公开(公告)号：US11145497B2

公开(公告)日：2021-10-12

申请号：US16308214

申请日：2017-06-06

Applicant: Micromass UK Limited

Inventor： Steven Pringle ,  Emrys Jones ,  Mike Morris ,  Keith Richardson ,  Zoltan Takats

IPC: H01J49/00 ,  A61B5/00 ,  G01N21/71 ,  G01N27/622 ,  H01J49/16 ,  A61B1/313 ,  A61B18/00

Abstract: A method of analysing a target is disclosed comprising ablating a portion of a target so as to cause an aerosol plume to be produced and light or other electromagnetic radiation to be emitted. The aerosol plume is analysed using mass spectrometry and/or ion mobility spectrometry and the emitted light or other electromagnetic radiation is analysed using optical spectroscopy in order to determine one or more regions of interest of the target and/or one or more margins or bounds of a region of interest of the target.

公开(公告)号：US11133169B2

公开(公告)日：2021-09-28

申请号：US16306821

申请日：2017-06-05

Applicant: MICROMASS UK LIMITED

Inventor： Emrys Jones ,  Richard Chapman ,  Steven Pringle

IPC: H01J49/00 ,  H01J49/14 ,  H01J49/16

Abstract: Apparatus is disclosed comprising a first ion source (210) arranged and adapted to emit a spray of charged droplets (211) and a detector or sensor (203) arranged and adapted automatically to detect, sense or determine one or more first parameters or properties of the spray of charged droplets (211) as the spray of charged droplets (211) impacts upon a surface of the detector or sensor 203. The apparatus further comprises a control system (204) arranged and adapted to adjust, correct and/or optimise one or more second parameters or properties of the spray of charged droplets (211) based on the one or more first parameters or properties of the spray of charged droplets (211) detected, sensed or determined by the detector or sensor (203).

公开(公告)号：US20190267221A1

公开(公告)日：2019-08-29

申请号：US16308214

申请日：2017-06-06

Applicant: Micromass UK Limited

Inventor： Steven Pringle ,  Emrys Jones ,  Mike Morris ,  Keith Richardson ,  Zoltan Takats

IPC: H01J49/00 ,  H01J49/16 ,  G01N21/71 ,  G01N27/62 ,  A61B5/00

Abstract: A method of analysing a target is disclosed comprising ablating a portion of a target so as to cause an aerosol plume to be produced and light or other electromagnetic radiation to be emitted. The aerosol plume is analysed using mass spectrometry and/or ion mobility spectrometry and the emitted light or other electromagnetic radiation is analysed using optical spectroscopy in order to determine one or more regions of interest of the target and/or one or more margins or bounds of a region of interest of the target.