54 ,  G03C5/26 ,  G03C1/00 ,  G03C5/34 ,  G03C5/54

CPC分类号： C07D231/12 ,  G03C7/30511 ,  G03C8/408 ,  Y10S430/156 ,  Y10S430/158 ,  Y10S430/16 ,  Y10S430/161

摘要： An image forming process including a heating step is disclosed. The process comprises conducting said heating step in the presence of at least one compound represented by formula (I), (II), or (III). ##STR1## wherein R.sup.1 represents ##STR2## wherein R.sup.11 and R.sup.12 each represents a substituted or unsubstituted alkyl group, a substituted or unsubstituted cycloalkyl group, a substituted or unsubstituted alkenyl group, a substituted or unsubstituted aralkyl group, a substituted or unsubstituted aryl group, a substituted or unsubstituted heterocyclic group, a substituted or unsubstituted alkyloxy group, a substituted or unsubstituted aryloxy group, a substituted or unsubstituted alkylthio group, a substituted or unsubstituted arylthio group or a substituted or unsubstituted amino group; R.sup.11 and R.sup.12 together form a 5-membered or 6-membered ring; Q represents a hydrogen atom or a substituted or unsubstituted alkyl group, a substituted or unsubstituted cycloalkyl group, or a substituted or unsubstituted aryl group, or Q represents a group linked to the pyrazole ring, TIME or PUG either directly or through another atom to form a ring; TIME represents a timing group; PUG represents a photographically useful group; and n represents 0 or a positive integer.The image forming process provides for little variation in photographic characteristics even when there is a substantial variation in the heat-processing temperature.

摘要翻译： 公开了一种包括加热步骤的图像形成过程。 该方法包括在至少一种由式（I），（II）或（III）表示的化合物的存在下进行所述加热步骤。 （Ⅰ）其中R1表示其中R11和R12各自表示取代或未取代的烷基，取代或未取代的环烷基，取代或未取代的烯基 取代或未取代的芳烷基，取代或未取代的芳基，取代或未取代的杂环基，取代或未取代的烷氧基，取代或未取代的芳氧基，取代或未取代的烷硫基，取代或未取代的芳硫基， 取代或未取代的氨基; R11和R12一起形成5元或6元环; Q表示氢原子或取代或未取代的烷基，取代或未取代的环烷基或取代或未取代的芳基，或Q表示与吡唑环连接的基团，TIME或PUG直接或通过另一个原子形成 戒指; TIME代表一个时间组; PUG代表一个摄影有用的组; n表示0或正整数。 即使在热处理温度存在显着变化的情况下，图像形成处理也提供了摄影特性的很小变化。

公开(公告)号：US4473632A

公开(公告)日：1984-09-25

申请号：US566450

申请日：1983-12-28

申请人： Hiroshi Kitaguchi ,  Kozo Sato ,  Shinsaku Fujita ,  Hideki Naito

发明人： Hiroshi Kitaguchi ,  Kozo Sato ,  Shinsaku Fujita ,  Hideki Naito

IPC分类号： C09B29/01 ,  G03C1/06 ,  G03C1/498 ,  G03C8/40 ,  G03C5/54 ,  G03C1/10 ,  G03C7/00

CPC分类号： C09B29/0003 ,  G03C1/06 ,  G03C1/49854 ,  G03C8/4033

摘要： A heat-developable color photographic material is disclosed. The material is comprised of a support having thereon a light-sensitive silver halide, a hydrophilic binder and a dye releasing redox compound represented by the general formula (I): ##STR1## the substituents within the general formula (I) are disclosed within the specification. The heat-developable color photographic material can easily provide a clear and stable color image by imagewise exposure to light and a heat-development procedure. A method of forming a color image using the heat-developable color photographic material is also disclosed.

摘要翻译： 公开了一种可热显影的彩色照相材料。 该材料由其上具有感光卤化银，亲水性粘合剂和由通式（I）表示的染料释放氧化还原化合物的载体组成：通式（I）中的取代基是 在说明书内公开。 热显影彩色照相材料可以通过成像曝光和热显影方法容易地提供清晰和稳定的彩色图像。 还公开了使用可热显色彩色照相材料形成彩色图像的方法。

公开(公告)号：US08193224B2

公开(公告)日：2012-06-05

申请号：US11576429

申请日：2005-09-30

申请人： Masataka Ihara ,  Kiyosei Takasu ,  Khanitha Pudhom ,  Hiroshi Kitaguchi ,  Masayuki Kawakami ,  Kozo Sato

发明人： Masataka Ihara ,  Kiyosei Takasu ,  Khanitha Pudhom ,  Hiroshi Kitaguchi ,  Masayuki Kawakami ,  Kozo Sato

