公开(公告)号：US20230346821A1

公开(公告)日：2023-11-02

申请号：US18203828

申请日：2023-05-31

申请人： LEMONEX INC.

发明人： Cheol Hee WON ,  Jun KIM

IPC分类号： A61K31/7105 ,  A61K47/69 ,  A61K47/54 ,  A61K31/713 ,  A61P35/00

CPC分类号： A61K31/7105 ,  A61K31/713 ,  A61K47/549 ,  A61K47/6923 ,  A61P35/00 ,  B82Y5/00

摘要： A nucleic acid carrier according to an embodiment of the present disclosure includes CpG-ODN-RNA conjugate and a porous silica particle carrying the conjugate inside pores thereof. In this regard, the nucleic acid carrier of the present invention can stably deliver loaded nucleic acid molecules to a body and release the same to a target, thereby increasing Type 1 interferon and exhibiting RNA-inherent functions.

公开(公告)号：US20220143068A1

公开(公告)日：2022-05-12

申请号：US17533533

申请日：2021-11-23

申请人： LEMONEX INC.

发明人： Cheol Hee WON ,  Jun KIM

IPC分类号： A61K31/7105 ,  A61K31/713 ,  A61K47/69 ,  A61P35/00

摘要： A nucleic acid carrier according to an embodiment of the present disclosure includes CpG-ODN-RNA conjugate and a porous silica particle carrying the conjugate inside pores thereof. In this regard, the nucleic acid carrier of the present invention can stably deliver loaded nucleic acid molecules to a body and release the same to a target, thereby increasing Type 1 interferon and exhibiting RNA-inherent functions.

公开(公告)号：US20210228670A1

公开(公告)日：2021-07-29

申请号：US17258312

申请日：2019-07-09

申请人： LEMONEX INC.

发明人： Cheol Hee WON ,  Jun KIM

IPC分类号： A61K36/61 ,  A23L33/105 ,  A61K9/00 ,  A61P27/02

摘要： A composition according to an embodiment of the present disclosure includes a banaba leaf extract, a guava leaf extract or a mixture thereof. The composition inhibits photooxidation of A2E due to blue light, inhibits a death of retinal pigment epithelial cells induced by blue light, and inhibits a damage to outer nuclear layers of visual cells in an animal model with blue light-induced macular degeneration, and thus can be beneficially used as a composition for preventing or treating macular degeneration and as a health functional food for preventing or alleviating macular degeneration.