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公开(公告)号:US20220370095A1
公开(公告)日:2022-11-24
申请号:US17661669
申请日:2022-05-02
发明人: Aram Jamous , Tomas K. Kelly , Michael James Donegan , Alan Ryan , Eoghan Jennings , Eoin J. Walsh , Aran Murray
IPC分类号: A61B17/3207
摘要: The present disclosure provides a tissue-removing catheter that includes an elongate body, a tissue-removing element, and an inner liner. The elongate body has proximal and distal end portions spaced apart from one another along an axis and is sized and shaped to be received in a body lumen. The tissue-removing element rotates by the elongate body to remove tissue. The inner liner is received within the elongate body, defines a guidewire lumen, and isolates an interior of the guidewire lumen from the elongate body and tissue-removing element, preventing torsional force from transferring from the elongate body and tissue-removing element to the interior of the guidewire lumen. The inner liner includes a distal end margin that may have a construction different from a construction of a second portion of the inner liner proximal of the distal end margin. The distal end margin may be more flexible than the second portion.
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公开(公告)号:US20220265295A1
公开(公告)日:2022-08-25
申请号:US17653253
申请日:2022-03-02
发明人: Gerry Oliver McCaffrey , Grainne Teresa Carroll , Risa Tom Egerter , Aran Murray , Jonathan Ashley Cope , Peter Glynn , Christopher W. Storment , Jack Wallis
IPC分类号: A61B17/22
摘要: A catheter assembly includes a catheter comprising a flexible elongated member including a distal portion that includes a tubular body defining an inner lumen and a plurality of body apertures that extend through a sidewall of the tubular body into the inner lumen, and a plurality of primary electrodes positioned along the tubular body. The catheter assembly includes a wire defining at least one secondary electrode, the wire being configured to be slidably moved through the inner lumen of the tubular body, where the wire and the plurality of primary electrodes are configured to electrically couple to an energy source that delivers an electrical pulse to a fluid in contact with the plurality of primary electrodes and the at least one secondary electrode to cause the fluid to undergo cavitation to generate a pressure pulse wave within the fluid.
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公开(公告)号:US11266817B2
公开(公告)日:2022-03-08
申请号:US16661517
申请日:2019-10-23
发明人: Jonathan Ashley Cope , Risa Tom Egerter , Gerry Oliver McCaffrey , Peter Glynn , Jack Wallis , Aran Murray
摘要: In some examples, a catheter includes an elongated member including at least one balloon connected to the elongated member, the at least one balloon being configured to inflate to an expanded state. In the expanded state, the at least one balloon forms at least a portion of a cavity with a wall of a vessel of the patient. The catheter including at least one electrode carried by the elongated member and having at least one surface exposed to the cavity formed by the at least one balloon. The electrode is configured to connect to an energy source that is configured to deliver, via the electrode, an electrical signal to a fluid contained in the cavity and in contact with the electrode to cause the fluid to undergo cavitation to generate a pressure pulse wave within the fluid.
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公开(公告)号:US11931261B2
公开(公告)日:2024-03-19
申请号:US17674341
申请日:2022-02-17
发明人: Niall Duffy , David Farascioni , Adam Fitzgerald , Nathan Knutson , Ana Menk , Aran Murray , Jay Rassat
IPC分类号: A61F2/24
CPC分类号: A61F2/2454 , A61F2/2466 , A61F2210/0014 , A61F2220/0008 , A61F2220/0091 , A61F2250/001
摘要: A prolapse prevention device formed by a continuous wire-like structure having a first end and a second end disconnected from each other. The continuous wire-like structure of the prolapse prevention device is substantially straight in a delivery configuration. The prolapse prevention device in a deployed configuration includes a centering ring of the continuous wire-like structure configured to seat adjacent to and upstream of an annulus of a heart valve in situ, a vertical support of the continuous wire-like structure which extends from the centering ring and includes an apex configured to seat against a roof of an atrium in situ, and a leaflet backstop of the continuous wire-like structure extending radially inward from the centering ring and configured to contact at least at least a first leaflet of the heart valve in situ to exert a pressure in a downstream direction on the first leaflet to prevent the first leaflet from prolapsing into the atrium.
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公开(公告)号:US20220313308A1
公开(公告)日:2022-10-06
申请号:US17653069
申请日:2022-03-01
发明人: Alan Ryan , Eoghan Jennings , Aran Murray
IPC分类号: A61B17/3207
摘要: The present disclosure provides a tissue-removing catheter that includes an elongate body with proximal and distal end portions, a tissue-removing element, an inner liner, and a coupling assembly. The tissue-removing element removes tissue by rotation from the elongate body. The inner liner defines a guidewire lumen received within the elongate body and is coupled to the tissue-removing element at its distal end portion. The coupling assembly includes a bushing attached to the distal end portion of the inner liner and a bearing disposed around the bushing with an exterior surface of the bushing contacting an interior surface of the bearing along less than 50% of an internal surface area of the interior surface of the bearing. At least one of the exterior surface of the bushing and the interior surface of the bearing may define a non-uniform dimension extending along a length of one of the bushing and bearing.
