公开(公告)号：US10463603B2

公开(公告)日：2019-11-05

申请号：US14370826

申请日：2013-01-04

Applicant: L'OREAL

Inventor： Maryline Paris ,  Michelle Rathman Josserand ,  Richard Martin ,  Brigitte Lavaud ,  Pascal Hilaire

IPC: A61K8/97 ,  A61Q5/00 ,  A61Q19/08 ,  A61Q19/00 ,  C12N5/04 ,  A01H5/02 ,  A01H6/74

Abstract: The present invention relates to the cosmetic use of dedifferentiated plant cells of a plant of the Rosa sp. genus, or of an extract or a lyophilizate of said cells, as an active agent for caring for aged skin or aged hair. It also relates to rose dedifferentiated cells, in particular Lancôme rose dedifferentiated cells.

公开(公告)号：US09658212B2

公开(公告)日：2017-05-23

申请号：US14378415

申请日：2013-02-07

Applicant: L'OREAL

Inventor： Bruno Bernard ,  Michelle Rathman Josserand

IPC: G01N33/50 ,  C12Q1/68

CPC classification number: G01N33/5073 ,  C12Q1/6883 ,  C12Q2600/136 ,  C12Q2600/158 ,  G01N33/5023 ,  G01N2333/4703 ,  G01N2333/988 ,  G01N2800/20 ,  G01N2800/7038

Abstract: The present invention relates to a process for evaluating in vitro at least one active agent capable of preserving the functionality of epithelial stem cells, in particular of maintaining or stimulating the growth and/or the density and/or the renewal of a keratin material, consisting in determining the ability of the active agent(s) to mimic a hypoxic state in the keratin material, the active agent(s) being capable of increasing the expression of at least carbonic anhydrase IX as biological marker of hypoxia, in the keratin material treated with the active agent(s) compared with the keratin material not treated with the active agent(s). It also relates to the use of such a process.

公开(公告)号：US20140356310A1

公开(公告)日：2014-12-04

申请号：US14370826

申请日：2013-01-04

Applicant: L'OREAL

Inventor： Maryline Paris ,  Michelle Rathman Josserand ,  Richard Martin ,  Brigitte Lavaud ,  Pascal Hilaire

IPC: A61K8/97 ,  C12N5/04 ,  A61Q19/08 ,  A61Q5/00 ,  A61Q19/00

CPC classification number: A61K8/97 ,  A01H5/02 ,  A01H6/749 ,  A61Q5/00 ,  A61Q5/002 ,  A61Q19/00 ,  A61Q19/08 ,  C12N5/04

Abstract: The present invention relates to the cosmetic use of dedifferentiated plant cells of a plant of the Rosa sp. genus, or of an extract or a lyophilisate of said cells, as an active agent for caring for aged skin or aged hair. It also relates to rose dedifferentiated cells, in particular Lancôme rose dedifferentiated cells.

Abstract translation: 本发明涉及Rosa sp。植物的去分化植物细胞的化妆品用途。 属或所述细胞的提取物或冻干物，作为用于照顾老化的皮肤或老化头发的活性剂。 它还涉及玫瑰去分化细胞，特别是兰花玫瑰去分化细胞。