公开(公告)号：US20130268207A1

公开(公告)日：2013-10-10

申请号：US13790713

申请日：2013-03-08

Applicant: LIFE TECHNOLOGIES CORPORATION

Inventor： Alexander JOYNER ,  Fiona HYLAND ,  Heinz BREU

IPC: G06F19/22

CPC classification number: G16B30/00

Abstract: Systems and method for identifying somatic mutations can receive first ans second sequence information, determine if a variant present in the first sequencing information is also present in the second sequence information, and identify variants present in the first sequence information are somatic mutations when the variant is either not present in the second sequence information or the presence of the variant in the second sequence information is likely due to a sequencing error.

Abstract translation: 用于鉴定体细胞突变的系统和方法可以接收第一和第二序列信息，确定第一序列信息中存在的变体是否也存在于第二序列信息中，并且鉴定第一序列信息中存在的变体是体细胞突变，当变体为 在第二序列信息中不存在或者存在第二序列信息中的变体可能是由于测序错误。