公开(公告)号：US09980893B2

公开(公告)日：2018-05-29

申请号：US15106083

申请日：2014-12-19

Applicant: L'OREAL

Inventor： Aziz Fadli ,  Stéphane Blais

IPC: A61Q5/10 ,  A61K8/49 ,  C07D471/04 ,  A61Q5/06

CPC classification number: A61K8/494 ,  A61K2800/4324 ,  A61Q5/065 ,  A61Q5/10 ,  C07D471/04

Abstract: The invention relates to a 1,2,3,4-tetrahydropyrido[2,3-b]pyrazin-7-amine compound of formula (I) below, addition salts thereof, optical isomers, geometrical isomers and tautomers thereof and/or solvates thereof: in which: .R2, R3, R4, R5, and R7 independently represent: a hydrogen or halogen atom; a C1-C4 alkyl radical; a C1-C4 hydroxyalkyl radical; a carboxyl radical; a (C1-C4)alkoxycarbonyl radical; .R1 and R6, which may be identical or different, represent: hydrogen atom; C1-C10 and preferably Ci-C6 alkyl radical,—optionally interrupted with one or more heteroatoms chosen from O and S or with one or more groups—NR and/or—optionally terminating with at least one group—NX1X2 or at least one group —OX3, .X1 and X2 independently denote—a hydrogen atom, a linear C1-C6 alkyl radical, a branched C3-C6 alkyl radical, a linear C1-C6 hydroxyalkyl radical or a branched C3-C6 hydroxyalkyl radical, X1 and X2 may form, with the nitrogen atom that bears them, a saturated or unsaturated 5- to 8-membered heterocycle, in which one of the ring members may be a heteroatom chosen from O, S and N; the said heterocycle possibly being substituted with one or more linear or branched C1-C4 alkyl or C1-C4 hydroxyalkyl radicals, .X3 denotes—a hydrogen atom—a linear C1-C4 or branched C3-C4 alkyl radical, and .R denotes—a hydrogen atom—a linear C1-C4 alkyl radical.

公开(公告)号：US11504318B2

公开(公告)日：2022-11-22

申请号：US16467591

申请日：2017-12-15

Applicant: L'OREAL

Inventor： Stéphane Sabelle ,  Stéphane Blais ,  Aziz Fadli

IPC: A61Q5/10 ,  A61K8/49 ,  A61K8/41 ,  A61K8/46 ,  C09B55/00

Abstract: The present invention relates to a process for dyeing keratin fibres, in particular human keratin fibres such as the hair, in one or more steps, comprising the application to said keratin fibres of a composition comprising one or more compounds of formula (I) and/or (II), and also to the use thereof for dyeing keratin fibres, and to a device: in which formula (I) or (II) R1, R3, R4, R5, R6, and n are as defined in the description. The compounds of formula (I) according to the invention can give powerful, chromatic and sparingly selective colourings with good colour build-up, which are resistant to the various attacking factors to which keratin fibres may be subjected, such as inclement weather, light, washing and perspiration.

公开(公告)号：US10731038B2

公开(公告)日：2020-08-04

申请号：US16309296

申请日：2017-06-21

Applicant: L'OREAL

Inventor： Stéphane Sabelle ,  Stéphane Blais ,  Aziz Fadli

IPC: A61Q5/10 ,  C09B55/00 ,  A61K8/49 ,  C07D471/04 ,  C07D519/00 ,  C09B53/02

Abstract: The subject of the present invention is symmetric or dissymetric azomethine direct dyes comprising at least one pyrazolopyridine unit of formula (I), a composition comprising said dyes, a process for treating keratin fibers using said dyes, a process for preparing these compounds, synthesis intermediates and a kit. In which formula (I) X, Y1, Y2, Z1, and R1 to R5 are as defined in the description.

公开(公告)号：US10927259B2

公开(公告)日：2021-02-23

申请号：US16467352

申请日：2017-12-15

Applicant: L'OREAL

Inventor： Stéphane Sabelle ,  Stéphane Blais ,  Aziz Fadli

IPC: C09B55/00 ,  A61K8/41 ,  A61K8/46 ,  A61K8/49 ,  A61Q5/06

Abstract: The present invention relates to dissymmetric azomethine direct dyes of formula (I) and the leuco forms thereof of formula (II), and also to the use thereof for dyeing keratin fibres, in particular human keratin fibres such as the hair: in which formula (I) or (II) R1, R2, R3, R4, R5, R6, n and n′ are as defined in the description. The compounds of formula (I) or (II) according to the invention can give powerful, chromatic and sparingly selective colourings with good colour build-up, which are resistant to the various attacking factors to which keratin fibres may be subjected, such as inclement weather, light, washing and perspiration.

公开(公告)号：US10889718B2

公开(公告)日：2021-01-12

申请号：US16470155

申请日：2017-12-15

Applicant: L'Oreal

Inventor： Stéphane Blais ,  Stéphane Sabelle ,  Aziz Fadli

IPC: A61Q5/10 ,  C09B55/00 ,  A61K8/41 ,  A61K8/49 ,  A61Q5/06

Abstract: The present invention relates to novel cationic azomethine direct dyes of formula (I) and the leuco forms thereof of formula (II), and also to the use thereof for dyeing keratin fibres, in particular human keratin fibres such as the hair: (I) (II) in which formula (I) or (II) X1, X2, R1, R2, R3, R4, R5, R6, n and n′ are as defined in the description. The compounds of formula (I) according to the invention can give powerful, chromatic and sparingly selective colourings with good colour build-up, which are resistant to the various attacking factors to which keratin fibres may be subjected, such as inclement weather, light, washing and perspiration.