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公开(公告)号：US20130211342A1
公开(公告)日：2013-08-15
申请号：US13701969
申请日：2011-06-09
IPC分类号： A61M5/315
CPC分类号： A61M5/31511 , A61M5/24 , A61M5/31543 , A61M5/3155 , A61M5/31551 , A61M5/31553 , A61M5/31555 , A61M5/3158 , A61M5/31583 , A61M5/31585
摘要： An assembly for a drug delivery device is provided, comprising a housing, a rotation member adapted and arranged to be rotated in a first and in a second rotational direction with respect to the housing in an operational mode of the assembly, a drive member which is configured to mechanically cooperate with the rotation member such that the drive member follows rotation of the rotation member when the rotation member is rotated in the second rotational direction and such that the rotation member rotates with respect to the drive member when the rotation member is rotated in the first rotational direction, and a piston rod. The assembly further comprises at least one biasing member which is adapted and arranged to provide a force tending to bring the rotation member and the drive member out of mechanical cooperation in the operational mode. The assembly is switchable from the operational mode into a reset mode. For switching from the operational mode into the reset mode, the biasing member is configured to drive a relative axial movement between the drive member and the rotation member such that the rotation member and the drive member are brought out of mechanical cooperation. Furthermore, a drug delivery device is provided.
摘要翻译： 提供了一种用于药物输送装置的组件，包括壳体，旋转构件，其适于并布置成在组件的操作模式下相对于壳体在第一和第二旋转方向上旋转;驱动构件， 被构造成与所述旋转构件机械配合，使得当所述旋转构件沿所述第二旋转方向旋转时，所述驱动构件沿着所述旋转构件的旋转，并且使得当所述旋转构件旋转时所述旋转构件相对于所述驱动构件旋转 第一旋转方向和活塞杆。 该组件还包括至少一个偏置构件，该至少一个偏置构件适于并布置成提供趋向于使操作模式中的旋转构件和驱动构件脱离机械协作的力。 组件可以从操作模式切换到复位模式。 为了从操作模式切换到复位模式，偏置构件被构造成驱动驱动构件和旋转构件之间的相对轴向运动，使得旋转构件和驱动构件脱离机械协作。 此外，提供了药物输送装置。
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公开(公告)号：US09623185B2
公开(公告)日：2017-04-18
申请号：US13701969
申请日：2011-06-09
CPC分类号： A61M5/31511 , A61M5/24 , A61M5/31543 , A61M5/3155 , A61M5/31551 , A61M5/31553 , A61M5/31555 , A61M5/3158 , A61M5/31583 , A61M5/31585
摘要： An assembly for a drug delivery device is provided, comprising a housing, a rotation member adapted and arranged to be rotated in a first and in a second rotational direction with respect to the housing in an operational mode of the assembly, a drive member which is configured to mechanically cooperate with the rotation member such that the drive member follows rotation of the rotation member when the rotation member is rotated in the second rotational direction and such that the rotation member rotates with respect to the drive member when the rotation member is rotated in the first rotational direction, and a piston rod. The assembly further comprises at least one biasing member which is adapted and arranged to provide a force tending to bring the rotation member and the drive member out of mechanical cooperation in the operational mode. The assembly is switchable from the operational mode into a reset mode. For switching from the operational mode into the reset mode, the biasing member is configured to drive a relative axial movement between the drive member and the rotation member such that the rotation member and the drive member are brought out of mechanical cooperation. Furthermore, a drug delivery device is provided.
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公开(公告)号：US20130190697A1
公开(公告)日：2013-07-25
申请号：US13702808
申请日：2011-06-09
IPC分类号： A61M5/315
CPC分类号： A61M5/31543 , A61M5/24 , A61M5/3155 , A61M5/31551 , A61M5/31553 , A61M5/31555 , A61M5/3158 , A61M5/31583 , A61M5/31585
摘要： A drive mechanism for a drug delivery device which can be switched between a normal operation state and a reset state comprises of a housing having a proximal end and a distal end, a rotation member which is adapted to rotate in a first direction and in a second direction with respect to the housing, a drive member, wherein in the normal operation state the rotation member is coupled with the drive member so that the drive member follows rotational movement of the rotation member in the second direction, a piston rod, wherein in the normal operation state the piston rod is displaced in a distal direction with respect to the housing when the drive member rotates in the second direction with respect to the housing, a stop member, wherein in the normal operation state the stop member is coupled with the drive member so that the stop member prevents rotational movement of the drive member with respect to the housing in the first direction, and a separation member for switching the operation state, the separation member being adapted to move the stop member and the drive member in the distal direction with respect to the housing when the normal operation state is switched to the reset state, thereby decoupling the stop member and the drive member and decoupling the drive member and the rotation member.
