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公开(公告)号：US20100274171A1
公开(公告)日：2010-10-28
申请号：US12745454
申请日：2007-12-04
申请人： Luca Caleffi , Giuseppe Franzoni , Francesco Ribolzi , Ranko Sakota , Antonio Rega , Aldo Calimeri , Davide Marchesi
发明人： Luca Caleffi , Giuseppe Franzoni , Francesco Ribolzi , Ranko Sakota , Antonio Rega , Aldo Calimeri , Davide Marchesi
CPC分类号： A61M1/3627 , A61M5/165
摘要： An extracorporeal blood circuit, comprising an expansion chamber for air-blood separation, wherein a filter (38) retains the solid particles in the blood. The filter has a trunco-conical filtering wall with a vertical axis surmounted by a top head (43) provided with upper openings (44) conformed and arranged such as to define a fluid passage which is asymmetrical with respect to the vertical axis. The top head does not retain air bubbles internally thereof, thus preventing a situation in which the air bubbles are directed towards an outlet of the expansion chamber and thus towards the patient. The extracorporeal circuit is used in a dialysis apparatus.
摘要翻译： 一种体外血液回路，包括用于空气 - 血液分离的膨胀室，其中过滤器（38）将固体颗粒保持在血液中。 过滤器具有中空锥形过滤壁，其垂直轴线由顶部设置有顶部开口（43），上部开口（44）构成并布置成限定相对于垂直轴线不对称的流体通道。 顶部的头部内部不保留气泡，从而防止气泡朝向膨胀室的出口并因而导向患者的情况。 体外循环用于透析设备。
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公开(公告)号：US08500672B2
公开(公告)日：2013-08-06
申请号：US12745454
申请日：2007-12-04
申请人： Luca Caleffi , Giuseppe Franzoni , Francesco Ribolzi , Ranko Sakota , Antonio Rega , Aldo Calimeri , Davide Marchesi
发明人： Luca Caleffi , Giuseppe Franzoni , Francesco Ribolzi , Ranko Sakota , Antonio Rega , Aldo Calimeri , Davide Marchesi
IPC分类号： A61M37/00
CPC分类号： A61M1/3627 , A61M5/165
摘要： An extracorporeal blood circuit, comprising an expansion chamber for air-blood separation, wherein a filter (38) retains the solid particles in the blood. The filter has a trunco-conical filtering wall with a vertical axis surmounted by a top head (43) provided with upper openings (44) conformed and arranged such as to define a fluid passage which is asymmetrical with respect to the vertical axis. The top head does not retain air bubbles internally thereof, thus preventing a situation in which the air bubbles are directed towards an outlet of the expansion chamber and thus towards the patient. The extracorporeal circuit is used in a dialysis apparatus.
摘要翻译： 一种体外血液回路，包括用于空气 - 血液分离的膨胀室，其中过滤器（38）将固体颗粒保持在血液中。 过滤器具有中空锥形过滤壁，其垂直轴线由顶部设置有顶部开口（43），上部开口（44）构成并布置成限定相对于垂直轴线不对称的流体通道。 顶部的头部内部不保留气泡，从而防止气泡朝向膨胀室的出口并因而导向患者的情况。 体外循环用于透析设备。
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公开(公告)号：US20100288761A1
公开(公告)日：2010-11-18
申请号：US12447647
申请日：2006-10-30
IPC分类号： B65D47/02
CPC分类号： A61M1/3627 , A61M1/3434 , A61M1/3437 , A61M1/3465
摘要： An extracorporeal blood chamber (12) comprises an expansion reservoir (47) having a first access (48) arranged laterally and a second access (49) arranged on the bottom of the chamber (12). The chamber comprises, integrally with the reservoir, a first conduit terminating in the first access, a second conduit terminating in the first access, and a third conduit terminating in the second access. The extracorporeal blood enters the reservoir through the first conduit and there mixes with an infusion fluid which enters through the second conduit. The resulting mixture exits through the third conduit. The chamber is used in a hemo(dia)filtration apparatus to mix the blood optimally with the replacement fluid.
摘要翻译： 体外血液室（12）包括具有横向布置的第一通路（48）和布置在腔室（12）的底部上的第二通路（49））的膨胀容器（47）。 所述腔室与所述贮存器一体地包括终止于所述第一通道中的第一管道，终止于所述第一通路中的第二管道，以及终止于所述第二通路中的第三管道。 体外血液通过第一导管进入储存器，并且与通过第二导管进入的输注液混合。 所得混合物通过第三导管排出。 该腔室用于血液（dia）过滤装置以最佳地将血液与替换液体混合。
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公开(公告)号：US20100256547A1
公开(公告)日：2010-10-07
申请号：US12517020
申请日：2006-12-01
IPC分类号： A61M5/00
CPC分类号： A61M1/3627 , A61M1/0056
摘要： In a blood transfer chamber, a filter (4) is arranged at an outlet located on a bottom of the chamber. The filter is truncoconical with a vertically-disposed axis. The filter has a plurality of openings (13, 14) for fluid passage, a size of which openings increases gradually in an upwards direction going from bottom to top of the chamber. The filter is used in a venous air-blood separation chamber of a dialysis set. The invention enables a reduction of a risk of hemolysis during treatment as well as a reduction of the risk of formation of air bubble retention in the filter during a priming stage.
