公开(公告)号：US20230175047A1

公开(公告)日：2023-06-08

申请号：US17611099

申请日：2020-05-14

Applicant: BGI SHENZHEN ,  MGI TECH CO., LTD.

Inventor： Ao CHEN ,  Xun XU ,  Sha LIAO ,  Jin YANG ,  Longqi LIU ,  Ou WANG ,  Yuxiang LI ,  Guoxin TANG ,  Yuan JIANG ,  Chongjun XU ,  Ming NI ,  Wenwei ZHANG ,  Radoje DRMANAC ,  Snezana DRMANAC

IPC: C12Q1/6841 ,  C12Q1/6837 ,  C12N15/10

CPC classification number: C12Q1/6841 ,  C12Q1/6837 ,  C12N15/1093

Abstract: Provided are a method for detecting spatial information of nucleic acids in a sample, as well as a nucleic acid array used in the method and a method for producing the nucleic acid array.

公开(公告)号：US20210172009A1

公开(公告)日：2021-06-10

申请号：US16762898

申请日：2017-11-09

Applicant: MGI TECH CO., LTD.

Inventor： Yuan JIANG ,  Yang XI ,  Wenwei ZHANG ,  Pengjuan LIU ,  Xia ZHAO ,  Qiaoling LI ,  Hanjie SHEN ,  Yongwei ZHANG ,  Radoje DRMANAC

IPC: C12Q1/6834 ,  C12Q1/6855 ,  C12Q1/6876

Abstract: Provided are a hooked probe, a method for ligating a nucleic acid and a method for constructing a sequencing library. The hooked probe comprises a target specific area and a hooked area ligated thereto; the target specific area comprises a sequence complementarily paired with at least part of the single chain of the nucleic acid fragment to be ligated; the hooked area comprises a sequence unpaired with the nucleic acid fragment; the end of the hooked area is a ligatable end; and the ligatable end can ligate the end of the single chain of the nucleic acid fragment.