-
公开(公告)号：US10801003B2
公开(公告)日：2020-10-13
申请号：US15613954
申请日：2017-06-05
申请人： Lonza Ltd
发明人： Colin Mark Jaques , Mohsan Waseem Khan , Rita D'Ornelas P. De Barros Costa , Anthony Beaney , David Valentine
摘要： A single-use bioreactor is provided. The single-use bioreactor may include a bioprocess container, a shell, at least one agitator, at least one sparger, at least one gas filter inlet port for the sparger(s) and headspace overlay, at least one fill port, at least one harvest port, at least one sample port, and at least one probe. In examples, at least one controller may monitor and control one or more parameters associated with the single-use bioreactor A method to cultivate and propagate mammalian cells is also provided. The method may include cultivating under suitable conditions and in a suitable culture medium in a first single-use bioreactor, transferring the medium containing the cells obtained by propagation from the at least one mammalian cell is into a second single-use bioreactor, transferring the medium containing the cells obtained by propagation from the at least one mammalian cell is into a third single-use bioreactor, and cultivating the cells in the third bioreactor.
-
公开(公告)号：US20180010082A1
公开(公告)日：2018-01-11
申请号：US15712302
申请日：2017-09-22
申请人： Lonza Ltd
发明人： Colin Mark Jaques , Mohsan Waseem Khan , Rita D'Ornelas P. De Barros Costa , Anthony Beaney , David Valentine
CPC分类号： C12M27/20 , B01F3/04106 , B01F7/00033 , B01F7/00375 , B01F7/00633 , B01F7/1675 , B01F15/0085 , B01F2215/0073 , B01F2215/0431 , B01F2215/0459 , C12M1/02 , C12M23/14 , C12M23/26 , C12M23/28 , C12M27/02 , C12M29/00 , C12M29/06
摘要： A single-use bioreactor is provided. The single-use bioreactor may include a bioprocess container, a shell, at least one agitator, at least one sparger, at least one gas filter inlet port for the sparger(s) and headspace overlay, at least one fill port, at least one harvest port, at least one sample port, and at least one probe. In examples, at least one controller may monitor and control one or more parameters associated with the single-use bioreactor A method to cultivate and propagate mammalian cells is also provided. The method may include cultivating under suitable conditions and in a suitable culture medium in a first single-use bioreactor, transferring the medium containing the cells obtained by propagation from the at least one mammalian cell is into a second single-use bioreactor, transferring the medium containing the cells obtained by propagation from the at least one mammalian cell is into a third single-use bioreactor, and cultivating the cells in the third bioreactor.
-
公开(公告)号：US20230045226A1
公开(公告)日：2023-02-09
申请号：US17850452
申请日：2022-06-27
申请人： Lonza Ltd
发明人： Colin Mark Jaques , Mohsan Waseem Khan , Rita D'Ornelas P. De Barros Costa , Anthony Beaney , David Valentine
IPC分类号： C12M1/00 , C12M1/06 , B01F23/231 , B01F27/053 , B01F27/86 , B01F27/191 , B01F27/113 , B01F35/513
摘要： A single-use bioreactor is provided. The single-use bioreactor may include a bioprocess container, a shell, at least one agitator, at least one sparger, at least one gas filter inlet port for the sparger(s) and headspace overlay, at least one fill port, at least one harvest port, at least one sample port, and at least one probe. In examples, at least one controller may monitor and control one or more parameters associated with the single-use bioreactor A method to cultivate and propagate mammalian cells is also provided. The method may include cultivating under suitable conditions and in a suitable culture medium in a first single-use bioreactor, transferring the medium containing the cells obtained by propagation from the at least one mammalian cell is into a second single-use bioreactor, transferring the medium containing the cells obtained by propagation from the at least one mammalian cell is into a third single-use bioreactor, and cultivating the cells in the third bioreactor.
-
公开(公告)号：US11371002B2
公开(公告)日：2022-06-28
申请号：US17019516
申请日：2020-09-14
申请人： Lonza Ltd
发明人： Colin Mark Jaques , Mohsan Waseem Khan , Rita D'Ornelas P. De Barros Costa , Anthony Beaney , David Valentine
IPC分类号： C12M1/00 , C12M1/06 , B01F23/231 , B01F27/053 , B01F27/86 , B01F27/191 , B01F27/113 , B01F35/513
摘要： A single-use bioreactor is provided. The single-use bioreactor may include a bioprocess container, a shell, at least one agitator, at least one sparger, at least one gas filter inlet port for the sparger(s) and headspace overlay, at least one fill port, at least one harvest port, at least one sample port, and at least one probe. In examples, at least one controller may monitor and control one or more parameters associated with the single-use bioreactor A method to cultivate and propagate mammalian cells is also provided. The method may include cultivating under suitable conditions and in a suitable culture medium in a first single-use bioreactor, transferring the medium containing the cells obtained by propagation from the at least one mammalian cell is into a second single-use bioreactor, transferring the medium containing the cells obtained by propagation from the at least one mammalian cell is into a third single-use bioreactor, and cultivating the cells in the third bioreactor.
-
公开(公告)号：US20210002597A1
公开(公告)日：2021-01-07
申请号：US17019516
申请日：2020-09-14
申请人： Lonza Ltd
发明人： Colin Mark Jaques , Mohsan Waseem Khan , Rita D'Ornelas P. De Barros Costa , Anthony Beaney , David Valentine
摘要： A single-use bioreactor is provided. The single-use bioreactor may include a bioprocess container, a shell, at least one agitator, at least one sparger, at least one gas filter inlet port for the sparger(s) and headspace overlay, at least one fill port, at least one harvest port, at least one sample port, and at least one probe. In examples, at least one controller may monitor and control one or more parameters associated with the single-use bioreactor A method to cultivate and propagate mammalian cells is also provided. The method may include cultivating under suitable conditions and in a suitable culture medium in a first single-use bioreactor, transferring the medium containing the cells obtained by propagation from the at least one mammalian cell is into a second single-use bioreactor, transferring the medium containing the cells obtained by propagation from the at least one mammalian cell is into a third single-use bioreactor, and cultivating the cells in the third bioreactor.
-
公开(公告)号：US20170349874A1
公开(公告)日：2017-12-07
申请号：US15613954
申请日：2017-06-05
申请人： Lonza Ltd
发明人： Colin Mark Jaques , Mohsan Waseen Khan , Rita D'Ornelas P. De Barros Costa , Anthony Beaney , David Valentine
摘要： A single-use bioreactor is provided. The single-use bioreactor may include a bioprocess container, a shell, at least one agitator, at least one sparger, at least one gas filter inlet port for the sparger(s) and headspace overlay, at least one fill port, at least one harvest port, at least one sample port, and at least one probe. In examples, at least one controller may monitor and control one or more parameters associated with the single-use bioreactor A method to cultivate and propagate mammalian cells is also provided. The method may include cultivating under suitable conditions and in a suitable culture medium in a first single-use bioreactor, transferring the medium containing the cells obtained by propagation from the at least one mammalian cell is into a second single-use bioreactor, transferring the medium containing the cells obtained by propagation from the at least one mammalian cell is into a third single-use bioreactor, and cultivating the cells in the third bioreactor.
-
-
-
-
-
搜索结果
6 条记录 (耗时 0.016 秒)
