公开(公告)号：US12226561B2

公开(公告)日：2025-02-18

申请号：US17671353

申请日：2022-02-14

Applicant: Life Technologies Corporation ,  Life Technologies AS

Inventor： Lars Norderhaug ,  Angel Varela-Rohena ,  Nephi D. Jones

IPC: A61M1/36 ,  B01L3/00 ,  B03C1/01 ,  B03C1/28 ,  B03C1/30 ,  C07K16/28 ,  C12M1/00 ,  C12M1/12 ,  C12M1/26 ,  C12M3/00

Abstract: A magnetic particle separation system includes a magnetic field generating device having an upper surface with a receiving area formed thereon; and a magnetic field generating element disposed beneath the upper surface, the magnetic field generating element being configured to produce a magnetic field above the upper surface. A container assembly is disposed on the upper surface and includes: a flexible container having an outer wall with an interior surface that at least partially bounds an internal compartment, the outer wall having a front side and an opposing back side with the internal compartment disposed therebetween; a fluid inlet extending through the outer wall at the front side; a fluid outlet extending through the outer wall at the front side; and a first partition projecting into the internal compartment from the front side between the fluid inlet and the fluid outlet.

公开(公告)号：US20170313772A1

公开(公告)日：2017-11-02

申请号：US15433181

申请日：2017-02-15

Applicant: LIFE TECHNOLOGIES CORPORATION

Inventor： Karoline Schjetne ,  Tanja Aarvak ,  Lars Norderhaug

IPC: C07K16/28 ,  C07K16/00 ,  C12N5/0783

CPC classification number: C07K16/2803 ,  C07K16/00 ,  C07K16/2809 ,  C07K16/2896 ,  C07K2317/53 ,  C07K2317/55 ,  C12N5/0636

Abstract: Provided are methods and composition useful in isolating or otherwise preparing a population of target cells. In part, it relates to recombinant antibodies comprising an exogenous proteolytic cleavage site and nucleic acid molecules encoding the antibodies.

公开(公告)号：US20250144280A1

公开(公告)日：2025-05-08

申请号：US19018930

申请日：2025-01-13

Applicant: Life Technologies Corporation ,  Life Technologies AS

Inventor： Lars Norderhaug ,  Nephi D. Jones ,  Angel Varela-Rohena

IPC: A61M1/36 ,  B01L3/00 ,  B03C1/01 ,  B03C1/28 ,  B03C1/30 ,  C07K16/28 ,  C12M1/00 ,  C12M1/12 ,  C12M1/26 ,  C12M3/00

Abstract: A magnetic particle separation system includes a magnetic field generating device having an upper surface with a receiving area formed thereon; and a magnetic field generating element disposed beneath the upper surface, the magnetic field generating element being configured to produce a magnetic field above the upper surface. A container assembly is disposed on the upper surface and includes: a flexible container having an outer wall with an interior surface that at least partially bounds an internal compartment, the outer wall having a front side and an opposing back side with the internal compartment disposed therebetween; a fluid inlet extending through the outer wall at the front side; a fluid outlet extending through the outer wall at the front side; and a first partition projecting into the internal compartment from the front side between the fluid inlet and the fluid outlet.

公开(公告)号：US20220162531A1

公开(公告)日：2022-05-26

申请号：US17671353

申请日：2022-02-14

Applicant: Life Technologies Corporation ,  Life Technologies AS

Inventor： Lars Norderhaug ,  Angel Varela-Rohena ,  Nephi D. Jones

IPC: C12M1/26 ,  B03C1/30 ,  B03C1/01 ,  B03C1/28 ,  A61M1/36 ,  B01L3/00 ,  C12M3/00 ,  C12M1/00 ,  C12M1/12

Abstract: A magnetic particle separation system includes a magnetic field generating device having an upper surface with a receiving area formed thereon; and a magnetic field generating element disposed beneath the upper surface, the magnetic field generating element being configured to produce a magnetic field above the upper surface. A container assembly is disposed on the upper surface and includes: a flexible container having an outer wall with an interior surface that at least partially bounds an internal compartment, the outer wall having a front side and an opposing back side with the internal compartment disposed therebetween; a fluid inlet extending through the outer wall at the front side; a fluid outlet extending through the outer wall at the front side; and a first partition projecting into the internal compartment from the front side between the fluid inlet and the fluid outlet.