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公开(公告)号：US20130204203A1
公开(公告)日：2013-08-08
申请号：US13576671
申请日：2011-03-16
IPC分类号： A61M5/315
CPC分类号： A61M5/31548 , A61M5/24 , A61M5/3146 , A61M5/31595 , A61M2005/2488 , A61M2005/2492 , A61M2207/00 , Y10T29/49826
摘要： The present invention relates to a drug delivery device for dispensing of a dose of a medicinal product, comprising: a first housing component (12, 52; 62) adapted to receive a cartridge (16) comprising the medicinal product and further comprising a piston (18) slidably arranged therein in an axial direction, a second housing component (14; 54; 64) adapted to receive a dose dispensing mechanism having a piston rod (20) to be operably engaged with the cartridge's piston (18), wherein the first and the second housing components (12, 14; 52, 54; 62, 64) are displaceably arranged in axial direction relative to each other for reducing an axial distance (34) between the piston (18) and the piston rod (20) to a pre-defined degree, and an interlock means (30) adapted to interact with at least one of first and second housing components (12, 14; 52, 54; 62, 64) for mutually locking into position first and second housing components (12, 14; 52, 54; 62, 64).
摘要翻译： 本发明涉及用于分配药物产品剂量的药物递送装置，包括：第一壳体部件（12,52; 62），适于接收包括药物产品的药筒（16），并且还包括活塞（ 18），其沿轴向方向可滑动地布置在其中;第二壳体部件（14; 54; 64），其适于接收剂量分配机构，所述剂量分配机构具有可与所述药筒活塞（18）可操作地接合的活塞杆（20），其中所述第一 并且所述第二壳体部件（12,14; 52,54; 62,64）可相对于彼此沿轴向方向可移位地设置，以便减少所述活塞（18）和所述活塞杆（20）之间的轴向距离（34） 以及互锁装置（30），其适于与第一和第二壳体部件（12,14; 52,54; 62,64）中的至少一个相互作用，以相互锁定到位置第一和第二壳体部件（ 12,14; 52,54; 62,64）。
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公开(公告)号：US20130338600A1
公开(公告)日：2013-12-19
申请号：US14002179
申请日：2012-03-16
申请人： Michael Helmer , Claudia Matthias , Lutz Mueller , Steffen Raab , Peter Nober , Reza Shahbazfar , Benjamin Schäfer , Leo Zeimetz
发明人： Michael Helmer , Claudia Matthias , Lutz Mueller , Steffen Raab , Peter Nober , Reza Shahbazfar , Benjamin Schäfer , Leo Zeimetz
IPC分类号： A61M5/31
CPC分类号： A61M5/31 , A61M5/24 , Y10T29/49826
摘要： A drug delivery device for dispensing of a dose of a medicinal product is presented comprising a first housing component having a receptacle being oval- or elliptically shaped in radial cross section and being adapted to at least partially receive an insert portion of a second housing component being at least partially insertable into said first housing component along an axial direction, wherein the insert portion is oval- or elliptically shaped in radial cross section. The outside dimension or an at least one outside diameter of the insert portion is at least in sections larger than a corresponding inner dimension or an at least one inner diameter of the receptacle and wherein the insert portion and the receptacle are adapted to generate a radially acting mutual clamping of first and second housing components in a pre-fixing assembly configuration.
摘要翻译： 提供了一种用于分配药物产品剂量的药物递送装置，其包括第一壳体部件，所述第一壳体部件具有椭圆形或椭圆形的径向横截面并且适于至少部分地容纳第二壳体部件的插入部分， 至少部分地沿着轴向方向插入所述第一壳体部件中，其中所述插入部分在径向横截面上呈椭圆形或椭圆形。 插入部分的外部尺寸或至少一个外径至少部分地大于插座的对应内部尺寸或至少一个内径，并且其中插入部分和插座适于产生径向作用 将第一和第二壳体部件相互夹紧在预定义组件构造中。
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公开(公告)号：US20120204662A1
公开(公告)日：2012-08-16
申请号：US13379605
申请日：2010-06-28
申请人： Claudia Matthias , Steffen Raab
发明人： Claudia Matthias , Steffen Raab
CPC分类号： A61M5/31551 , A61M5/31575 , A61M5/31585 , Y10T74/18056 , Y10T74/18088
摘要： A drive mechanism (13) for a drug delivery device (1), comprising a housing (2), a transfer member (14), a drive member (16) and a piston rod (18). The transfer member (14) is configured to be rotated about a transfer member rotation axis (20) with respect to the housing (2) for delivering a dose of a drug (5). The drive member (16) is configured to be rotatable around a drive member rotation axis (39) with respect to the housing (2). The drive member (16) is arranged within the transfer member (14). When delivering the dose of the drug (5), the drive member (16) rotates about the drive member rotation axis (39). When delivering the dose of the drug (5), the drive member (16) and the transfer member (14) interact mechanically to convert rotation of the transfer member (14) about the transfer member rotation axis (20) into rotation of the drive member (16) about the drive member rotation axis (39), wherein rotation of the drive member (16) about the drive member rotation axis (39) is converted into translatory movement of the piston rod (18) with respect to the housing (2).
