专利检索 ap:("MATINAS BIOPHARMA NANOTECHNOLOGIES, INC.") AND inv:"Doug F. Kling" 第 1 页

1.

发明授权
Encholeated antifungal compounds for central nervous system delivery and treatment of Cryptococcus infections 有权

公开(公告)号：US11123295B2

公开(公告)日：2021-09-21

申请号：US16312047

申请日：2017-07-12

申请人： MATINAS BIOPHARMA NANOTECHNOLOGIES, INC.

发明人： Raphael J. Mannino , Ruying Lu , Doug F. Kling

IPC分类号： A61K9/127 , A61P31/10 , A61K9/00 , A61K31/7048 , A61K47/24 , A61K31/513

摘要： The present application is directed to a cochleate composition including one or more cochleates and at least two antifungal compounds selected from amphotericin B, 5-flucytosine, fluconazole, ketoconazole, ravuconazole, albaconazole, itraconazole, posaconazole, isavuconazole and/or voriconazole. Methods of using the antifungal cochleate formulations are also disclosed.

2.

发明申请
ENCHOLEATED ANTIFUNGAL COMPOUNDS FOR CENTRAL NERVOUS SYSTEM DELIVERY AND TREATMENT OF CRYPTOCOCCUS INFECTIONS 有权

公开(公告)号：US20210393526A1

公开(公告)日：2021-12-23

申请号：US17463021

申请日：2021-08-31

申请人： MATINAS BIOPHARMA NANOTECHNOLOGIES, INC.

发明人： Raphael J. Mannino , Ruying Lu , Doug F. Kling

IPC分类号： A61K9/127 , A61P31/10 , A61K9/00 , A61K31/7048 , A61K47/24

摘要： The present application is directed to a cochleate composition including one or more cochleates and at least two anti-fungal compounds selected from amphotericin B, 5-flucytosine, fluconazole, ketoconazole, ravuconazole, albaconazole, itraconazole, oposaconazole, isavuconazole and/or voriconazole. Methods of using the antifungal cochleate formulations are also disclosed.