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公开(公告)号：US08510057B1
公开(公告)日：2013-08-13
申请号：US12151977
申请日：2008-05-08
申请人： Linda Avey , Andro Rene Hsu , Oleksiy Khomenko , John Michael Macpherson , Joanna Louise Mountain , Brian Thomas Naughton , Serge Saxonov , Anne Wojcicki , Alexander Wong
发明人： Linda Avey , Andro Rene Hsu , Oleksiy Khomenko , John Michael Macpherson , Joanna Louise Mountain , Brian Thomas Naughton , Serge Saxonov , Anne Wojcicki , Alexander Wong
IPC分类号： G06F7/00
摘要： Summarizing an aggregate contribution to a characteristic for an individual is disclosed, including determining the characteristic to be evaluated, identifying one or more markers associated with the characteristic, retrieving the measurement of the individual for each of the one or more markers from a database of individuals' markers, retrieving a statistical factor that measures the association between the marker associated with the characteristic and the characteristic for each of the one or more markers from the marker database, and determining the aggregate contribution based at least in part on the retrieved statistical factors.
摘要翻译： 公开了对个体的特征的总体贡献的总结，包括确定要评估的特征，识别与特征相关联的一个或多个标记，从个体数据库中检索针对一个或多个标记中的每一个的个体的测量 标记，检索测量与特征相关联的标记与来自标记数据库的一个或多个标记中的每一个的特征的关联的统计因子，以及至少部分地基于所检索的统计因素来确定总贡献。
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公开(公告)号：US20090118131A1
公开(公告)日：2009-05-07
申请号：US12288026
申请日：2008-10-15
申请人： Linda Avey , Oleksiy Khomenko , Brian Thomas Naughton , Serge Saxonov , Anne Wojcicki , Alexander Wong
发明人： Linda Avey , Oleksiy Khomenko , Brian Thomas Naughton , Serge Saxonov , Anne Wojcicki , Alexander Wong
摘要： Displaying a comparison of genotypic information between relatives is disclosed, including receiving an indication that a first individual is a grandparent, receiving an indication that a second individual is a grandchild of the first individual, comparing the genotypic information of the first individual and the second individual and calculating a similarity score, and displaying an indication of the similarity score graphically using colors.
摘要翻译： 公开了显示亲属之间的基因型信息的比较，包括接收第一个体是祖父母的指示，接收第二个体是第一个体的孙子的指示，比较第一个体和第二个体的基因型信息 以及计算相似性得分，并使用颜色以图形方式显示相似性得分的指示。
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公开(公告)号：US09864835B2
公开(公告)日：2018-01-09
申请号：US12288026
申请日：2008-10-15
申请人： Linda Avey , Oleksiy Khomenko , Brian Thomas Naughton , Serge Saxonov , Anne Wojcicki , Alexander Wong
发明人： Linda Avey , Oleksiy Khomenko , Brian Thomas Naughton , Serge Saxonov , Anne Wojcicki , Alexander Wong
摘要： Displaying a comparison of genotypic information between relatives is disclosed, including receiving an indication that a first individual is a grandparent, receiving an indication that a second individual is a grandchild of the first individual, comparing the genotypic information of the first individual and the second individual and calculating a similarity score, and displaying an indication of the similarity score graphically using colors.
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公开(公告)号：US10275569B2
公开(公告)日：2019-04-30
申请号：US12288096
申请日：2008-10-15
申请人： Linda Avey , Oleksiy Khomenko , Brian Thomas Naughton , Serge Saxonov , Anne Wojcicki , Alexander Wong
发明人： Linda Avey , Oleksiy Khomenko , Brian Thomas Naughton , Serge Saxonov , Anne Wojcicki , Alexander Wong
摘要： Displaying a comparison of genetic data is disclosed, including receiving an indication of a first individual, receiving an indication of a second individual, retrieving the genotypic information for the first individual and the second individual, comparing the genotypic information of the first individual and the second individual, displaying an indication of the comparison of the genotypic information of the first individual and the second individual graphically. A first graphical symbol is used to display an indication of the genome regions for which the first individual and the second individual are identical. A second graphical symbol is used to display an indication of the genome regions for which the first individual and the second individual are half identical.