摘要翻译： 一种用于药物输送装置（1）的驱动机构（13），包括壳体（2），转移构件（14），驱动构件（16）和活塞杆（18）。 传送构件（14）构造成相对于壳体（2）围绕传送构件旋转轴线（20）旋转，用于递送药物（5）的剂量。 驱动构件（16）构造成能够相对于壳体（2）围绕驱动构件旋转轴线（39）旋转。 驱动构件（16）布置在转移构件（14）内。 当递送药物（5）的剂量时，驱动构件（16）围绕驱动构件旋转轴线（39）旋转。 当输送药物（5）的剂量时，驱动构件（16）和转移构件（14）机械地相互作用以将转印构件（14）围绕传送构件旋转轴线（20）的旋转转换成驱动器的旋转 构件（16）围绕驱动构件旋转轴线（39）旋转，其中驱动构件（16）围绕驱动构件旋转轴线（39）的旋转被转换成活塞杆（18）相对于壳体的平移运动 2）。
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公开(公告)号：US09022992B2
公开(公告)日：2015-05-05
申请号：US13512180
申请日：2010-12-02
申请人： Michael Helmer , Steffen Raab
发明人： Michael Helmer , Steffen Raab
CPC分类号： A61M5/31555 , A61M5/24 , A61M5/3146 , A61M5/3156 , A61M5/3158 , A61M5/31593 , A61M2005/31506
摘要： A drug delivery device comprises a housing and a piston rod arranged in the housing. The piston rod is adapted to be moved along an axial direction to dispense a fluid. A drive member arranged in the housing is operatively coupled to the piston rod and adapted to set up a dose of fluid for dispense in response to a first movement. The drive member is also adapted to move the piston rod to dispense the dose in response to a second movement. The drug delivery device also comprises a pre-dispensing drive member operatively coupled to the drive member and the housing and adapted to move at least the drive member by a pre-dispensing distance between its first and second movement.
摘要翻译： 药物输送装置包括设置在壳体中的壳体和活塞杆。 活塞杆适于沿轴向移动以分配流体。 布置在壳体中的驱动构件可操作地联接到活塞杆并且适于设置响应于第一运动而分配的剂量的流体。 驱动构件还适于移动活塞杆以响应于第二运动而分配剂量。 药物递送装置还包括预分配驱动构件，其可操作地联接到驱动构件和壳体并且适于在其第一和第二运动之间通过预分配距离至少移动驱动构件。
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公开(公告)号：US20130041325A1
公开(公告)日：2013-02-14
申请号：US13512180
申请日：2010-12-02
申请人： Michael Helmer , Steffen Raab
发明人： Michael Helmer , Steffen Raab
IPC分类号： A61M5/315
CPC分类号： A61M5/31555 , A61M5/24 , A61M5/3146 , A61M5/3156 , A61M5/3158 , A61M5/31593 , A61M2005/31506
摘要： A drug delivery device comprises a housing and a piston rod arranged in the housing. The piston rod is adapted to be moved along an axial direction to dispense a fluid. A drive member arranged in the housing is operatively coupled to the piston rod and adapted to set up a dose of fluid for dispense in response to a first movement. The drive member is also adapted to move the piston rod to dispense the dose in response to a second movement. The drug delivery device also comprises a pre-dispensing drive member operatively coupled to the drive member and the housing and adapted to move at least the drive member by a pre-dispensing distance between its first and second movement.
摘要翻译： 药物输送装置包括设置在壳体中的壳体和活塞杆。 活塞杆适于沿轴向移动以分配流体。 布置在壳体中的驱动构件可操作地联接到活塞杆并且适于设置响应于第一运动而分配的剂量的流体。 驱动构件还适于移动活塞杆以响应于第二运动而分配剂量。 药物递送装置还包括预分配驱动构件，其可操作地联接到驱动构件和壳体并且适于在其第一和第二运动之间通过预分配距离至少移动驱动构件。
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公开(公告)号：US09808585B2
公开(公告)日：2017-11-07
申请号：US14002177
申请日：2012-03-15
申请人： Stefan Wendland , Steffen Raab , Peggy Rabe
发明人： Stefan Wendland , Steffen Raab , Peggy Rabe
CPC分类号： A61M5/5086 , A61M5/24 , A61M5/50
摘要： A drug delivery device for administering a dose of a medicament by way of injection is disclosed, the device including a housing to receive a cartridge at least partially filled with a medicament and being sealed with a piston slidably disposed therein, a drive mechanism having a piston rod to be displaced in a distal direction to operably engage with the piston of the cartridge, a dose button operably engaged with the drive mechanism for at least one of preparing or initiating a dose dispensing action of the drive mechanism, and a protective member adapted to impede actuation of the dose button, wherein the protective member is releasably connected to the housing via a breakable seal.
