公开(公告)号：US20200181571A1

公开(公告)日：2020-06-11

申请号：US16462346

申请日：2017-12-13

Applicant: L'OREAL

Inventor： Theebah SELLATHURAI ,  Khalid BAKKAR

IPC: C12N5/071 ,  C12N5/0775

Abstract: The invention relates to the use of germ cells for obtaining a micro hair follicle and to the use thereof for evaluating the effect of cosmetic, pharmaceutical or dermatological products and also for the prophylactic or therapeutic treatment of a state of reduced pilosity.

公开(公告)号：US20200255801A1

公开(公告)日：2020-08-13

申请号：US16760109

申请日：2018-10-30

Applicant: L'OREAL

Inventor： Khalid BAKKAR ,  Theebah SELLATHURAI

IPC: C12N5/071 ,  G01N33/50 ,  A61K35/36

Abstract: The invention relates to a process for the in vitro preparation of a dermal papilla equivalent from fibroblasts derived from the dermal papilla and/or from the connective tissue sheath; to a process for the in vitro preparation of a hair follicle equivalent by culturing proliferative epithelial cells on said dermal papillae thus obtained; to the in vitro dermal papilla and hair follicle equivalents produced by means of the abovementioned processes, and to the uses thereof for treating alopecia and for evaluating the effect of cosmetic, pharmaceutical or dermatological products.