IPC分类号： A61K31/427 ,  A61K31/428 ,  C07D277/66 ,  C07D277/04 ,  C07D277/84

CPC分类号： C07D277/84 ,  A61K31/427 ,  A61K31/428 ,  A61K31/4439 ,  A61K31/4709 ,  C07D277/64 ,  C07D417/14 ,  Y02A50/409 ,  Y02A50/411 ,  Y02A50/414

摘要： The present invention is to provide a medicinal composition for preventing or treating parasitic protozoan infections, having a high selective toxicity against parasitic protozoan infection, and a superior preventive or treating effect. A medicinal composition for preventing or treating parasitic protozoan infections comprises a compound shown by the following general formula (1) as an active ingredient (wherein R represents an alkyl group, aryl group or heterocyclic group; A and B each independently represents a 5- or 6-membered ring containing at least one hetero atom, or a condensation ring wherein 1 or more 3- to 8-membered ring is condensed thereto; Y represents S, O, Se, or —NR1— (R1 represents an alkyl group, aryl group or heterocyclic group); L1, L2, L3, L4 and L5 each independently represents a methine group; Q represents a physiologically acceptable anion; k represents an integer of 0 to 2, necessary to make the electric charge of the whole molecule 0; p and q each represents an integer of 0 to 3, wherein the sum of p and q is 1 or more, and 6 or less).

摘要翻译： 本发明提供一种用于预防或治疗对寄生原虫感染具有高选择性毒性的寄生原虫感染的药物组合物，以及优异的预防或治疗效果。 用于预防或治疗寄生原生动物感染的药物组合物包含由以下通式（1）表示的化合物作为活性成分（其中R表示烷基，芳基或杂环基; A和B各自独立地表示5-或 含有至少一个杂原子的6元环或其中1个以上3〜8元环稠合的缩合环; Y表示S，O，Se或-NR1-（R1表示烷基，芳基 基团或杂环基）; L1，L2，L3，L4和L5各自独立地表示次甲基; Q表示生理上可接受的阴离子; k表示使整个分子0的电荷所必需的0至2的整数; p和q各自表示0〜3的整数，p和q的和为1以上且6以下）。

公开(公告)号：US07795285B2

公开(公告)日：2010-09-14

申请号：US11576426

申请日：2005-09-29

申请人： Masataka Ihara ,  Kiyosei Takasu ,  Khanitha Pudhom ,  Hiroshi Kitaguchi ,  Masayuki Kawakami ,  Kozo Sato

发明人： Masataka Ihara ,  Kiyosei Takasu ,  Khanitha Pudhom ,  Hiroshi Kitaguchi ,  Masayuki Kawakami ,  Kozo Sato

IPC分类号： A01N43/78

CPC分类号： C07D417/14 ,  A61K31/428 ,  A61K31/4439 ,  A61K31/4709 ,  Y02A50/414

摘要： The present invention is to provide an anti-trypanosomiasis agent having a high selective toxicity, and high preventing or treating effect against trypanosomiasis, comprising a compound shown by the following general formula (1) as an active ingredient (wherein R1 and R2 each independently represents a hydrogen atom, halogen atom, hydroxyl group, oxygen atom, C1-5 alkyl group, C1-5 alkoxy group, C5-8 aryl group, C5-8 aryloxy group, C2-6 alkoxycarbonyl group or C2-6 alkylaminocarbonyl group, and may be bound to each other; R3, R4, and R5 each independently represents a C1-5 alkyl group or C5-8 aryl group; R6 and R7 each independently represents a hydrogen atom, halogen atom, hydroxyl group, oxygen atom, C1-8 alkyl group, C1-5 alkoxy group, C5-8 aryl group, C5-8 aryloxy group, or C2-6 alkoxycarbonyl group, and may be bound to each other; Y and Z each independently represents an atom group necessary to form a 5- or 6-membered heterocycle; m and n each represent 0 or 1; Q represents a physiologically acceptable anion; k represents an integer of 0 to 2, necessary to make the electric charge of the whole molecule 0).