摘要翻译： 用于可在正常操作状态和复位状态之间切换的药物输送装置的驱动机构包括具有近端和远端的壳体，适于沿第一方向旋转的旋转构件 方向相对于壳体，驱动构件，其中在正常操作状态下，旋转构件与驱动构件联接，使得驱动构件沿第二方向旋转构件的旋转运动，活塞杆，其中在 当驱动构件相对于壳体沿第二方向旋转时，活塞杆相对于壳体在远端方向上移位，其中在正常操作状态下，止动构件与驱动器联接 使得止动构件防止驱动构件相对于壳体沿第一方向的旋转运动，以及用于切换操作的分离构件 n状态，当正常操作状态切换到复位状态时，分离构件适于在远端方向上相对于壳体移动止动构件和驱动构件，从而使止动构件和驱动构件分离， 驱动构件和旋转构件。
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公开(公告)号：US09498576B2
公开(公告)日：2016-11-22
申请号：US13702808
申请日：2011-06-09
CPC分类号： A61M5/31543 , A61M5/24 , A61M5/3155 , A61M5/31551 , A61M5/31553 , A61M5/31555 , A61M5/3158 , A61M5/31583 , A61M5/31585
摘要： A drive mechanism for a drug delivery device which can be switched between a normal operation state and a reset state comprises of a housing having a proximal end and a distal end, a rotation member which is adapted to rotate in a first direction and in a second direction with respect to the housing, a drive member, wherein in the normal operation state the rotation member is coupled with the drive member so that the drive member follows rotational movement of the rotation member in the second direction, a piston rod, wherein in the normal operation state the piston rod is displaced in a distal direction with respect to the housing when the drive member rotates in the second direction with respect to the housing, a stop member, wherein in the normal operation state the stop member is coupled with the drive member so that the stop member prevents rotational movement of the drive member with respect to the housing in the first direction, and a separation member for switching the operation state, the separation member being adapted to move the stop member and the drive member in the distal direction with respect to the housing when the normal operation state is switched to the reset state, thereby decoupling the stop member and the drive member and decoupling the drive member and the rotation member.
摘要翻译： 用于可在正常操作状态和复位状态之间切换的药物输送装置的驱动机构包括具有近端和远端的壳体，适于沿第一方向旋转的旋转构件 方向相对于壳体，驱动构件，其中在正常操作状态下，旋转构件与驱动构件联接，使得驱动构件沿第二方向旋转构件的旋转运动，活塞杆，其中在 当驱动构件相对于壳体沿第二方向旋转时，活塞杆相对于壳体在远端方向上移位，其中在正常操作状态下，止动构件与驱动器联接 使得止动构件防止驱动构件相对于壳体沿第一方向的旋转运动，以及用于切换操作的分离构件 n状态，当正常操作状态切换到复位状态时，分离构件适于在远端方向上相对于壳体移动止动构件和驱动构件，从而使止动构件和驱动构件分离， 驱动构件和旋转构件。
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公开(公告)号：US09808585B2
公开(公告)日：2017-11-07
申请号：US14002177
申请日：2012-03-15
申请人： Stefan Wendland , Steffen Raab , Peggy Rabe
发明人： Stefan Wendland , Steffen Raab , Peggy Rabe
CPC分类号： A61M5/5086 , A61M5/24 , A61M5/50
摘要： A drug delivery device for administering a dose of a medicament by way of injection is disclosed, the device including a housing to receive a cartridge at least partially filled with a medicament and being sealed with a piston slidably disposed therein, a drive mechanism having a piston rod to be displaced in a distal direction to operably engage with the piston of the cartridge, a dose button operably engaged with the drive mechanism for at least one of preparing or initiating a dose dispensing action of the drive mechanism, and a protective member adapted to impede actuation of the dose button, wherein the protective member is releasably connected to the housing via a breakable seal.
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公开(公告)号：US09802004B2
公开(公告)日：2017-10-31
申请号：US13393331
申请日：2010-09-03
申请人： Steffen Raab , Sandra Arnhold
发明人： Steffen Raab , Sandra Arnhold
CPC分类号： A61M5/31593 , A61M5/24 , A61M5/31551 , A61M5/31583 , A61M5/31585
摘要： A piston rod is arranged in a body and provided with a helical element and an axial element. A guide element, which is arranged in the body and fixed relatively to the body, is coupled to the helical element to guide a helical movement of the piston rod and coupled to the axial element to guide an axial movement of the piston rod. The axial movement allows a priming of the device preceding the helical movement of the piston rod.
