摘要:
A system and method for mild cognitive impairment (MCI) class discovery using gene expression data are provided. The method comprises: acquiring gene expression data of a patient having MCI; and identifying a putative MCI subtype based on an expression signature in the gene expression data, wherein the putative MCI subtype is identified by using a boosting tree.
摘要:
A method for diagnosing depression includes providing surface-enhanced laser desorption/ionization mass spectrometric (SELDI-MS) data of a plurality of proteins, said data obtained from a patient and comprising a plurality of peak values, and analyzing said peak values with an alternating decision tree comprising a set of tests of said data peaks values and associated prediction values, wherein said data is predictive of depression if a sum of the prediction values of said tree is greater than 1.0.
摘要:
A system and method for using heterogeneous data from multiple healthcare information sources in a medical decision support system is disclosed. Each healthcare information system stores medical data using a different local schema. The medical decision support system provides responses to user queries. A query is received from a user that is generated in a standardized global schema. The query includes information from medical ontologies. Database queries are generated from the user queries that use the medical ontologies to generate constraints in the queries. The medical ontologies are also used to infer database queries. The generated query is translated into multiple queries for the multiple healthcare systems wherein each query is in the local schema of the healthcare information system that is being queried. Each database query is transmitted to one of the healthcare information systems based on the local schema of the particular query. Data is collected from each of the queried healthcare information system and analyzed. A query response is formulated for the user
摘要:
A method for diagnosing depression includes providing surface-enhanced laser desorption/ionisation mass spectrometric (SELDI-MS) data of a plurality of proteins, said data obtained from a patient and comprising a plurality of peak values, and analysing said peak values with an alternating decision tree comprising a set of tests of said data peaks values and associated prediction values, wherein said data is predictive of depression if a sum of the prediction values of said tree is greater than 1.0.
摘要:
A method for diagnosing Amyotrophic lateral sclerosis includes providing surface-enhanced laser desorption/ionisation mass spectrometric (SELDI-MS) data of a plurality of proteins, said data obtained from a patient and comprising a plurality of peak values, and analysing said peak values with an alternating decision tree comprising a set of tests of said data peaks values and associated prediction values, wherein said data is predictive of depression if a sum of the prediction values of said tree is greater than 1.0.
摘要:
A system and method for mild cognitive impairment (MCI) class discovery using gene expression data are provided. The method comprises: acquiring gene expression data of a patient having MCI; and identifying a putative MCI subtype based on an expression signature in the gene expression data, wherein the putative MCI subtype is identified by using a boosting tree.
摘要:
A method for diagnosing Amyotrophic lateral sclerosis includes providing surface-enhanced laser desorption/ionisation mass spectrometric (SELDI-MS) data of a plurality of proteins, said data obtained from a patient and comprising a plurality of peak values, and analysing said peak values with an alternating decision tree comprising a set of tests of said data peaks values and associated prediction values, wherein said data is predictive of depression if a sum of the prediction values of said tree is greater than 1.0.
摘要:
A system and method for providing personalized health care for Alzheimer's disease (AD) are provided. A method for providing personalized healthcare to a patient suspect of having or having AD, includes: receiving heterogeneous data of the patient; fusing the heterogeneous data by using one of an information fusion or machine learning technique; and providing one of a diagnosis, prognosis or treatment for the patient based on the fused heterogeneous data.
摘要:
A method for navigating digital medical images includes providing a digitized patient medical image of a structure of interest in a patient, using a pre-trained classifier to segment the structure of interest from the image, creating links from the structure of interest to a corresponding structure in an anatomical atlas, receiving a query to view the structure of interest, parsing the query to identify one or more keywords from noun phrases in the query, mapping a keyword to a corresponding structure in the anatomical atlas, wherein the anatomical atlas structure is associated with a link to the corresponding structure in the patient image, and following the link to display said patient structure of interest.
摘要:
A method and system for generation and validation of clinical reports with built-in automated measurement and decision support is provided. XML templates may be used for ensuring report data quality. The template data may include static, dynamic, calculated data, and others. The validation method may be based on formal logical constraint specifications. The constraint descriptions may include data types, cardinality, order, co-occurrence, Boolean logic, read-only data, regular expression patterns, etc. The method can be used to validate collected data on-the-fly based on constraint specifications without human interaction.