Abstract:
Embodiments are directed to methods of evaluating the prognosis of a breast cancer patient by assessing the level of phosphorylation tyrosine 36 of estrogen receptor beta (ERB). Certain embodiments are directed to methods for evaluating the prognosis of a cancer patient comprising contacting a breast cancer sample from a patient with stage II or stage III breast cancer with an antibody that binds phosphorylated tyrosine 36 of Ei¾β; quantifying phosphorylation of tyrosine 36 of EI¾β; and classifying the patient as having a good prognosis if phosphorylated tyrosine 36 levels are elevated or classifying the patient as having a poor prognosis if tyrosine levels are decreased relative to a non-cancer control. Certain embodiments are directed to an antibody or antibodies that specifically bind tyrosine 36 (Y36) of the ERp.
Abstract:
Embodiments provide relevancy-based smart page navigation within an application interface. A container is associated with each page of the interface (e.g., as represented by a tree topology). The container references other pages deemed relevant according to a measure. This relevancy value may be determined from factors such as frequency of accessing the other page, proximity of the other page to the current page, and/or user designation. A home page and/or recently accessed pages may also be included in the container, irrespective of their relevance score. The container, including page thumbnails, is offered to the user. Upon selecting a thumbnail, the user moves directly to that other page, thereby avoiding laborious effort to navigate the tree topology. Embodiments may retain unsaved data of a previous page following navigation away using the container. That unsaved data is thus available for editing if the user seeks to return to the previous page.
Abstract:
A medicament for use in treating hypertension. The medicament is a glycoprotein, a mixture of polysaccharide and protein, a polypeptide or a protein.