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公开(公告)号：US09737666B2
公开(公告)日：2017-08-22
申请号：US13504296
申请日：2010-11-01
申请人： Philippe Nzike , Steffen Raab , Uwe Dasbach , Uwe Boeser , Ulrich Bruggemann , Brice Ulrich Tchouadje , Kevin Igor Youmbi Ngatchou
发明人： Philippe Nzike , Steffen Raab , Uwe Dasbach , Uwe Boeser , Ulrich Bruggemann
CPC分类号： A61M5/31535 , A61M5/24 , A61M5/31555 , A61M5/31556 , A61M5/31585 , A61M2005/2407 , A61M2205/581 , A61M2205/582
摘要： An assembly for a drug delivery device is disclosed. An example assembly includes a housing, a rotation member, a drive member, and at least one correction member. The rotation member is adapted to be rotated with respect to the housing in a first rotational direction for delivering a dose of a drug. The drive member is coupleable to the rotation member for delivering the dose. In a delivery mode, the drive member and the rotation member are coupled such that the drive member follows rotational movement of the rotation member in the first rotational direction due to mechanical interaction of the rotation member and the drive member. In a correction mode, the rotation member and the drive member are decoupled such that the rotation member is rotatable in the first rotational direction with respect to the drive member.
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公开(公告)号：US09381305B2
公开(公告)日：2016-07-05
申请号：US13258162
申请日：2010-03-31
申请人： Michael Harms , Steffen Raab , Udo Stauder
发明人： Michael Harms , Steffen Raab , Udo Stauder
CPC分类号： A61M5/31525 , A61M5/315 , A61M5/31543 , A61M2005/3115
摘要： The medical device comprises a wave spring or wave washer in a mechanism to engage or disengage a first element and a second element. The invention also discloses the use of a multiple wave spring or wave washer comprising at least two waved spring layers in a medical device.
摘要翻译： 该医疗装置包括波形弹簧或波形垫圈，其在与第一元件和第二元件接合或分离的机构中。 本发明还公开了在医疗装置中使用包括至少两个波形弹簧层的多波形弹簧或波形垫圈。
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公开(公告)号：US09078973B2
公开(公告)日：2015-07-14
申请号：US13258151
申请日：2010-03-31
申请人： Michael Harms , Steffen Raab , Uwe Dasbach , Udo Stauder
发明人： Michael Harms , Steffen Raab , Uwe Dasbach , Udo Stauder
CPC分类号： A61M5/3129 , A61M5/3135 , A61M5/321 , A61M2005/3139
摘要： A drug delivery device comprises an outer housing rollable around a rotation axis and at least one stop member. The stop member protrudes radially from the outer housing of the drug delivery device and is configured to prevent rolling movement of the drug delivery device along a predetermined surface. The outer housing comprises a main housing and a dose member. The dose member is movable with respect to the main housing when setting and/or delivering a dose of a drug. The stop member comprises a first part and a second part, wherein the first part is arranged on the main housing and the second part is arranged on the dose member.
摘要翻译： 药物输送装置包括围绕旋转轴线可滚动的外壳体和至少一个止动件。 止动构件从药物输送装置的外壳径向地突出并且构造成防止药物输送装置沿着预定表面的滚动运动。 外壳包括主壳体和剂量构件。 当设置和/或递送药物的剂量时，剂量构件可相对于主壳体移动。 止挡构件包括第一部分和第二部分，其中第一部分布置在主壳体上，并且第二部分布置在剂量构件上。
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公开(公告)号：US09022992B2
公开(公告)日：2015-05-05
申请号：US13512180
申请日：2010-12-02
申请人： Michael Helmer , Steffen Raab
发明人： Michael Helmer , Steffen Raab
CPC分类号： A61M5/31555 , A61M5/24 , A61M5/3146 , A61M5/3156 , A61M5/3158 , A61M5/31593 , A61M2005/31506
摘要： A drug delivery device comprises a housing and a piston rod arranged in the housing. The piston rod is adapted to be moved along an axial direction to dispense a fluid. A drive member arranged in the housing is operatively coupled to the piston rod and adapted to set up a dose of fluid for dispense in response to a first movement. The drive member is also adapted to move the piston rod to dispense the dose in response to a second movement. The drug delivery device also comprises a pre-dispensing drive member operatively coupled to the drive member and the housing and adapted to move at least the drive member by a pre-dispensing distance between its first and second movement.
摘要翻译： 药物输送装置包括设置在壳体中的壳体和活塞杆。 活塞杆适于沿轴向移动以分配流体。 布置在壳体中的驱动构件可操作地联接到活塞杆并且适于设置响应于第一运动而分配的剂量的流体。 驱动构件还适于移动活塞杆以响应于第二运动而分配剂量。 药物递送装置还包括预分配驱动构件，其可操作地联接到驱动构件和壳体并且适于在其第一和第二运动之间通过预分配距离至少移动驱动构件。
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