摘要翻译： 本发明提供具有高选择性毒性和对锥虫病的高预防或治疗作用的抗锥虫病药，其包含由以下通式（1）表示的化合物作为活性成分（其中R 1和R 2各自独立地表示 氢原子，卤素原子，羟基，氧原子，C 1-5烷基，C 1-5烷氧基，C 5-8芳基，C 5-8芳氧基，C 2-6烷氧基羰基或C 2-6烷基氨基羰基， 可以相互结合; R3，R4和R5各自独立地表示C1-5烷基或C5-8芳基; R6和R7各自独立地表示氢原子，卤素原子，羟基，氧原子，C1- 8个烷基，C 1-5烷氧基，C 5-8芳基，C 5-8芳氧基或C 2-6烷氧基羰基，并且可以彼此结合; Y和Z各自独立地表示形成 5-或6-元杂环; m和n各自表示0或1; Q表示物理 生理上可接受的阴离子 k表示0〜2的整数，使整个分子的电荷为0）。

公开(公告)号：US20100113789A1

公开(公告)日：2010-05-06

申请号：US11576429

申请日：2005-09-30

申请人： Masataka Ihara ,  Kiyosei Takasu ,  Khanitha Pudhom ,  Hiroshi Kitaguchi ,  Masayuki Kawakami ,  Kozo Sato

发明人： Masataka Ihara ,  Kiyosei Takasu ,  Khanitha Pudhom ,  Hiroshi Kitaguchi ,  Masayuki Kawakami ,  Kozo Sato

IPC分类号： C07D417/14

CPC分类号： C07D277/84 ,  A61K31/427 ,  A61K31/428 ,  A61K31/4439 ,  A61K31/4709 ,  C07D277/64 ,  C07D417/14 ,  Y02A50/409 ,  Y02A50/411 ,  Y02A50/414

摘要： The present invention is to provide a medicinal composition for preventing or treating parasitic protozoan infections, having a high selective toxicity against parasitic protozoan infection, and a superior preventive or treating effect. A medicinal composition for preventing or treating parasitic protozoan infections comprises a compound shown by the following general formula (1) as an active ingredient (wherein R represents an alkyl group, aryl group or heterocyclic group; A and B each independently represents a 5- or 6-membered ring containing at least one hetero atom, or a condensation ring wherein 1 or more 3- to 8-membered ring is condensed thereto; Y represents S, O, Se, or —NR1— (R1 represents an alkyl group, aryl group or heterocyclic group); L1, L2, L3, L4 and L5 each independently represents a methine group; Q represents a physiologically acceptable anion; k represents an integer of 0 to 2, necessary to make the electric charge of the whole molecule 0; p and q each represents an integer of 0 to 3, wherein the sum of p and q is 1 or more, and 6 or less.)

摘要翻译： 本发明提供一种用于预防或治疗对寄生原虫感染具有高选择性毒性的寄生原虫感染的药物组合物，以及优异的预防或治疗效果。 用于预防或治疗寄生原生动物感染的药物组合物包含由以下通式（1）表示的化合物作为活性成分（其中R表示烷基，芳基或杂环基; A和B各自独立地表示5-或 含有至少一个杂原子的6元环或其中1个以上3〜8元环稠合的缩合环; Y表示S，O，Se或-NR1-（R1表示烷基，芳基 基团或杂环基）; L1，L2，L3，L4和L5各自独立地表示次甲基; Q表示生理上可接受的阴离子; k表示使整个分子0的电荷所必需的0至2的整数; p和q各自表示0〜3的整数，p和q的和为1以上6以下）

公开(公告)号：US4824759A

公开(公告)日：1989-04-25

申请号：US827139

申请日：1986-02-07

申请人： Kozo Sato ,  Hiroshi Kitaguchi ,  Masashi Takeuchi ,  Masaaki Tsukase ,  Masatoshi Kato

发明人： Kozo Sato ,  Hiroshi Kitaguchi ,  Masashi Takeuchi ,  Masaaki Tsukase ,  Masatoshi Kato

IPC分类号： G03C7/00 ,  G03C1/498 ,  G03C1/61 ,  G03C8/40 ,  G03C1/06 ,  G03C

CPC分类号： G03C1/49845 ,  G03C1/61 ,  Y10S430/156 ,  Y10S430/158 ,  Y10S430/161

摘要： A method for forming an image, which comprises heating a light-sensitive material in the presence of a compound capable of forming a 2-mercaptobenzazole ring by a ring closing reaction when heated.In accordance with the method of the present invention, development is stopped at an appropriate time of development whereby an image having a high maximum density and low fog is obtained.A heat-developable light-sensitive material containing the compound is also disclosed.

