公开(公告)号：US11085916B2

公开(公告)日：2021-08-10

申请号：US16085755

申请日：2017-07-18

Applicant: MANDOM CORPORATION ,  OSAKA UNIVERSITY

Inventor： Kie Nakashima ,  Ryuichiro Kurata ,  Fumitaka Fujita ,  Kiyotoshi Sekiguchi ,  Atsushi Tanemura ,  Hiroyuki Murota ,  Ichiro Katayama

IPC: G01N33/50 ,  A61B5/00 ,  A61K38/18

Abstract: A method for observing the dynamics of sweat glands and a method for evaluating a substance of interest, which are useful for development of a preparation for external application, such as a cosmetic. In each of the methods, an observation sample is used, which is prepared by staining all sweat glands, which are isolated alive, with a staining reagent, and then holding the all sweat glands on a support using at least one material selected from the group consisting of collagen, agarose, basement membrane matrix, poly-D-lysine and a membrane.

公开(公告)号：US20190049429A1

公开(公告)日：2019-02-14

申请号：US16085755

申请日：2017-07-18

Applicant: MANDOM CORPORATION ,  OSAKA UNIVERSITY

Inventor： Kie Nakashima ,  Ryuichiro Kurata ,  Fumitaka Fujita ,  Kiyotoshi Sekiguchi ,  Atsushi Tanemura ,  Hiroyuki Murota ,  Ichiro Katayama

IPC: G01N33/50 ,  A61B5/00

Abstract: A method for observing the dynamics of sweat glands and a method for evaluating a substance of interest, which are useful for development of a preparation for external application, such as a cosmetic. In each of the methods, an observation sample is used, which is prepared by staining all sweat glands, which are isolated alive, with a staining reagent, and then holding the all sweat glands on a support using at least one material selected from the group consisting of collagen, agarose, basement membrane matrix, poly-D-lysine and a membrane.