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1.发明授权
公开(公告)号：US5811120A
公开(公告)日：1998-09-22
申请号：US824590
申请日：1997-03-26
申请人： Lowell L. Gibson , Kerry J. Hartauer , Julian L. Stowers , Stephanie A. Sweetana , Arvind L. Thakkar
发明人： Lowell L. Gibson , Kerry J. Hartauer , Julian L. Stowers , Stephanie A. Sweetana , Arvind L. Thakkar
IPC分类号： A61K31/4535 , A61K9/20 , A61K31/445
CPC分类号： A61K31/4535 , Y10S514/96 , Y10S514/962
摘要： This invention provides solid orally administerable pharmaceutical formulations comprising raloxifene hydrochloride, a surfactant being sorbitan fatty acid ester or a polyoxyethylene sorbitan fatty acid ester, polyvinylpyrrolidone, and a water soluble diluent which is polyol or sugar.
摘要翻译： 本发明提供了含有雷洛昔芬盐酸盐，表面活性剂为脱水山梨醇脂肪酸酯或聚氧乙烯脱水山梨醇脂肪酸酯，聚乙烯吡咯烷酮和多元醇或糖的水溶性稀释剂的固体可口服给药的药物制剂。
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2.发明授权
公开(公告)号：US5972383A
公开(公告)日：1999-10-26
申请号：US88695
申请日：1998-06-01
申请人： Lowell L. Gibson , Kerry J. Hartauer , Julian L. Stowers , Stephanie A. Sweetana , Arvind L. Thakkar
发明人： Lowell L. Gibson , Kerry J. Hartauer , Julian L. Stowers , Stephanie A. Sweetana , Arvind L. Thakkar
IPC分类号： A61K9/20 , A61K31/445 , A61K31/4535
CPC分类号： A61K31/4535 , A61K31/445 , A61K9/2013 , A61K9/2018 , Y10S514/96 , Y10S514/962
摘要： This invention provides orally administerable pharmaceutical formulations comprising raloxifene, its ethers or esters, or a pharmaceutically-acceptable salt thereof, in combination with a hydrophilic carrier composition.
摘要翻译： 本发明提供了包含雷洛昔芬，其醚或酯或其药学上可接受的盐与亲水性载体组合物组合的口服给药的药物制剂。
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公开(公告)号：US4847092A
公开(公告)日：1989-07-11
申请号：US233771
申请日：1988-08-19
CPC分类号： A61K9/4866 , A61K9/4858
摘要： This invention provides orally administerable pharmaceutical formulations having a semi-solid matrix containing a hydrophilic substance capable of creating channels in a hydrophobic carrier matrix thereby providing a sustained rate of release of an active agent from the formulation.
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公开(公告)号：US5112619A
公开(公告)日：1992-05-12
申请号：US407097
申请日：1989-09-14
CPC分类号： A61K9/4866 , A61K9/4858
摘要： This invention provides orally administerable pharmaceutical formulations having a semi-solid matrix containing a hydrophilic substance capable of creating channels in a hydrophobic carrier matrix thereby providing a sustained rate of release of an active agent from the formulation.
摘要翻译： 本发明提供具有半固体基质的可口服给药的药物制剂，所述半固体基质含有能够在疏水性载体基质中形成通道的亲水物质，从而提供活性剂从制剂中持续的释放速率。
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公开(公告)号：US4797286A
公开(公告)日：1989-01-10
申请号：US797305
申请日：1985-11-12
CPC分类号： A61K9/4858 , A61K9/4866
摘要： This invention provides orally administerable pharmaceutical formulations having a semi-solid matrix containing a hydrophilic substance capable of creating channels in a hydrophobic carrier matrix thereby providing a sustained rate of release of an active agent from the formulation.
摘要翻译： 本发明提供具有半固体基质的可口服给药的药物制剂，所述半固体基质含有能够在疏水性载体基质中形成通道的亲水物质，从而提供活性剂从制剂中持续的释放速率。
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