公开(公告)号：US11752114B2

公开(公告)日：2023-09-12

申请号：US16386458

申请日：2019-04-17

Applicant: LTS LOHMANN Therapie-Systeme AG

Inventor： Florian Hammes ,  Tobias Kleudgen ,  Anja Tomeleri

IPC: A61K31/135 ,  A61K9/70 ,  A61P25/24

CPC classification number: A61K31/135 ,  A61K9/7084 ,  A61K9/7053 ,  A61P25/24

Abstract: The present invention concerns a transdermal therapeutic system, comprising a backing layer, which is not permeable for the active ingredient, and a matrix layer on one side of the backing layer, wherein the matrix layer contains at least one pressure sensitive adhesive and ketamine or a pharmaceutically acceptable salt or solvate thereof, wherein the at least one pressure sensitive adhesive has free hydroxyl groups, as well as its use as medicament, in particular for the treatment of depression and pain.

公开(公告)号：US11291745B2

公开(公告)日：2022-04-05

申请号：US16239862

申请日：2019-01-04

Applicant: LTS Lohmann Therapie-Systeme AG

Inventor： Michael Horstmann ,  Christian Hausen ,  Patrick Mohr ,  Karin Ludwig ,  Tobias Kleudgen

IPC: A61L15/44 ,  A61L15/24 ,  A61L15/58

Abstract: Adhesive bandages are provided with a water-vapor permeable back layer and an adhesive layer, in which the adhesive layer includes 10 weight percent of a disperse internal phase of hydrophilic particles that are water-swellable in an outer phase that includes at least 10 weight percent of a styrene block copolymer and at least 20 weight percent of an ester resin of colophony, and that can further contain at least one anti-virus substance.