DETECTION OF METHICILLIN-RESISTANT AND METHICILLIN-SENSITIVE STAPHYLOCOCCUS AUREUS IN BIOLOGICAL SAMPLES
    1.
    发明申请
    DETECTION OF METHICILLIN-RESISTANT AND METHICILLIN-SENSITIVE STAPHYLOCOCCUS AUREUS IN BIOLOGICAL SAMPLES 有权
    在生物样品中检测甲硫氨酸耐药和甲基纤维素敏感性油菜

    公开(公告)号:US20090035780A1

    公开(公告)日:2009-02-05

    申请号:US12177075

    申请日:2008-07-21

    IPC分类号: C12Q1/68

    CPC分类号: C12Q1/689 C12Q2600/16

    摘要: Disclosed are methods of identifying a methicillin-resistant Staphylococcus aureus (MRSA) or methicillin-sensitive Staphylococcus aureus (MSSA) in a sample. The present invention provides a diagnostic method comprising modification of sequences of S. aureus by converting non-methylated cytosine residues ultimately into thymidine residues in the target nucleic acid. The invention further provides for the detection of modified sequences derived from the spa gene, the mecA gene, and the integrated SCCmec cassette of S. aureus.

    摘要翻译: 公开了在样品中鉴定耐甲氧西林金黄色葡萄球菌(MRSA)或甲氧西林敏感性金黄色葡萄球菌(MSSA)的方法。 本发明提供了一种诊断方法,其包括通过将非甲基化胞嘧啶残基最终转移到靶核酸中的胸苷残基来修饰金黄色葡萄球菌的序列。 本发明进一步提供了检测源自温泉基因,mecA基因和金黄色葡萄球菌综合SCCmec盒的修饰序列。

    Detection of methicillin-resistant and methicillin-sensitive Staphylococcus aureus in biological samples
    2.
    发明授权
    Detection of methicillin-resistant and methicillin-sensitive Staphylococcus aureus in biological samples 有权
    在生物样品中检测耐甲氧西林和甲氧西林敏感性金黄色葡萄球菌

    公开(公告)号:US07888075B2

    公开(公告)日:2011-02-15

    申请号:US12177075

    申请日:2008-07-21

    IPC分类号: C12Q1/68 C12P19/34

    CPC分类号: C12Q1/689 C12Q2600/16

    摘要: Disclosed are methods of identifying a methicillin-resistant Staphylococcus aureus (MRSA) or methicillin-sensitive Staphylococcus aureus (MSSA) in a sample. The present invention provides a diagnostic method comprising modification of sequences of S. aureus by converting non-methylated cytosine residues ultimately into thymidine residues in the target nucleic acid. The invention further provides for the detection of modified sequences derived from the spa gene, the mecA gene, and the integrated SCCmec cassette of S. aureus.

    摘要翻译: 公开了在样品中鉴定耐甲氧西林金黄色葡萄球菌(MRSA)或甲氧西林敏感性金黄色葡萄球菌(MSSA)的方法。 本发明提供了一种诊断方法,其包括通过将非甲基化胞嘧啶残基最终转移到靶核酸中的胸苷残基来修饰金黄色葡萄球菌的序列。 本发明进一步提供了检测源自温泉基因,mecA基因和金黄色葡萄球菌综合SCCmec盒的修饰序列。