公开(公告)号：US10064943B2

公开(公告)日：2018-09-04

申请号：US14728247

申请日：2015-06-02

Applicant: LI-COR, INC.

Inventor： David L. Dilley ,  Joy Kovar

IPC: A61K41/00 ,  A61K49/00 ,  A61K51/08 ,  A61K47/48 ,  A61N5/06 ,  A61M1/36 ,  A61K51/04 ,  A61K47/64 ,  A61K47/68

Abstract: The present invention provides compositions and methods of use of nanoparticle-based probes for in vivo imaging and therapy. The probes can be used to track diseased target cells by non-invasive imaging in the near-infrared range. Additionally, the probes can induce cell death of the target cells via photodynamic treatment.

公开(公告)号：US20180339048A1

公开(公告)日：2018-11-29

申请号：US16046748

申请日：2018-07-26

Applicant: LI-COR, Inc.

Inventor： David L. Dilley ,  Joy Kovar

IPC: A61K41/00 ,  A61N5/06 ,  A61M1/36 ,  A61K51/08 ,  A61K51/04 ,  A61K49/00 ,  A61K47/68 ,  A61K47/64

Abstract: The present invention provides compositions and methods of use of nanoparticle-based probes for in vivo imaging and therapy. The probes can be used to track diseased target cells by non-invasive imaging in the near-infrared range. Additionally, the probes can induce cell death of the target cells via photodynamic treatment.