公开(公告)号：US20240310319A1

公开(公告)日：2024-09-19

申请号：US18671069

申请日：2024-05-22

Applicant: LIFE TECHNOLOGIES CORPORATION

Inventor： John DONOHUE ,  Sungjoon KIM

IPC: G01N27/414 ,  C12Q1/6869

CPC classification number: G01N27/414 ,  C12Q1/6869

Abstract: A manifestation of fluid potential noise is a periodic profile characterized by a periodic saw-tooth spike in a graph of average voltage across all columns of a sensor array as a function of time. This periodic profile is indicative of an adverse impact on the function of active sensor pixels that are proximal to reference pixels in sensor devices that include a large array of chemically-sensitive field effect transistor (ChemFET) sensors. Systems, devices, and methods are described that can mitigate the impact of reference pixels on fluid potential noise.