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公开(公告)号：US20090119083A1
公开(公告)日：2009-05-07
申请号：US12288096
申请日：2008-10-15
申请人： Linda Avey , Oleksiy Khomenko , Brian Thomas Naughton , Serge Saxonov , Anne Wojcicki , Alexander Wong
发明人： Linda Avey , Oleksiy Khomenko , Brian Thomas Naughton , Serge Saxonov , Anne Wojcicki , Alexander Wong
IPC分类号： G06G7/48
摘要： Displaying a comparison of genetic data is disclosed, including receiving an indication of a first individual, receiving an indication of a second individual, retrieving the genotypic information for the first individual and the second individual, comparing the genotypic information of the first individual and the second individual, displaying an indication of the comparison of the genotypic information of the first individual and the second individual graphically. A first graphical symbol is used to display an indication of the genome regions for which the first individual and the second individual are identical. A second graphical symbol is used to display an indication of the genome regions for which the first individual and the second individual are half identical.
摘要翻译： 公开了显示遗传数据的比较，包括接收第一个体的指示，接收第二个体的指示，检索第一个体和第二个体的基因型信息，比较第一个体和第二个体的基因型信息 个体，以图形方式显示第一个体和第二个体的基因型信息的比较的指示。 第一图形符号用于显示第一个体和第二个体相同的基因组区域的指示。 第二个图形符号被用于显示第一个体和第二个体是一半相同的基因组区域的指示。
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公开(公告)号：US20100223281A1
公开(公告)日：2010-09-02
申请号：US12644791
申请日：2009-12-22
申请人： Lawrence Hon , Serge Saxonov , Brian Thomas Naughton , Joanna Louise Mountain , Anne Wojcicki , Linda Avey
发明人： Lawrence Hon , Serge Saxonov , Brian Thomas Naughton , Joanna Louise Mountain , Anne Wojcicki , Linda Avey
IPC分类号： G06F17/30
CPC分类号： G06F19/14 , G06F17/30522 , G06F17/30867 , G06F19/22 , G06F19/28 , G06N5/048
摘要： Determining relative relationship includes receiving recombinable deoxyribonucleic acid (DNA) information of a first user and recombinable DNA information of a second user, determining, based at least in part on the recombinable DNA information of the first user and recombinable DNA information of the second user, a predicted degree of relationship between the first user and the second user, and in the event that the expected degree of relationship between the first user and the second user at least meets the threshold, notifying at least the first user about a relative relationship with the second user.
摘要翻译： 确定相对关系包括接收第一用户的可重复脱氧核糖核酸（DNA）信息和第二用户的可重复DNA信息，至少部分基于第一用户的可重复DNA信息和第二用户的可重复DNA信息， 第一用户和第二用户之间的预测关系程度，并且在第一用户和第二用户之间的预期关系程度至少满足阈值的情况下，至少通知第一用户关于与第 第二个用户
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公开(公告)号：US08463554B2
公开(公告)日：2013-06-11
申请号：US12644791
申请日：2009-12-22
申请人： Lawrence Hon , Serge Saxonov , Brian Thomas Naughton , Joanna Louise Mountain , Anne Wojcicki , Linda Avey
发明人： Lawrence Hon , Serge Saxonov , Brian Thomas Naughton , Joanna Louise Mountain , Anne Wojcicki , Linda Avey
IPC分类号： G06F7/00
CPC分类号： G06F19/14 , G06F17/30522 , G06F17/30867 , G06F19/22 , G06F19/28 , G06N5/048
摘要： Determining relative relationship includes receiving recombinable deoxyribonucleic acid (DNA) information of a first user and recombinable DNA information of a second user, determining, based at least in part on the recombinable DNA information of the first user and recombinable DNA information of the second user, a predicted degree of relationship between the first user and the second user, and in the event that the expected degree of relationship between the first user and the second user at least meets the threshold, notifying at least the first user about a relative relationship with the second user.
