专利检索 ap:("Kyriacos C. Nicolaou" OR "Aijun Liu") AND inv:"Aijun Liu" 第 1 页

1.

发明授权
Designed quinone- and hydroquinone-containing cyclic enediyneols and enediyneones having DNA cleaving and cytotoxic properties 失效
标题翻译：设计含有醌和氢醌的环烯雌醇和具有DNA切割和细胞毒性的烯二酮

公开(公告)号：US5274141A

公开(公告)日：1993-12-28

申请号：US938756

申请日：1992-09-01

申请人： Kyriacos C. Nicolaou , Aijun Liu

发明人： Kyriacos C. Nicolaou , Aijun Liu

IPC分类号： C07C39/23 , C07C49/747 , C07C49/755 , C07C50/14 , C07C50/32 , C07C50/34 , C07C50/38 , C07C69/00 , C07C69/017 , C07F7/18 , C07C50/06 , C07C50/20

CPC分类号： C07F7/1852 , C07C39/23 , C07C49/747 , C07C49/755 , C07C50/14 , C07C50/32 , C07C50/34 , C07C50/38 , C07C69/30 , C07C2102/32 , C07C2103/24

摘要： Quinone- and hydroquinone-containing cyclic enediyneols and enediyneones having 10-carbon atoms in the enediyne-containing ring that cleave DNA are disclosed, as are methods of making and using the same.

摘要翻译： 公开了在含有烯烃的环中具有10个碳原子的含喹啉酮和氢醌的环烯炔酮和烯ene酮，其制备和使用它们的方法。