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公开(公告)号:US11707289B2
公开(公告)日:2023-07-25
申请号:US17653253
申请日:2022-03-02
发明人: Gerry Oliver McCaffrey , Grainne Teresa Carroll , Risa Tom Egerter , Aran Murray , Jonathan Ashley Cope , Peter Glynn , Christopher W. Storment , Jack Wallis
CPC分类号: A61B17/22022 , A61B2017/0019 , A61B2017/00411 , A61B2017/22008 , A61B2017/22038 , A61B2017/22074 , A61M25/007 , A61M25/0074
摘要: A catheter assembly includes a catheter comprising a flexible elongated member including a distal portion that includes a tubular body defining an inner lumen and a plurality of body apertures that extend through a sidewall of the tubular body into the inner lumen, and a plurality of primary electrodes positioned along the tubular body. The catheter assembly includes a wire defining at least one secondary electrode, the wire being configured to be slidably moved through the inner lumen of the tubular body, where the wire and the plurality of primary electrodes are configured to electrically couple to an energy source that delivers an electrical pulse to a fluid in contact with the plurality of primary electrodes and the at least one secondary electrode to cause the fluid to undergo cavitation to generate a pressure pulse wave within the fluid.
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公开(公告)号:US20230064262A1
公开(公告)日:2023-03-02
申请号:US17812580
申请日:2022-07-14
发明人: Aran Murray , Eoin J. Walsh , Thomas P. Hayden , Martin B. Patten
IPC分类号: A61B17/3207
摘要: A tissue-removing catheter includes a drive assembly. The drive assembly includes a gear rotatable about an axis, a gear extension coupled to the gear and extending axially outward from the gear, and a lock received in and coupled to the gear extension. The gear extension is rotatably driven by the gear, and the lock is rotatably driven by the gear extension. An elongate drive member is received in and coupled to the lock. The drive member is driven by the lock, whereby rotation of the gear imparts rotation to the drive coil.
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公开(公告)号:US20220313307A1
公开(公告)日:2022-10-06
申请号:US17654230
申请日:2022-03-09
发明人: Rebecca Marie Helebert , Thomas P. Hayden , Aram Jamous , Conor McMullen , Tomas K. Kelly , Michael James Donegan , Eoin J. Walsh , Aran Murray
IPC分类号: A61B17/3207
摘要: A tissue-removing catheter for removing tissue in a body lumen includes an elongate body having an axis. A handle is mounted to a proximal end portion of the elongate body. A tissue-removing element is mounted on a distal end portion of the elongate body. An inner liner is received within the elongate body and defines a guidewire lumen. An advancer is mounted on the handle and is movable relative to the housing. The inner liner is coupled to the advancer at a proximal end portion of the inner liner such that movement of the advancer causes a corresponding movement of the inner liner to exert a push force on the tissue-removing element to advance the tissue-removing element and a pull force on the tissue-removing element to retract the tissue-removing element for moving the tissue-removing element relative to the handle.
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公开(公告)号:US11285003B2
公开(公告)日:2022-03-29
申请号:US16352976
申请日:2019-03-14
发明人: Niall Duffy , David Farascioni , Adam Fitzgerald , Nathan Knutson , Ana Menk , Aran Murray , Jay Rassat
IPC分类号: A61F2/24
摘要: A prolapse prevention device formed by a continuous wire-like structure having a first end and a second end disconnected from each other. The continuous wire-like structure of the prolapse prevention device is substantially straight in a delivery configuration. The prolapse prevention device in a deployed configuration includes a centering ring of the continuous wire-like structure configured to seat adjacent to and upstream of an annulus of a heart valve in situ, a vertical support of the continuous wire-like structure which extends from the centering ring and includes an apex configured to seat against a roof of an atrium in situ, and a leaflet backstop of the continuous wire-like structure extending radially inward from the centering ring and configured to contact at least at least a first leaflet of the heart valve in situ to exert a pressure in a downstream direction on the first leaflet to prevent the first leaflet from prolapsing into the atrium.
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公开(公告)号:US11826092B2
公开(公告)日:2023-11-28
申请号:US16661736
申请日:2019-10-23
CPC分类号: A61B18/1492 , A61M25/09 , A61B17/22022 , A61B2017/22007 , A61B2017/22038 , A61B2017/22042 , A61B2018/00071 , A61B2018/00345 , A61M2025/0003
摘要: A guidewire includes an elongated member and a shaft extending distally from the elongated member, wherein the elongated member and shaft are configured to be navigated through vasculature of a patient. The guidewire further includes a first conductor extending around the shaft to define an outer perimeter of the guidewire and a first electrode adjacent the shaft. The first conductor is configured electrically connect the first electrode to an energy source. The guidewire further includes a second electrode and a second conductor configured to electrically couple the second electrode to the energy source. The first and second electrodes may be configured to deliver an electrical signal to fluid contacting the first and second electrodes to cause the fluid to undergo cavitation to generate a pressure pulse wave within the fluid.
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