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公开(公告)号:US20090155294A1
公开(公告)日:2009-06-18
申请号:US12248587
申请日:2008-10-09
申请人: MICHAEL BUSCHLE , JURGEN FRISCH , CHRISTOPH KLADE , KAREN LINGNAU , WOLFGANG ZAUNER , GERD ZETTLMEISSL
发明人: MICHAEL BUSCHLE , JURGEN FRISCH , CHRISTOPH KLADE , KAREN LINGNAU , WOLFGANG ZAUNER , GERD ZETTLMEISSL
IPC分类号: A61K39/29
CPC分类号: C07K14/005 , A61K39/00 , A61K39/12 , A61K39/29 , A61K2039/55516 , A61K2039/55561 , C12N2770/24222 , C12N2770/24234
摘要: Disclosed are methods and compositions for inducing immune responses against Hepatitis C virus (HCV). The compositions comprise one or more epitope from a hotspot epitope. In certain embodiments, an HCV vaccine comprising at least two epitopes, each from a different hotspot epitope, is provided.
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公开(公告)号:US20090130135A1
公开(公告)日:2009-05-21
申请号:US12248744
申请日:2008-10-09
申请人: MICHAEL BUSCHLE , JURGEN FRISCH , CHRISTOPH KLADE , KAREN LINGNAU , WOLFGANG ZAUNER , GERD ZETTLMEISSL
发明人: MICHAEL BUSCHLE , JURGEN FRISCH , CHRISTOPH KLADE , KAREN LINGNAU , WOLFGANG ZAUNER , GERD ZETTLMEISSL
IPC分类号: A61K39/29
CPC分类号: A61K39/29 , A61K39/00 , A61K39/12 , A61K2039/55505 , A61K2039/55516 , A61K2039/55561 , A61K2039/57 , C07K14/005 , C12N2770/24222 , C12N2770/24234
摘要: Disclosed are methods and compositions for inducing immune responses against Hepatitis C virus (HCV). The compositions comprise one or more epitope from a hotspot epitope. In certain embodiments, an HCV vaccine comprising at least two epitopes, each from a different hotspot epitope, is provided.
摘要翻译: 公开了用于诱导针对丙型肝炎病毒(HCV)的免疫应答的方法和组合物。 组合物包含来自热点表位的一个或多个表位。 在某些实施方案中,提供了包含至少两个表位的HCV疫苗,每个表位各自为不同的热点表位。
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