摘要翻译： 一种形成图像的方法，其包括在加热时通过闭环反应在能够形成2-巯基吲唑环的化合物的存在下加热感光材料。 根据本发明的方法，在合适的显影时间停止显影，从而获得具有高的最大浓度和低雾度的图像。 还公开了含有该化合物的可热显影的感光材料。

公开(公告)号：US4678735A

公开(公告)日：1987-07-07

申请号：US774427

申请日：1985-09-10

申请人： Hiroshi Kitaguchi ,  Masatoshi Kato ,  Kozo Sato ,  Masasi Takeuchi ,  Masaaki Tsukase

发明人： Hiroshi Kitaguchi ,  Masatoshi Kato ,  Kozo Sato ,  Masasi Takeuchi ,  Masaaki Tsukase

IPC分类号： G03C7/305 ,  G03C8/40 ,  G03C5/54 ,  G03C1/34

CPC分类号： G03C8/408 ,  G03C7/30511 ,  Y10S430/158 ,  Y10S430/161

摘要： A heat developable light-sensitive material containing a compound represented by general formula (I) described below in a light-sensitive layer or an image receiving layer thereof: ##STR1## wherein X represents an atomic group necessary to complete a benzene ring or a naphthalene ring; R represents a group convertible to a hydroxy group or a dissociation form thereof at the time of heat development; Y represents an atomic group necessary to complete a 5-membered or 6-membered heterocyclic group containing at least one nitrogen atom; Q represents a hydrogen atom, an alkyl group, a substituted alkyl group, an aryl group, or a substituted aryl group; TIME represents a timing group; and n represents 0 or a positive integer. The heat developable light-sensitive material containing the compound represented by general formula (I), which is stable at room temperature and releases a development inhibitor to stop the development at the time of heat development, can provide a color image having a high S/N ratio and a high density.

摘要翻译： 含有下述通式（I）表示的化合物的感光层或图像接收层的热显影性感光材料：其中X表示完成苯环所需的原子团 或萘环; R表示在热显影时可转化为羟基或其解离形式的基团; Y表示完成含有至少一个氮原子的5元或6元杂环基必需的原子团; Q表示氢原子，烷基，取代的烷基，芳基或取代的芳基; TIME代表一个时间组; n表示0或正整数。 含有由通式（I）表示的化合物在室温下稳定并释放显影抑制剂以在显影时停止显影的热显影光敏材料可以提供具有高S / N比和高密度。

公开(公告)号：US20080045574A1

公开(公告)日：2008-02-21

申请号：US11576426

申请日：2005-09-29

申请人： Masataka Ihara ,  Kiyosei Takasu ,  Khanitha Pudhom ,  Hiroshi Kitaguchi ,  Masayuki Kawakami ,  Kozo Sato

发明人： Masataka Ihara ,  Kiyosei Takasu ,  Khanitha Pudhom ,  Hiroshi Kitaguchi ,  Masayuki Kawakami ,  Kozo Sato

IPC分类号： A61K31/426 ,  A61P33/00

CPC分类号： C07D417/14 ,  A61K31/428 ,  A61K31/4439 ,  A61K31/4709 ,  Y02A50/414

摘要： The present invention is to provide an anti-trypanosomiasis agent having a high selective toxicity, and high preventing or treating effect against trypanosomiasis, comprising a compound shown by the following general formula (1) as an active ingredient (wherein R1 and R2 each independently represents a hydrogen atom, halogen atom, hydroxyl group, oxygen atom, C1-5 alkyl group, C1-5 alkoxy group, C5-8 aryl group, C5-8 aryloxy group, C2-6 alkoxycarbonyl group or C2-6 alkylaminocarbonyl group, and may be bound to each other; R3, R4, and R5 each independently represents a C1-5 alkyl group or C5-8 aryl group; R6 and R7 each independently represents a hydrogen atom, halogen atom, hydroxyl group, oxygen atom, C1-8 alkyl group, C1-5 alkoxy group, C5-8 aryl group, C5-8 aryloxy group, or C2-6 alkoxycarbonyl group, and may be bound to each other; Y and Z each independently represents an atom group necessary to form a 5- or 6-membered heterocycle; m and n each represent 0 or 1; Q represents a physiologically acceptable anion; k represents an integer of 0 to 2, necessary to make the electric charge of the whole molecule 0).

摘要翻译： 本发明提供具有高选择性毒性和对锥虫病的高预防或治疗作用的抗锥虫病药，其包含由以下通式（1）表示的化合物作为活性成分（其中R 1， / O 2和R 2各自独立地表示氢原子，卤素原子，羟基，氧原子，C 1-5烷基，C 1-5 C 5〜8芳基，C 5〜8芳氧基，C 2-6烷氧基羰基或C 2-6个亚烷基氨基羰基，并且可以彼此结合; R 3，R 4和R 5 >各自独立地表示C 1-5烷基或C 5-8芳基; R 6和R 7， SUP各自独立地表示氢原子，卤素原子，羟基，氧原子，C 1-8烷基，C 1-5烷氧基，C 1〜 5-8芳基，C 5-8芳氧基，或C 1〜 并且可以相互结合; Y和Z各自独立地表示形成5-或6-元杂环所必需的原子团; m和n各自表示0或1; Q表示生理上可接受的阴离子; k表示0〜2的整数，使整个分子的电荷为0）。