摘要翻译： 在血液输送室中，过滤器（4）布置在位于腔室底部的出口处。 过滤器具有垂直设置的轴的截面。 过滤器具有用于流体通道的多个开口（13,14），其开口的尺寸在从底部到顶部的向上方向上逐渐增加。 该过滤器用于透析装置的静脉空气 - 血液分离室。 本发明能够降低治疗期间溶血的风险，并且降低在起泡阶段期间在过滤器中形成气泡保留的风险。
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公开(公告)号：US08647291B2
公开(公告)日：2014-02-11
申请号：US12447647
申请日：2006-10-30
IPC分类号： A61M37/00
CPC分类号： A61M1/3627 , A61M1/3434 , A61M1/3437 , A61M1/3465
摘要： An extracorporeal blood chamber (12) comprises an expansion reservoir (47) having a first access (48) arranged laterally and a second access (49) arranged on the bottom of the chamber (12). The chamber comprises, integrally with the reservoir, a first conduit terminating in the first access, a second conduit terminating in the first access, and a third conduit terminating in the second access. The extracorporeal blood enters the reservoir through the first conduit and there mixes with an infusion fluid which enters through the second conduit. The resulting mixture exits through the third conduit. The chamber is used in a hemo(dia)filtration apparatus to mix the blood optimally with the replacement fluid.
摘要翻译： 体外血液室（12）包括具有横向布置的第一通路（48）和布置在腔室（12）的底部上的第二通路（49））的膨胀容器（47）。 所述腔室与所述贮存器一体地包括终止于所述第一通道中的第一管道，终止于所述第一通路中的第二管道，以及终止于所述第二通路中的第三管道。 体外血液通过第一导管进入储存器，并且与通过第二导管进入的输注液混合。 所得混合物通过第三导管排出。 该腔室用于血液（dia）过滤装置以最佳地将血液与替换液体混合。
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公开(公告)号：US08641657B2
公开(公告)日：2014-02-04
申请号：US12517020
申请日：2006-12-01
CPC分类号： A61M1/3627 , A61M1/0056
摘要： In a blood transfer chamber, a filter (4) is arranged at an outlet located on a bottom of the chamber. The filter is truncoconical with a vertically-disposed axis. The filter has a plurality of openings (13, 14) for fluid passage, a size of which openings increases gradually in an upwards direction going from bottom to top of the chamber. The filter is used in a venous air-blood separation chamber of a dialysis set. The invention enables a reduction of a risk of hemolysis during treatment as well as a reduction of the risk of formation of air bubble retention in the filter during a priming stage.
摘要翻译： 在血液输送室中，过滤器（4）布置在位于腔室底部的出口处。 过滤器具有垂直设置的轴的截面。 过滤器具有用于流体通道的多个开口（13,14），其开口的尺寸在从底部到顶部的向上方向上逐渐增加。 该过滤器用于透析装置的静脉空气 - 血液分离室。 本发明能够降低治疗期间溶血的风险，并且降低在起泡阶段期间在过滤器中形成气泡保留的风险。
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公开(公告)号：US08747342B2
公开(公告)日：2014-06-10
申请号：US12447641
申请日：2006-10-30
申请人： Luca Caleffi , Francesco Ribolzi , Ranko Sakota
发明人： Luca Caleffi , Francesco Ribolzi , Ranko Sakota
IPC分类号： A61M37/00
CPC分类号： A61M1/3638 , A61M1/16 , A61M1/3627 , A61M1/3639 , A61M1/3641 , B01D19/0042
摘要： An air separator (1) comprises a first chamber (2) where blood or other fluid can be received, an inlet and an outlet port associated to the bottom wall (4) and in fluid communication with the first chamber. A first channel (14) extending along the lateral wall of the separator and has a first and a second portion (16 and 18). The channel second portion (18) terminally forms an orifice (15) facing the chamber and extending in an area closer to a top wall (5) of the chamber (2) than to the bottom wall of the same chamber. The orifice faces the top of the separator and has a flow passage cross section greater than that of a first portion (16) of the channel.