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公开(公告)号：US09802004B2
公开(公告)日：2017-10-31
申请号：US13393331
申请日：2010-09-03
申请人： Steffen Raab , Sandra Arnhold
发明人： Steffen Raab , Sandra Arnhold
CPC分类号： A61M5/31593 , A61M5/24 , A61M5/31551 , A61M5/31583 , A61M5/31585
摘要： A piston rod is arranged in a body and provided with a helical element and an axial element. A guide element, which is arranged in the body and fixed relatively to the body, is coupled to the helical element to guide a helical movement of the piston rod and coupled to the axial element to guide an axial movement of the piston rod. The axial movement allows a priming of the device preceding the helical movement of the piston rod.
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公开(公告)号：US09737666B2
公开(公告)日：2017-08-22
申请号：US13504296
申请日：2010-11-01
申请人： Philippe Nzike , Steffen Raab , Uwe Dasbach , Uwe Boeser , Ulrich Bruggemann , Brice Ulrich Tchouadje , Kevin Igor Youmbi Ngatchou
发明人： Philippe Nzike , Steffen Raab , Uwe Dasbach , Uwe Boeser , Ulrich Bruggemann
CPC分类号： A61M5/31535 , A61M5/24 , A61M5/31555 , A61M5/31556 , A61M5/31585 , A61M2005/2407 , A61M2205/581 , A61M2205/582
摘要： An assembly for a drug delivery device is disclosed. An example assembly includes a housing, a rotation member, a drive member, and at least one correction member. The rotation member is adapted to be rotated with respect to the housing in a first rotational direction for delivering a dose of a drug. The drive member is coupleable to the rotation member for delivering the dose. In a delivery mode, the drive member and the rotation member are coupled such that the drive member follows rotational movement of the rotation member in the first rotational direction due to mechanical interaction of the rotation member and the drive member. In a correction mode, the rotation member and the drive member are decoupled such that the rotation member is rotatable in the first rotational direction with respect to the drive member.
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公开(公告)号：US09623185B2
公开(公告)日：2017-04-18
申请号：US13701969
申请日：2011-06-09
CPC分类号： A61M5/31511 , A61M5/24 , A61M5/31543 , A61M5/3155 , A61M5/31551 , A61M5/31553 , A61M5/31555 , A61M5/3158 , A61M5/31583 , A61M5/31585
摘要： An assembly for a drug delivery device is provided, comprising a housing, a rotation member adapted and arranged to be rotated in a first and in a second rotational direction with respect to the housing in an operational mode of the assembly, a drive member which is configured to mechanically cooperate with the rotation member such that the drive member follows rotation of the rotation member when the rotation member is rotated in the second rotational direction and such that the rotation member rotates with respect to the drive member when the rotation member is rotated in the first rotational direction, and a piston rod. The assembly further comprises at least one biasing member which is adapted and arranged to provide a force tending to bring the rotation member and the drive member out of mechanical cooperation in the operational mode. The assembly is switchable from the operational mode into a reset mode. For switching from the operational mode into the reset mode, the biasing member is configured to drive a relative axial movement between the drive member and the rotation member such that the rotation member and the drive member are brought out of mechanical cooperation. Furthermore, a drug delivery device is provided.
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公开(公告)号：US09381305B2
公开(公告)日：2016-07-05
申请号：US13258162
申请日：2010-03-31
申请人： Michael Harms , Steffen Raab , Udo Stauder
发明人： Michael Harms , Steffen Raab , Udo Stauder
CPC分类号： A61M5/31525 , A61M5/315 , A61M5/31543 , A61M2005/3115
摘要： The medical device comprises a wave spring or wave washer in a mechanism to engage or disengage a first element and a second element. The invention also discloses the use of a multiple wave spring or wave washer comprising at least two waved spring layers in a medical device.
摘要翻译： 该医疗装置包括波形弹簧或波形垫圈，其在与第一元件和第二元件接合或分离的机构中。 本发明还公开了在医疗装置中使用包括至少两个波形弹簧层的多波形弹簧或波形垫圈。
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