摘要翻译： 确定相对关系包括接收第一用户的可重复脱氧核糖核酸（DNA）信息和第二用户的可重复DNA信息，至少部分基于第一用户的可重复DNA信息和第二用户的可重复DNA信息， 第一用户和第二用户之间的预测关系程度，并且在第一用户和第二用户之间的预期关系程度至少满足阈值的情况下，至少通知第一用户关于与第 第二个用户
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公开(公告)号：US08543339B2
公开(公告)日：2013-09-24
申请号：US12592950
申请日：2009-12-04
申请人： Anne Wojcicki , Linda Avey , Joanna Louise Mountain , John Michael Macpherson , Joyce Yeh-hong Tung
发明人： Anne Wojcicki , Linda Avey , Joanna Louise Mountain , John Michael Macpherson , Joyce Yeh-hong Tung
IPC分类号： G06F7/00
摘要： Gamete donor selection includes receiving a specification including a phenotype of interest, receiving a genotype of a recipient and a plurality of genotypes of a respective plurality of donors, determining statistical information pertaining to the phenotype of interest based at least in part on different pairings of the genotype of the recipient and a genotype of a donor in the plurality of donors, and identifying a preferred donor among the plurality of donors, based at least in part on the statistical information determined.
摘要翻译： 配子供体选择包括接收包括感兴趣的表型，接受接受者的基因型和相应的多个供体的多个基因型的规范，至少部分地基于不同的配对，确定与感兴趣的表型有关的统计信息 至少部分地基于所确定的统计信息，接收者的基因型和多个供体中的供体的基因型以及多个供体中的优选给体。
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公开(公告)号：US20100145981A1
公开(公告)日：2010-06-10
申请号：US12592950
申请日：2009-12-04
申请人： Anne Wojcicki , Linda Avey , Joanna Louise Mountain , John Michael Macpherson , Joyce Yeh-hong Tung
发明人： Anne Wojcicki , Linda Avey , Joanna Louise Mountain , John Michael Macpherson , Joyce Yeh-hong Tung
IPC分类号： G06F17/30
摘要： Gamete donor selection includes receiving a specification including a phenotype of interest, receiving a genotype of a recipient and a plurality of genotypes of a respective plurality of donors, determining statistical information pertaining to the phenotype of interest based at least in part on different pairings of the genotype of the recipient and a genotype of a donor in the plurality of donors, and identifying a preferred donor among the plurality of donors, based at least in part on the statistical information determined.
摘要翻译： 配子供体选择包括接收包括感兴趣的表型，接受接受者的基因型和相应的多个供体的多个基因型的规范，至少部分地基于不同的配对，确定与感兴趣的表型有关的统计信息 至少部分地基于所确定的统计信息，接收者的基因型和多个供体中的供体的基因型以及多个供体中的优选给体。
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公开(公告)号：US20090112871A1
公开(公告)日：2009-04-30
申请号：US12288014
申请日：2008-10-14
申请人： Brian Lee Hawthorne , Oleksiy Khomenko , Jeffrey Mellen , Marcela Miyazawa , Michael Polcari , Jack Tihon , Alexander Wong , Anne Wojcicki , Linda Avey
发明人： Brian Lee Hawthorne , Oleksiy Khomenko , Jeffrey Mellen , Marcela Miyazawa , Michael Polcari , Jack Tihon , Alexander Wong , Anne Wojcicki , Linda Avey
IPC分类号： G06F17/30
CPC分类号： H04L63/101 , G06F15/16 , G06F17/30867 , G06F17/3089 , G06F19/18 , H04L67/306
摘要： Sharing data is disclosed. In some cases, sharing data includes receiving a request to share data from a first account to a second account, receiving an indication of a plurality of first account profiles associated with the first account to share with the second account, and establishing sharing from the plurality of first account profiles to the second account, wherein sharing comprises the second account having read access to a subset of nonpublic data associated with the plurality of first account profiles.
摘要翻译： 公开共享数据。 在一些情况下，共享数据包括接收从第一帐户共享数据到第二帐户的请求，接收与第一帐户相关联的多个第一账户配置文件的指示以与第二账户共享，以及从多个账户建立共享 的第一帐户简档到第二帐户，其中共享包括具有对与多个第一帐户简档相关联的非公开数据的子集的读取访问的第二帐户。
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