公开(公告)号：US20180355434A1

公开(公告)日：2018-12-13

申请号：US15781958

申请日：2016-11-30

申请人： LG ELECTRONICS INC. ,  INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY

发明人： Jaehoon LEE ,  Jungsu LEE ,  Changhee LEE ,  Jeeyeon HEO ,  Hyungseok CHOI ,  Siyoung SONG ,  Dawoon JUNG

IPC分类号： C12Q1/6886 ,  G06F19/12 ,  G06F19/24

CPC分类号： C12Q1/6886 ,  C12Q2600/178 ,  G06F19/12 ,  G06F19/24

摘要： The present invention relates to a method for discovery of a novel miRNA biomarker for cancer diagnosis, a biomarker for diagnosis of bile duct cancer or pancreatic cancer which has been discovered through the method for discovery of a biomarker, a method for diagnosing cancer, comprising a step in which cancer is diagnosed when f(x)>0 by substitution of the expression level of the miRNA biomarker, which is detected by the method for discovery of a miRNA biomarker for cancer diagnosis, in a sample into a novel SVM classifier function, a kit for diagnosing bile duct cancer or pancreatic cancer comprising the biomarker for diagnosing bile duct cancer or pancreatic cancer, and a computing device for performing a process of diagnosing cancer when f(x)>0 as a result of a calculation by substitution of the expression level of a miRNA biomarker, which is detected by the method for discovery of a miRNA biomarker for cancer diagnosis, into the novel SVM classifier function.

公开(公告)号：US20160070857A1

公开(公告)日：2016-03-10

申请号：US14785166

申请日：2014-04-16

申请人： LG ELECTRONICS INC. ,  INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY

发明人： Hyungseok CHOI ,  Jeeyeon HEO ,  Siyoung SONG ,  Dawoon JUNG

IPC分类号： G06F19/24 ,  C12Q1/68

CPC分类号： G16B40/00 ,  C12Q1/6806 ,  C12Q1/6886 ,  C12Q2600/178

摘要： Disclosed are a method for extracting a biomarker for diagnosing biliary tract cancer and a computing apparatus therefor, and the biomarker for diagnosing biliary tract cancer and an apparatus for diagnosing biliary tract cancer comprising same. More particularly, disclosed are a method for extracting a biomarker for diagnosing biliary tract cancer using a gene specifically expressed in a biliary tract cancer patient, or a microRNA obtained from blood or a tissue, capable of forming a pair with the gene and a computing apparatus therefor, and the biomarker for diagnosing biliary tract cancer and an apparatus for diagnosing biliary tract cancer comprising same.

摘要翻译： 公开了一种用于诊断胆道癌的生物标志物的方法及其计算装置，以及用于诊断胆道癌的生物标志物和包括其的胆汁癌诊断装置。 更具体地，公开了使用在胆道癌患者中特异性表达的基因或能够与该基因形成一对的血液或组织获得的微RNA提取用于诊断胆道癌的生物标志物的方法，以及计算装置 以及用于诊断胆道癌的生物标志物和用于诊断胆道癌的装置。

公开(公告)号：US20160055297A1

公开(公告)日：2016-02-25

申请号：US14784550

申请日：2014-04-16

申请人： LG ELECTRONICS INC. ,  INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY

发明人： Hyungseok CHOI ,  Jeeyeon HEO ,  Yongjin CHOI ,  Haeseok EO ,  Siyoung SONG ,  Dawoon JUNG

IPC分类号： G06F19/24 ,  C40B30/02

CPC分类号： G16B40/00 ,  C12Q1/6886 ,  C12Q2600/158 ,  C12Q2600/178 ,  G01N33/57438 ,  G16B20/00 ,  G16B35/00 ,  G16C20/60

摘要： Disclosed are a method for extracting a biomarker for diagnosing pancreatic cancer, a computing device therefor, a biomarker for diagnosing pancreatic cancer and a device for diagnosing pancreatic cancer including the same. More particularly, disclosed are a method for extracting a biomarker for diagnosing pancreatic cancer using genes specifically expressed in pancreatic cancer patients or microRNAs obtained from blood or tissues paired with the genes, a computing device therefor, a biomarker for diagnosing pancreatic cancer and a device for diagnosing pancreatic cancer including the same.

摘要翻译： 本发明提供一种用于诊断胰腺癌的生物标志物的方法，其计算装置，用于诊断胰腺癌的生物标志物和包括其的用于诊断胰腺癌的装置。 更具体地，公开了使用在胰腺癌患者中特异性表达的基因或从与该基因配对的血液或组织获得的微RNA提取用于诊断胰腺癌的生物标志物的方法，其计算装置，用于诊断胰腺癌的生物标志物 诊断包括胰腺癌的胰腺癌。