专利检索 ap:("Laszlo Vertesy" OR "Martin Knauf" OR "Astrid Markus-Erb" OR "Luigi Toti" OR "Marie-Cecile Raynal-Wetzel" OR "Florence Fassy") AND inv:"Marie-Cecile Raynal-Wetzel" 第 1 页

1.

发明授权
Coniosetin and derivatives thereof, process for the preparation and the use thereof 有权
标题翻译：洋葱素及其衍生物，其制备方法和用途

公开(公告)号：US06599930B2

公开(公告)日：2003-07-29

申请号：US10003413

申请日：2001-12-06

申请人： Laszlo Vertesy , Martin Knauf , Astrid Markus-Erb , Luigi Toti , Marie-Cecile Raynal-Wetzel , Florence Fassy

发明人： Laszlo Vertesy , Martin Knauf , Astrid Markus-Erb , Luigi Toti , Marie-Cecile Raynal-Wetzel , Florence Fassy

IPC分类号： A61K3142

CPC分类号： C07D207/44

摘要： The present invention relates to novel active substances (coniosetin and coniosetin derivatives) of the formula I which are produced by the microorganism Coniochaeta ellipsoidea Udagawa (DSM 13856) during fermentation, wherein R, R2, R3, R4, R5, X, X2, X3 and X4 have the meanings stated in the specification, to chemical derivatives of coniosetin, to a process for their preparation and to their use as pharmaceuticals.

摘要翻译： 本发明涉及在发酵过程中由微生物Coniochaeta ellipsoidea Udagawa（DSM 13856）生产的式I的新型活性物质（coniosetin和conisonetin衍生物），其中R，R2，R3，R4，R5，X，X2，X3和 X4具有说明书中所述的含义，对于曲妥单抗的化学衍生物，其制备方法及其作为药物的用途。