公开(公告)号：US11136315B2

公开(公告)日：2021-10-05

申请号：US16960468

申请日：2019-01-11

申请人： MEDSHINE DISCOVERY INC.

发明人： Bin Chen ,  Xiawei Wei ,  Xuefeng Sun ,  Lei Zhang ,  Zhaoying Xu ,  Wenli Li ,  Peng Zhang ,  Feng Gao ,  Yunfu Luo ,  Jian Li ,  Shuhui Chen

IPC分类号： C07D405/12 ,  A61P11/00 ,  C07D211/54 ,  C07D215/38 ,  C07D277/64 ,  C07D307/81 ,  C07D333/52 ,  C07D409/12 ,  C07D413/12 ,  C07D417/12 ,  C07D491/048

摘要： A compound as a CXCR2 antagonist and an application thereof in preparing a drug as a CXCR2 antagonist. In particular, the present invention relates to a compound represented by formula (II) or an isomer or pharmaceutically acceptable salt thereof.