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公开(公告)号：US10507545B2
公开(公告)日：2019-12-17
申请号：US15499127
申请日：2017-04-27
Applicant: MERIAL INC.
Inventor： Andy Brehm , Dennis Jerome Freeman , Ed Schindler , Julie Campbell
IPC: B41M5/26 , B23K26/362 , B41M5/24 , B23K26/12 , B23K28/00 , B23K37/047 , A01N1/02 , B23K26/361
Abstract: The invention relates to a machine for labeling “blank-labeled” cryogenically-frozen vials or ampoules, which contain heat-labile biological materials, and to which a laser-light sensitive material had been applied prior to freezing. Accordingly, the machine has been designed to maintain the integrity of the biological materials throughout all phases of the labeling process. The machine generally comprises a master control system; a programmable user interface; a frame; cryogenic freezer assemblies, for keeping the vials at the required low temperatures; an infeed assembly, configured to receive and position blank-labeled cryogenic vials; a cryostatic labeling/quality control tunnel, wherein the vials are maintained at the required temperature, labeled by laser ablation, and checked for quality; and, an outfeed assembly. The machine further comprises a means for transporting the vials from the infeed assembly to the tunnel, and from the tunnel to the outfeed assembly. Vials labeled according to the instant disclosure are ultimately manually or automatically loaded into cryogenic shipping containers.
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2.发明授权公开(公告)号：US10071582B2
公开(公告)日：2018-09-11
申请号：US15498933
申请日：2015-10-30
Applicant: MERIAL INC.
Inventor： Andy Brehm , Julie Campbell , Ed Schindler , Dennis Jerome Freeman
CPC classification number: B41M5/24 , A61J1/18 , A61J2200/44 , B41J3/4075 , B41M5/26 , B41M5/267
Abstract: This invention relates to an apparatus and method for applying writings and other markings to a frozen vial or ampoule, which is filled with biological material, and which is held at temperatures between about −70° C. and about −196° C. More particularly, the invention relates to a laser marking method that allows frozen vials to be labeled, while maintaining the integrity of the biological material contained therein.
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3.发明申请公开(公告)号：US20170246897A1
公开(公告)日：2017-08-31
申请号：US15498933
申请日：2015-10-30
Applicant: MERIAL INC.
Inventor： Andy Brehm , Julie Campbell , Ed Schindler
CPC classification number: B41M5/24 , A61J1/18 , A61J2200/44 , B41J3/4075 , B41M5/26 , B41M5/267
Abstract: This invention relates to an apparatus and method for applying writings and other markings to a frozen vial or ampoule, which is filled with biological material, and which is held at temperatures between about −70° C. and about −196° C. More particularly, the invention relates to a laser marking method that allows frozen vials to be labeled, while maintaining the integrity of the biological material contained therein.
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公开(公告)号：US20170312852A1
公开(公告)日：2017-11-02
申请号：US15499127
申请日：2017-04-27
Applicant: MERIAL INC.
Inventor： Andy Brehm , Dennis Jerome Freeman , Ed Schindler , Julie Campbell
IPC: B23K26/12 , B23K37/047 , B23K28/00 , B41M5/24 , B23K26/362
CPC classification number: B23K26/127 , A01N1/0236 , A01N1/0257 , A01N1/0268 , B23K26/361 , B23K26/362 , B23K28/00 , B23K37/047 , B41M5/24 , B41M5/26 , B41M5/262
Abstract: The invention relates to a machine for labeling “blank-labeled” cryogenically-frozen vials or ampoules, which contain heat-labile biological materials, and to which a laser-light sensitive material had been applied prior to freezing. Accordingly, the machine has been designed to maintain the integrity of the biological materials throughout all phases of the labeling process. The machine generally comprises a master control system; a programmable user interface; a frame; cryogenic freezer assemblies, for keeping the vials at the required low temperatures; an infeed assembly, configured to receive and position blank-labeled cryogenic vials; a cryostatic labeling/quality control tunnel, wherein the vials are maintained at the required temperature, labeled by laser ablation, and checked for quality; and, an outfeed assembly. The machine further comprises a means for transporting the vials from the infeed assembly to the tunnel, and from the tunnel to the outfeed assembly. Vials labeled according to the instant disclosure are ultimately manually or automatically loaded into cryogenic shipping containers.
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