摘要翻译： 空气分离器（1）包括可以接收血液或其它流体的第一腔室（2），与底壁（4）相关联并与第一腔室流体连通的入口和出口。 沿分离器的侧壁延伸并具有第一和第二部分（16和18）的第一通道（14）。 通道第二部分（18）终止形成面向腔室的孔口（15），并且在相对于相同腔室的底壁的更靠近腔室（2）的顶壁（5）的区域中延伸。 孔口面对分离器的顶部并且具有大于通道的第一部分（16）的流动通道横截面。
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公开(公告)号：US20100292627A1
公开(公告)日：2010-11-18
申请号：US12447641
申请日：2006-10-30
申请人： Luca Caleffi , Francesco Ribolzi , Ranko Sakota
发明人： Luca Caleffi , Francesco Ribolzi , Ranko Sakota
CPC分类号： A61M1/3638 , A61M1/16 , A61M1/3627 , A61M1/3639 , A61M1/3641 , B01D19/0042
摘要： An air separator (1) comprises a first chamber (2) where blood or other fluid can be received, an inlet and an outlet port associated to the bottom wall (4) and in fluid communication with the first chamber. A first channel (14) extending along the lateral wall of the separator and has a first and a second portion (16 and 18). The channel second portion (18) terminally forms an orifice (15) facing the chamber and extending in an area closer to a top wall (5) of the chamber (2) than to the bottom wall of the same chamber. The orifice faces the top of the separator and has a flow passage cross section greater than that of a first portion (16) of the channel.
摘要翻译： 空气分离器（1）包括可以接收血液或其它流体的第一腔室（2），与底壁（4）相关联并与第一腔室流体连通的入口和出口。 沿分离器的侧壁延伸并具有第一和第二部分（16和18）的第一通道（14）。 通道第二部分（18）终止形成面向腔室的孔口（15），并且在相对于相同腔室的底壁的更靠近腔室（2）的顶壁（5）的区域中延伸。 孔口面对分离器的顶部并且具有大于通道的第一部分（16）的流动通道横截面。
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公开(公告)号：US20100268145A1
公开(公告)日：2010-10-21
申请号：US12447791
申请日：2006-10-30
IPC分类号： A61M1/16 , B01D35/02 , B01D35/30 , B01D61/14 , B01D35/153
CPC分类号： A61M1/342 , A61M1/3434 , A61M1/3465 , A61M1/3621 , A61M2205/12 , A61M2209/082
摘要： A medical fluid circuit comprises a fluid transport unit connected to a source of a medical fluid for infusion into an extracorporeal blood circuit. A support element for the transport line exhibits three engaging projections predisposed for mounting the unit to an external apparatus. A first and a second projection each comprise a first and a second tubular extension (38), while a third projection (37) is distant from an imaginary straight zone which unites the tubular extensions. An ultrafilter (28) for ultrafiltration of the medical fluid is situated in a space comprised between the third projection and the imaginary straight zone. The unit, which is for providing a replacement fluid to a hemo(dia)filtration apparatus, can be easily mounted on the apparatus.
摘要翻译： 医疗流体回路包括连接到用于输注到体外血液回路的医用流体源的流体输送单元。 用于输送线的支撑元件具有倾向于将该单元安装到外部装置的三个啮合突起。 第一和第二突起各自包括第一和第二管状延伸部（38），而第三突出部（37）远离将管状延伸部相结合的假想直线区域。 用于医疗流体超滤的超滤器（28）位于包括在第三突起和假想直线区域之间的空间中。 用于向蒸气（直径）过滤装置提供更换流体的单元可以容易地安装在设备上。
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10.发明授权Degassing device and end-cap assembly for a filter including such a degassing device 有权用于包括这种脱气装置的过滤器的脱气装置和端盖组件公开(公告)号：US08048209B2
公开(公告)日：2011-11-01
申请号：US10595772
申请日：2004-11-02
CPC分类号： A61M1/16 , A61M1/3627 , A61M2205/12 , B01D2313/21
摘要： A degassing device (203) comprises a first chamber (21) having an inlet for a liquid, and a second chamber (22) having an opening (23) closed by a hydrophobic membrane (24) and an outlet (25) for discharging the liquid. The first chamber (21) has a downstream portion that partially extends within the second chamber (22) and communicates therewith by a passageway (28). The second chamber (22) has a downstream portion that extends below the passageway (28) and asymmetrically surrounds the downstream portion of the first chamber (21).
摘要翻译： 脱气装置（203）包括具有用于液体的入口的第一室（21）和具有由疏水膜（24）封闭的开口（23）的第二室（22）和用于将 液体。 第一室（21）具有在第二室（22）内部分地延伸并与通道（28）连通的下游部分。 第二室（22）具有在通道（28）下方延伸并且不对称地包围第一室（21）的下游部分的下游部分。
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