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公开(公告)号:US08394769B2
公开(公告)日:2013-03-12
申请号:US12671953
申请日:2008-08-07
摘要: The present invention provides an anti-hypertensive agent. The anti-hypertensive agent of the present invention contains, as an active ingredient, at least one peptide selected from the group consisting of peptides originally derived from globin proteolysate, each of which consists of one of the following amino acid sequences (1) to (6), or a globin proteolysate containing at least one of the peptides: (1) Val-Val-Tyr-Pro (SEQ ID: NO. 1); (2) Trp-Gly-Lys-Val-Asn (SEQ ID: NO. 2); (3) Trp-Gly-Lys-Val (SEQ ID: NO. 3); (4) Trp-Gly-Lys (SEQ ID: NO. 4); (5) Ala-Ala-Trp-Gly-Lys (SEQ ID: NO. 5); and (6) Phe-Glu-Ser (SEQ ID: NO. 6).
摘要翻译: 本发明提供抗高血压药。 作为活性成分,本发明的抗高血压剂含有选自由蛋白水解蛋白多糖最初来源的肽组成的组中的至少一种,其中的肽由以下氨基酸序列(1)〜( 6)或含有至少一种肽的球蛋白蛋白水解物:(1)Val-Val-Tyr-Pro(SEQ ID NO:1); (2)Trp-Gly-Lys-Val-Asn(SEQ ID NO:2); (3)Trp-Gly-Lys-Val(SEQ ID NO:3); (4)Trp-Gly-Lys(SEQ ID NO:4); (5)Ala-Ala-Trp-Gly-Lys(SEQ ID NO:5); 和(6)Phe-Glu-Ser(SEQ ID NO:6)。
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公开(公告)号:US20110166073A1
公开(公告)日:2011-07-07
申请号:US12671953
申请日:2008-08-07
IPC分类号: A61K38/06 , C07K5/097 , C07K5/087 , C07K5/103 , C07K5/117 , C07K7/06 , A61K38/07 , A61K38/08 , A61P9/12
摘要: The present invention provides an anti-hypertensive agent. The anti-hypertensive agent of the present invention contains, as an active ingredient, at least one peptide selected from the group consisting of peptides originally derived from globin proteolysate, each of which consists of one of the following amino acid sequences (1) to (6), or a globin proteolysate containing at least one of the peptides: (1) Val-Val-Tyr-Pro (SEQ ID: NO. 1); (2) Trp-Gly-Lys-Val-Asn (SEQ ID: NO. 2); (3) Trp-Gly-Lys-Val (SEQ ID: NO. 3); (4) Trp-Gly-Lys (SEQ ID: NO. 4); (5) Ala-Ala-Trp-Gly-Lys (SEQ ID: NO. 5); and (6) Phe-Glu-Ser (SEQ ID: NO. 6).
摘要翻译: 本发明提供抗高血压药。 作为活性成分,本发明的抗高血压剂含有选自由蛋白水解蛋白多糖最初来源的肽组成的组中的至少一种,其中的肽由以下氨基酸序列(1)〜( 6)或含有至少一种肽的球蛋白蛋白水解物:(1)Val-Val-Tyr-Pro(SEQ ID NO:1); (2)Trp-Gly-Lys-Val-Asn(SEQ ID NO:2); (3)Trp-Gly-Lys-Val(SEQ ID NO:3); (4)Trp-Gly-Lys(SEQ ID NO:4); (5)Ala-Ala-Trp-Gly-Lys(SEQ ID NO:5); 和(6)Phe-Glu-Ser(SEQ ID NO:6)。
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