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公开(公告)号:US06783954B2
公开(公告)日:2004-08-31
申请号:US09884050
申请日:2001-06-20
申请人: Liat Mintz , Kinneret Savitzky , Sharon Engel
发明人: Liat Mintz , Kinneret Savitzky , Sharon Engel
IPC分类号: C12N1500
摘要: The invention concerns novel nucleic acid sequences and amino acid sequences of a novel variant of vascular endothelial growth factor (VEGF). The invention further concerns expression vectors and host cells containing said sequences as well as pharmaceutical compositions and detection methods using said sequences.
摘要翻译: 本发明涉及血管内皮生长因子(VEGF)的新型变体的新型核酸序列和氨基酸序列。 本发明还涉及含有所述序列的表达载体和宿主细胞以及使用所述序列的药物组合物和检测方法。
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公开(公告)号:US06720182B1
公开(公告)日:2004-04-13
申请号:US09569611
申请日:2000-05-10
申请人: Kinneret Savitzky , Liat Mintz , Sharon Engel , Jeanne Bernstein
发明人: Kinneret Savitzky , Liat Mintz , Sharon Engel , Jeanne Bernstein
IPC分类号: C07H2104
CPC分类号: C07H21/04 , A61K38/00 , C07K14/70578
摘要: The invention concerns novel nucleic acid sequences and amino acid sequences obtained by alternative splicing, expression vectors, host cell and pharmaceutical compositions comprising said sequences.
摘要翻译: 本发明涉及通过选择性剪接获得的新型核酸序列和氨基酸序列,表达载体,宿主细胞和包含所述序列的药物组合物。
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公开(公告)号:US06506884B1
公开(公告)日:2003-01-14
申请号:US09519476
申请日:2000-03-06
申请人: Liat Mintz , Kinneret Savitzky , Sharon Engel
发明人: Liat Mintz , Kinneret Savitzky , Sharon Engel
IPC分类号: A61K3818
摘要: The invention concerns novel nucleic acid sequences and amino acid sequences of a novel variant of vascular endothelial growth factor (VEGF). The invention further concerns expression vectors and host cells containing said sequences as well as pharmaceutical compositions and detection methods using said sequences.
摘要翻译: 本发明涉及血管内皮生长因子(VEGF)的新型变体的新型核酸序列和氨基酸序列。 本发明还涉及含有所述序列的表达载体和宿主细胞以及使用所述序列的药物组合物和检测方法。
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公开(公告)号:US06740516B2
公开(公告)日:2004-05-25
申请号:US09755100
申请日:2001-01-08
申请人: Kinneret Savitzky , Liat Mintz , Anat David , Idit Azar
发明人: Kinneret Savitzky , Liat Mintz , Anat David , Idit Azar
IPC分类号: C12H120
CPC分类号: C12N9/6445
摘要: An isolated nucleic acid sequence depicted in SEQ ID NO:6 is an alternative splice variant of human kallikrien-2 gene (KLK-2). An expression vector containing the splice variant and a host cell transfected by the expression vector are provided. The nucleic acid is useful for determining the level of nucleic acid sequences of human kallikrien variants in a biological sample.
摘要翻译: SEQ ID NO:6中所示的分离的核酸序列是人类kallikrien-2基因(KLK-2)的选择性剪接变体。 提供含有剪接变体和由表达载体转染的宿主细胞的表达载体。 核酸可用于确定生物样品中人类激素变体的核酸序列的水平。
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公开(公告)号:US06994994B1
公开(公告)日:2006-02-07
申请号:US10031607
申请日:2000-07-19
申请人: Kinneret Savitzky , Rami Khosravi , Menashe Elazar
发明人: Kinneret Savitzky , Rami Khosravi , Menashe Elazar
CPC分类号: C07K14/70578 , A61K38/00 , A61K39/00 , A61K48/00 , A61K2121/00
摘要: The present invention concerns six novel variants of alternative splicing of the CD40 receptor.
摘要翻译: 本发明涉及CD40受体的选择性剪接的六种新型变体。
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公开(公告)号:US20050244877A1
公开(公告)日:2005-11-03
申请号:US11132839
申请日:2005-05-18
申请人: Kinneret Savitzky , Rami Khosravi , Menashe Elazar
发明人: Kinneret Savitzky , Rami Khosravi , Menashe Elazar
IPC分类号: G01N33/50 , A61K35/74 , A61K35/76 , A61K38/00 , A61K39/00 , A61K39/395 , A61K48/00 , A61P19/02 , A61P25/00 , A61P29/00 , A61P37/02 , C07K14/705 , C07K16/28 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N15/09 , C12N15/12 , C12Q1/68 , G01N33/15 , G01N33/53 , G01N33/566 , G01N37/00 , A61K38/17 , C07H21/04 , C07K14/72
CPC分类号: C07K14/70578 , A61K38/00 , A61K39/00 , A61K48/00 , A61K2121/00
摘要: The present invention concerns six novel variants of alternative splicing of the CD40 receptor.
摘要翻译: 本发明涉及CD40受体的选择性剪接的六种新型变体。
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